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Poster Sessions<br />

2609. Clinical Application for Cirrhosis with Susceptibility Weighted Imaging<br />

Yongming Dai 1 , Daoying Gen 2 , Wei Cheng 3 , E.M. Haacke 4<br />

1 Siemens Ltd China, Healthcare, Magnetic Resonance Imaging, Shanghai, China; 2 Fudan University affiliated Huashan Hospital; 3 The<br />

Third Military Medical University affiliated SouthWest hospital; 4 Wayne State University, United States<br />

In this study we extended clinical application for hepatic disease (Cirrhosis)with susceptibility weighted imaging (SWI). The results showed promising<br />

future for SWI application in human abdomen.<br />

2610. A Software Phantom Generator System for Quality Control (QA) of MRI Iron Overload Assessment<br />

Software<br />

Bahman Kasmai 1 , Paul Napier Malcolm 1 , Andoni Paul Toms 1 , Andrew Brian Gill 2<br />

1 Radiology, Norfolk & Norwich University Hospitals NHS Trust, Norwich, Norfolk, United Kingdom; 2 Radiology, Papworth Hospital<br />

NHS Foundation Trust, Cambridge, Cambridgeshire<br />

The aim of this work was to develop a software tool for validation, evaluation and integrity checks of in-house and commercial MRI iron overload systems.<br />

A windows-based software application, called SOFGEN, written in C# and based on Microsoft .NET framework generates a sets of fully Dicom compliant<br />

images from a set of user supplied parameters and decay model, for testing of Dicom compliant MRI T2(*) assessment software. The SOFGEN generated<br />

phantoms were successfully used to evaluate a number of in-house developed T2(*) assessment software and is available free via email request to authors.<br />

2611. Effects of Posprandial State and Mesenteric Blood Flow on the Repeatability of Magnetic Resonance<br />

Elastography<br />

Catherine D. G. Hines 1 , Mary J. Lindstrom 2 , Scott B. Reeder 1,3<br />

1 Biomedical Engineering, University of Wisconsin-Madison, Madison, WI, United States; 2 Biostatistics and Medical Informatics,<br />

University of Wisconsin-Madison, Madison, WI, United States; 3 Radiology, University of Wisconsin-Madison, Madison, WI, United<br />

States<br />

Blood flow and fasting status are recognized sources of variability in MRE measurements, and their impact on the repeatability of MRE is evaluated. MRE<br />

stiffness values and flow through the superior mesenteric vein were measured in twelve healthy volunteers in fasted and fed states, and the sequences were<br />

repeated five weeks later. No significant differences between fasted/fed state stiffness values and no correlation between values and measured flow are seen.<br />

Overall, volunteers scanned in a known fasted or fed state provide very repeatable MRE stiffness values, where the standard deviation of one MRE exam is<br />

8.5% or 9.0% for fasted and fed states, respectively.<br />

2612. Three-Dimensional MRCP with Reduced RF Power Deposition<br />

John P. Mugler, III 1 , Wilhelm Horger 2 , Berthold Kiefer 2<br />

1 Radiology, University of Virginia, Charlottesville, VA, United States; 2 Siemens Healthcare, Erlangen, Germany<br />

This work explored two approaches for reducing the RF power deposition of MRCP imaging based on a turbo-spin-echo pulse sequence. An adiabatic T2<br />

preparation applied just before the excitation RF pulse, or a very long first echo spacing, combined with partial-Fourier acquisition permitted power<br />

deposition to be reduced by 25%-40% compared to that for a standard MRCP pulse sequence, while providing image quality comparable to that for the<br />

standard method. These methods will be valuable for addressing power-deposition limitations of MRCP at 3T, and will permit more consistent MRCP<br />

image quality to be achieved.<br />

2613. T2-Weighted Body Imaging with PROPELLER Using Parallel Imaging with Across Blade Calibration<br />

James H. Holmes 1 , Philip J. Beatty 2 , Scott B. Reeder 3,4 , Zhiqiang Li 5 , Reed F. Busse 1 , Ajeetkumar<br />

Gaddipati 6 , Jean H. Brittain 1<br />

1 Applied Science Laboratory, GE Healthcare, Madison, WI, United States; 2 Applied Science Laboratory, GE Healthcare, Menlo Park,<br />

CA; 3 Radiology, University of Wisconsin-Madison, Madison, WI, United States; 4 Medical Physics, University of Wisconsin-Madison,<br />

Madison, WI, United States; 5 GE Healthcare, Phoenix, AZ; 6 GE Healthcare, Waukesha, WI, United States<br />

This work demonstrates the application of a shared calibration scheme for autocalibrated parallel imaging to enable greater blade acceleration for abdominal<br />

PROPELLER. The shared calibration method uses external calibration data as well as a small amount of internal calibration data per blade. The technique is<br />

shown to improve robustness to motion for free-breathing T2-weighted abdominal body imaging. Results were found to compare favorably to respiratorygated<br />

Cartesian exams suggesting that the PROPELLER approach may allow robust imaging in individuals where respiratory gating is not effective.<br />

2614. Balanced MR Cholangiopancreatography with Motion-Sensitized Driven-Equilibrium (MSDE):<br />

Feasibility and Optimization of Imaging Parameter<br />

Tomohiro Nakayama 1 , Takashi Yoshiura 1 , Yukihisa Takayama 1 , Eiki Nagao 1 , Tsuyoshi Tajima 1 , Akihiro<br />

Nishie 1 , Yoshiki Asayama 1 , Kousei Ishigami 1 , Daisuke Kakihara 1 , Daisuke Okamoto 1 , Hiroshi Honda 1 ,<br />

Tomoyuki Okuaki 2<br />

1 Clinical Radiology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan; 2 Philips Electronics Japan<br />

Motion-sensitized driven-equilibrium (MSDE) preparation was added to a balanced SSFP MRCP sequence in order to suppress disturbing high signal<br />

intensities from flowing blood in vessels. We performed a volunteer study to determine optimal VENC value for the evaluation of biliary systems. We found<br />

the optimum VENC values to be 3 or 5cm/s with best suppression of relative vessel signals to bile ducts. At a lower VENC value (1cm/s), signal of bile duct<br />

was reduced likely due to minimal biliary flow. Higher VENC values (> 7cm/s) resulted in failure of vessel signal suppression.

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