TRADITIONAL POSTER - ismrm

Poster Sessions
strong similarities the CFD simulation and in-vitro measurement. The simulation of PC-MRI of fluctuating flow may facilitate controlled studies of the
effects of velocity fluctuations on the PC-MRI signal and the optimization of IVSD mapping.
1343. Reducing the Scan Time of Time-Resolved, 3D Phase Contrast Imaging with 2D Autocalibrated
Parallel Imaging
Marcus T. Alley 1 , Philip J. Beatty 2 , Albert Hsiao 1 , Shreyas S. Vasanawala 1
1 Radiology, Stanford University, Stanford, CA, United States; 2 MR Applied Science Lab, GE Healthcare, Menlo Park, CA, United
States
Time-resolved 3-dimensional phase-contrast MR imaging (3D-PC MRI) has developed as an active area of research for vascular imaging. In general
however the clinical adoption of this approach for routine vascular imaging has been hampered by the long acquisition times inherent in the technique (on
the order of 10-20 minutes). Several groups have addressed this issue by using parallel imaging to accelerate data acquisition in one dimension, and in this
work we demonstrate the ability to perform auto-calibrated parallel imaging in both the in-plane and slice directions to reduce the overall scan time to the
order of several minutes.
1344. Reproducibility of Pulse Wave Velocity Measurements with Phase Contrast Magnetic Resonance and
Applanation Tonometry
Jonathan D. Suever 1 , David Huneycutt 2 , Enrique Rojas-Campos 3 , Francesca Cardarelli 3 , Sam Fielden 2 ,
Arthur Stillman, 2,3 , Paolo Raggi 3 , John N. Oshinski, 12
1 Biomedical Engineering, Georgia Institute of Technology / Emory University, Atlanta, GA, United States; 2 Radiology, Emory
University School of Medicine, Atlanta, GA, United States; 3 Cardiology, Emory University School of Medicine, Atlanta, GA, United
States
Increased aortic pulse wave velocity (PWV) due to arterial stiffening is commonly seen in patients with hypertension. Clinically, applanation tonomtery is
used to measure PWV; however, we have developed a new method that uses PCMR combined with cross-correlation analysis. The purpose of this study was
to compare the reproducibility of cross-correlation and applanation tonometry in normals and patients. In normal volunteers, the reproducibility of crosscorrelation
technique was better than applanation tonometry. In patients, cross-correlation and applanation tonometry measurements were not statistically
different.
1345. Quantification of Pre-Systolic Left Ventricular 4D Blood Flow Organization in Normal and Failing
Hearts
Jonatan Eriksson 1 , Petter Dyverfeldt 1 , Jan Engvall 1 , Ann F. Bolger 2 , Tino Ebbers 1 , Carl-Johan Carlhäll 1
1 Linköping University and Center for Medical Image Science and Visualization (CMIV), Linköping, Sweden; 2 University of
California San Francisco, San Francisco, CA, United States
Multidimensional patterns of intracardiac blood flow remain poorly characterized in health and disease. An extended pathline based left ventricular (LV) 4D
blood flow quantification approach is presented. Three-directional, three-dimensional cine phase-contrast MRI data was acquired in healthy subjects and
patients with idiopathic dilated cardiomyopathy and analyzed for assessment of the pre-systolic LV blood flow organization, in order to evaluate the
preparation of different flow components for systolic outflow. Quantification of pre-systolic orientation may reflect an aspect of ventricular systolic
efficiency that is impacted by flow-specific organization inside the diastolic ventricle.
1346. Aortic Pulse Pressure Evaluation Using Fourier Velocity Encoded MR M-Mode
Valentina Taviani 1 , Stacey S. Hickson 2 , Christopher J. Hardy 3 , Andrew James Patterson 1 , Victoria E.
Young 1 , Mark Butlin 4 , Carmel M. McEniery 2 , Ian B. Wilkinson 2 , Jonathan Harvey Gillard 1 , Martin J.
Graves 1
1 Department of Radiology, University of Cambridge, Addenbrooke's Hospital, Cambridge, United Kingdom; 2 Clinical Pharmacology
Unit, University of Cambridge, Addenbrooke's Hospital, Cambridge, United Kingdom; 3 GE Global Research, Niskayuna, NY, United
States; 4 The Australian School of Advanced Medicine, Macquarie University, Sydney, Australia
Central pulse pressure (PP) is a major determinant of ventricular afterload which can be accurately measured only by means of invasive pressure
measurements. In this work, we present a method based on Fourier velocity encoded M-mode and the cross-section-averaged flow equations to estimate the
local PP in the aorta. The obtained results were found to be in good agreement with applanation tonometry performed in a cohort of 18 healthy volunteers
(bias=1.25mmHg, 95% limits of agreement (LOA) = [-5.7,8.2]mmHg) and intravascular pressure measurements obtained in 4 patients undergoing diagnostic
catheterization ((bias=-0.37mmHg, 95% LOA = [-9.2,8.4]).
1347. Association of Wall Compliance with Intraluminal Thrombus, Calcification, and the Size of Infrarenal
Abdominal Aortic Aneurysm: An in Vivo MR Phase-Contrast Angiography Study
Hong Ye 1 , Gador Canton 2 , Xihai Zhao 2 , William Kerwin 2 , Chun Yuan 2 , Zhanming Fan 1
1 Department, Beijing Anzhen hospital, Capital Medical University, Beijing, China; 2 Radiology, University of Washington, Seattle,
WA, United States
AAA rupture related risk factors include maximum diameter, wall stress or compliance, intraluminal thrombus (ILT), and calcification. The assessment of
the correlations among these factors may improve the management and prognosis of AAA. This study investigated the association of wall compliance with
ILT, calcification, and the size of infrarenal AAA using in vivo PC-MRA in 48 patients. We found the wall compliance was positively associated with ILT,
which suggests thrombus may be a protective factor for AAA rupture. In addition, our results indicate that length to maximum diameter ratio may be a
stronger indicator for wall compliance.