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Poster Sessions<br />

1424. Non-Contrast-Enhanced Renal Venography Using Spatial Labeling with Multiple Inversion Pulses (<br />

SLEEK )<br />

Hao Shen 1 , Guang Cao 2<br />

1 Applied Science Laboratory, GE Healthcare, Beijing, China; 2 Applied Science Laboratory, GE Healthcare, Hong Kong, China<br />

Renal venogram is important in clinical diagnosis but difficult to image with the existing MRI technique. In this study, we developed a non-contrastenhanced<br />

renal venography using a spatial labeling with multiple inversion pulses prepared balanced steady-state free precession sequence.<br />

1425. Fast Vessel Scout Imaging Based on Continuously Moving Table Acquisitions of Projection Data<br />

Sandra Huff 1 , Michael Markl 1 , Ute Ludwig 1<br />

1 Department of Diagnostic Radiology, Medical Physics, University Hospital Freiburg, Freiburg, Germany<br />

MRA of the peripheral arteries is typically based on a contrast enhanced multistation bolus-chase approach, which requires good synchronization of data<br />

acquisition, table motion and arterial passage of the contrast agent bolus. These challenges imply the need for careful planning for the consecutive<br />

acquisitions of the several stations and prior knowledge of the vessel geometry would thus be desirable. This study presents the implementation of a fast<br />

peripheral vessel scout based on Continuously Moving Table acquisition of projection data with Time-of-Flight (TOF) contrast. The variation of arterial<br />

TOF signal during the cardiac cycle was exploited to enhance blood-background contrast.<br />

1426. Optimization and Comparison of Non-Contrast-Enhanced Inflow-Sensitive Inversion Recovery BSSFP<br />

for Renal and Mesenteric MRA at 1.5T and 3.0T<br />

Caroline Denison Jordan 1,2 , Pauline Wong Worters 1 , Shreyas S. Vasanawala 1 , Bruce L. Daniel 1 , Marc T.<br />

Alley 1 , Moritz F. Kircher 1 , Robert J. Herfkens 1 , Brian A. Hargreaves 1<br />

1 Radiology, Stanford University, Stanford, CA, United States; 2 Bioengineering, Stanford University, Stanford, CA, United States<br />

Contrast-enhanced MR angiography is a widely accepted technique for imaging the kidneys, but there are many reasons to explore non-contrast-enhanced<br />

MRA methods, including contraindication of gadolinium for patients with kidney disease. We evaluated one non-contrast enhanced MRI technique which<br />

has shown promising results: respiratory-triggered bSSFP with In Flow Inversion Recovery (IFIR). We optimized the inversion times at 1.5T and 3T, and<br />

then quantitatively and qualitatively compared images of renal and mesenteric arteries. We found better relative contrast and better visualization of renal and<br />

mesenteric arteries at 3T. An inversion time of 800 ms gave the optimal relative contrast.<br />

1427. Feasibility of Refocused Turbo Spin Echo (RTSE) for Clinical Noncontrast MRA<br />

Samuel W. Fielden 1 , John P. Mugler III 1,2 , Patrick T. Norton 2,3 , Klaus D. Hagspiel 2,3 , Christopher M.<br />

Kramer 2,3 , Craig H. Meyer 1,2<br />

1 Biomedical Engineering, University of Virginia, Charlottesville, VA, United States; 2 Radiology, University of Virginia,<br />

Charlottesville, VA, United States; 3 Medicine, University of Virginia, Charlottesville, VA, United States<br />

rTSE hybridizes the increased signal provided by the 180° refocusing RF pulses of RARE and the better flow performance of the fully-refocused gradients<br />

and phase alternation of balanced SSFP. Here we demonstrate the feasibility of the rTSE sequence in a clinical setting by acquiring angiograms via the<br />

rTSE sequence in patients scheduled for peripheral runoff examinations and, in one patient, by comparing the rTSE angiogram to a TOF angiogram.<br />

1428. Whole Body TOF Mouse Magnetic Resonance Angiography<br />

William Lefrançois 1 , Wadie Ben Hassen, Stéphane Sanchez, Jean-Michel Franconi, Eric Thiaudière,<br />

Sylvain Miraux<br />

1 Résonance Magnétique des Systèmes Biologiques, UMR 5536 CNRS-Univ. Bordeaux 2, Bordeaux, Gironde, France, Metropolitan<br />

Vascular diseases, particularly atherosclerosis, are a major health problem in developed countries. In some cases, stenosis can become critical and cause<br />

coronary heart disease necessitating surgical interventions. Therapy planning in patients with multiple stenosis could be facilitated by using whole body<br />

angiography. MR angiography (MRA) method currently used on human, is first-pass MRA using a Gadolinium contrast agent. However, this method can<br />

not be used on small animal models. This study aimed to develop a fast Time-of-Flight-MRA method able to screen the whole body in reasonable<br />

acquisition times and assess the degree and extent of stenosis.<br />

1429. The Origins of Bright Blood MPRAGE at 7 Tesla and a Simultaneous Method for T1 Imaging and<br />

Non-Contrast MRA<br />

John W. Grinstead 1 , William Rooney 2 , Gerhard Laub<br />

1 Siemens Healthcare, Portland, OR, United States; 2 Oregon Health and Science University<br />

MPRAGE is a widely used pulse sequence for T1-weighted anatomical imaging. It has been reported that blood appears extremely bright in MPRAGE at 7<br />

Tesla, and provides excellent vascular information. However, the mechanism for this has not been completely explained. The present work explains the<br />

primary source of bright blood MPRAGE at 7 Tesla, and based on this understanding proposes a new technique providing simultaneous high-resolution T1<br />

MPRAGE imaging and non-contrast angiography with excellent background suppression.<br />

1430. Volumetric Phase Contrast Flow Imaging with Multiple Station Isocenter Acquistion Substantially<br />

Improves Flow Results<br />

Andreas Greiser 1 , Mehmet Akif Gulsun 2 , Arne Littmann 1 , Jens Guehring 2 , Edgar Mueller 1<br />

1 Siemens AG Healthcare Sector, Erlangen, Germany; 2 Siemens Corporate Research, Princeton, NJ, United States<br />

Vector-encoded MR phase contrast acquisitions covering a bigger volume show larger errors in velocity due to eddy currents and gradient non-linearities. A<br />

new scan method is presented that acquires the volumetric dataset in multiple z-isocentered steps. The resulting corrected velocity images and the influence<br />

on the flow quantification results of the descending aorta and flow field visualization were analyzed. The multiply isocentered approach results in an overall<br />

increase of peak velocity estimates and flow values. The pixelwise standard deviation of the calculated background phase correction matrices across slices<br />

for fixed table position was 1.76 cm/sec vs. 0.61 cm/sec for z-isocentered.

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