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TRADITIONAL POSTER - ismrm

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Poster Sessions<br />

2004. Magnetization Transfer and Spin-Lattice Relaxation Time Measurements of White Matter Lesions in<br />

Normal Aging<br />

Mark E. Bastin 1 , Maria Valdés Hernandez 2 , Susana Muñoz Maniega 2 , Catherine Murray 3 , Alan J. Gow 3 ,<br />

Paul A. Armitage 2 , Joanna M. Wardlaw 2 , Ian J. Deary 3<br />

1 Medical Physics, University of Edinburgh, Edinburgh, United Kingdom; 2 Clinical Neurosciences, University of Edinburgh,<br />

Edinburgh, United Kingdom; 3 Psychology, University of Edinburgh, Edinburgh, United Kingdom<br />

White matter lesions are a common finding on T2- and FLAIR-weighted MRI scans of older subjects, but their etiology and relationship to cognitive<br />

function remains unclear. The aim of this pilot study was to characterize differences in magnetization transfer ratio and spin-lattice relaxation time between<br />

macroscopically normal-appearing white matter and white matter lesions in a subset of a unique cohort of aging subjects, the Lothian Birth Cohort 1936.<br />

2005. Hypertension, Arterial Health and Neuronal Integrity in Midlife<br />

Andreana P. Haley 1,2 , Tarumi Takashi 3 , Jun Sugawara 3 , Hirofumi Tanaka 3<br />

1 Psychology, The University of Texas at Austin, Austin, TX, United States; 2 UT Imaging Research Center, Austin, TX, United States;<br />

3 Kinesiology, The University of Texas at Austin, Austin, TX, United States<br />

The present study bridges the gap between midlife hypertension and late-life cognitive impairment, a relationship that has long been documented but remains<br />

poorly understood. We demonstrate that midlife hypertension and associated arterial thickening relate to cerebral measures of neuronal health and viability<br />

in middle-aged adults with intact cognitive performance.<br />

2006. Comparison of Brain Metabolites Changes Associated with Visual Sexual Arousal in Premenopausal<br />

and Menopausal Women: Functional MR Spectroscopy<br />

Tae-Hoon Kim 1 , Gwang-Woo Jeong 1,2 , Han-Su Baek 1 , Gwang-Won Kim 1 , Heoung-Keun Kang 2 , Jong-Chul<br />

Yang 3 , Kwangsung Park 4<br />

1 Interdisplinary Program of Biomedical Engineering, Chonnam National University Medical School, Gwangju, Korea, Republic of;<br />

2 Radiology, Chonnam National University Medical School, Gwangju, Korea, Republic of; 3 Psychiatry, Chonbuk National University<br />

Hospital, Chonbuk, Korea, Republic of; 4 Urology, Chonnam National University Medical School, Gwangju, Korea, Republic of<br />

With menopause, women underwent changes of overall hormones, leading to functional changes of organs. A majority of menopausal women experience<br />

some exchanges in sexual function. Using fMRI technique, menopausal a few papers concerning differential brain activation patterns between<br />

premenopausal and menopausal women were published. However, it is unclear how brain metabolite change in menopause affects sexual arousal.<br />

The purpose of this study was to investigate the brain metabolic changes associated with visual sexual arousal in premenopausal and menopausal women<br />

using functional MR spectroscopy (fMRS).<br />

2007. Motion Detection in Healthy Young, Middle-Aged, and Elderly Adults Using a Water Signal Based<br />

Navigator Echo: A 1 H MRS Study<br />

Sarah Andrea Wijtenburg 1 , Kathleen L. Fuchs 2 , Virginia I. Simnad 3 , Jack Knight-Scott 1<br />

1 Radiology, Children's Healthcare of Atlanta, Atlanta, GA, United States; 2 Neurology, University of Virginia, Charlottesville, VA,<br />

United States; 3 Neurology, Evergreen Hospital Medical Center, Kirkland, WA, United States<br />

Here, we build upon our earlier work incorporating a CHESS pulse into a STEAM sequence by presenting a new method for analyzing and interpreting<br />

motion data collected from three age groups: healthy young (HY), healthy middle-aged (HM), and healthy elderly (HE). Our results show that listed in<br />

increasing order of motion during a 1 H MRS STEAM spectroscopy examination: HY, HM, and HE.<br />

2008. Cross-Site Reproducibility of 1 H-MRS<br />

Irene Margaret Vavasour 1 , Cornelia Laule 1 , Burkhard Maedler 2 , Trudy Harris 1 , David K.B. Li 1 , Anthony<br />

L. Traboulsee 3 , Alex L. MacKay 1<br />

1 Radiology, University of British Columbia, Vancouver, BC, Canada; 2 Physics and Astronomy, University of British Columbia;<br />

3 Medicine, Univeristy of British Columbia<br />

Quantitative assessment of 1 H-MRS metabolite concentrations has the potential to be an in-vivo marker for disease progression and treatment efficacy in<br />

pharmaceutical trials. The present study examines cross-site reproducibility of 1 H-MRS metabolite concentrations measured on the same 5 people at 6 sites.<br />

Average percent differences of inter and intra-site reproducibility was

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