TRADITIONAL POSTER - ismrm

Poster Sessions
breasts. Here, we show our experience in 2D breast ASL using FAIR labeling and background suppression in both volunteers and patients. With our
technique, higher perfusion signal was depicted in tumor.
2502. Improved Fat Suppression with High Resolution Balanced Steady State Imaging in the Breast
Dorothee Barbara Engel 1 , Catherine Judith Moran 2 , Fred Kelcz 3 , Stephan O. Schoenberg 1 , Walter Block 2
1 Clinical Radiology and Nuclear Medicine, University Medical Center Mannheim, Mannheim, Germany; 2 Department of Medical
Physics, University of Wisconsin, Madison, WI, United States; 3 Department of Radiology, University of Wisconsin, Madison, WI,
United States
While the Dynamic Contrast Enhanced (DCE) acquisition remains the centerpiece of breast MRI, both signal intensity and the depiction of lesion
morphology in T2-weighted images can help to distinguish malignant versus benign lesions. With TRs on the order of seconds, T2-weighted acquisitions are
generally inefficient and most often acquired with high in-plane resolution but low through plane resolution. A radial bSSFP acquisition termed 3DPR-SSFP
has been shown to provide improved depiction of lesion morphology in comparison to conventional T2-weighed acquisitions. We evaluate the performance
of two methods for improving fat suppression of 3DPR-SSFP while retaining the advantage of clear depiction of fine morphological details in the breast.
2503. Resolving Arterial Phase in Dynamic Breast MRI Using a Fast TWIST Acquisition During Injection
Delay
Karl-Heinz Herrmann 1 , Pascal A. Baltzer, Ines Krumbein, Christian Geppert 2 , Werner A. Kaiser, Jürgen R.
Reichenbach 1
1 Medical Physics Group, Department of Diagnostic and Interventional Radiology, University Hospital Jena, Jena, Thüringen,
Germany; 2 MR Oncology, Siemens Healthcare, Erlangen
In MR Mammography pathologic vascularisation is utilized for the diagnosis of tumors. Many standard dynamic MRM protocols contain a delay of 35s,
during which the contrast agent is applied, between the native scan and the following multiple post-CA scans. This injection delay can be efficiently used to
acquire additional dynamic data sets with both high temporal (5.7s) and spatial resolution (0.9x0.9x1.5mm) using a 3D gradient echo view sharing sequence
with stochastic trajectories (TWIST). This allows to resolve the arterial phase of the contrast agents first pass and helps to detect anomalous arterial supply
vessels to suspect lesions.
Lung & Mediastinum MRI
Hall B Wednesday 13:30-15:30
2504. Inflammation Assessment in the Lungs of LPS-Challenged Rodents: Comparison Between Radial
Ultra-Short Echo Time (UTE) and Cartesian MR Imaging
Magdalena Zurek 1 , Laura Carrero-Gonzalez 2,3 , Selina Bucher 2 , Thomas Kaulisch 2 , Detlef Stiller 2 , Yannick
Crémillieux 1
1 Université de Lyon, Laboratoire CREATIS-LRMN, Lyon, France; 2 Boehringer Ingelheim Pharma GmbH & Co. KG, Biberach,
Germany; 3 Universidad Complutense de Madrid, Madrid, Spain
A radial ultra short-echo time (UTE) sequence has been shown to be appropriate in pulmonary imaging due to its robustness against motion and its improved
image resolution. In this study, we evaluated the accuracy of edema detection using two protocols based on conventional-Cartesian and UTE radial imaging
approaches. Despite degraded image quality in case of Cartesian images due to the motion, similar inflammation extent was found for both approaches. The
UTE technique, applied under free-breathing conditions, will certainly prove to be quite useful in routine MR investigations applied on models of lung
diseases associated with inflammation or mucous hypersecretion.
2505. Ultrashort Echo Time (UTE) MR Lung Imaging with Respiratory Motion Compensation
Jiangsheng Yu 1 , Yiqun Xue 1 , Hamidreza Saligheh Rad 1 , Hee Kwon Song 1
1 Laboratory for Structural NMR Imaging, Department of Radiology,, University of Pennsylvania, Philadelphia, PA, United States
Ultra-short echo time (UTE) MRI has been successfully applied to lung imaging, but so far the issue of respiratory motion during imaging the lung
parenchyma has not yet been addressed. In this work, a respiratory motion-compensated UTE lung MRI technique is presented. This technique applies the
golden-angle view increment strategy in conjunction with respiratory self-gating to reconstruct images at different respiratory phases to reduce respiratory
motion artifacts. The in-vivo results demonstrate that lung image quality is significantly enhanced with improved visualization and delineation of lung
vasculature, as well as improved SNR, as compared to conventional gradient echo images.
2506. Comparison of Lung T2* Measurements at 1.5T and 3.0T with Ultrashort Echo Time (UTE) Sequence
Jiangsheng Yu 1 , Yiqun Xue 1 , Hee Kwon Song 1
1 University of Pennsylvania, Philadelphia, PA, United States
Accurate assessments of lung T2* may be important as it has the potential to detect structural and functional changes caused by lung diseases such as
emphysema, chronic bronchitis and fibrosis. While measurements have been carried out in both animals and humans at 1.5T, studies on human lung at 3T
have not yet been reported. In this work, we compare T2* values in normal human lungs at 1.5T and 3.0T using an ultrashort echo time (UTE) pulse
sequence. Results show the average lung T2* of 0.72 (±0.17) ms at 3.0T is considerably shorter than 2.2 (±0.43) ms at 1.5T.