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Poster Sessions<br />

refocusing flip angles. Volunteer experiments were acquired in 3D low refocusing flip angle TSE (LOWRAT) using a 3.0T imager. The optimal parameter<br />

for T1-optimized black-blood imaging was low excitation flip angles, low refocusing flip angles, NPHA pseudo steady-state preparation, short ETL, best<br />

echo number for K-space center=2nd echo, and shortest TR. Contrast behavior of 3D LOWRAT T1W was similar to that of 2D SE. This optimal sequences<br />

can be used for 3D volumetric T1 weighted black-blood imaging.<br />

3032. Rapid Optimization of Acquisition Parameters for Fast Spin Echo Imaging in RF Power Constrained<br />

Regimes<br />

Robert Marc Lebel 1 , Alan W. Wilman 1<br />

1 Biomedical Engineering, University of Alberta, Edmonton, Alberta, Canada<br />

At high field strengths, fast spin echo is a SAR constrained procedure; parameter concessions are required to enable its use. Typical modifications include<br />

elongated RF pulses and reduced refocusing angles. We present an SNR analysis investigating the effects of reduced angles (lower signal) and longer RF<br />

pulses (less readout time) and present a reliable method for rapidly selecting these parameters to optimize the SNR for a given target power level.<br />

3033. Reduced SAR with BASE Sequence at 7 Tesla<br />

Daniel Neumann 1 , Morwan Choli 2 , Martin Blaimer 2 , Michael Bock 3 , Felix Breuer 2 , Peter M. Jakob 4<br />

1 Experimental Physics 5, University of Würzburg, Würzburg, Germany; 2 Experimental Physics 5, Research Center Magnetic<br />

Resonance Bavaria (MRB), Würzburg, Germany; 3 Department of Medical Physics in Radiology, German Cancer Research Center<br />

(dkfz), Heidelberg, Germany; 4 Experimental Physics 5, University of Würzburg, Würzburg, Bavaria, Germany<br />

The step towards higher magnetic fields on the one hand provides a stronger NMR signal while on the other hand SAR is significantly increased in<br />

comparison with standard clinical scanners. Therefore the application of sequences using many refocusing pulses such as TSE can be difficult.<br />

In this work we examine the potential of the BASE sequence to obtain high resolution images at 7T. BASE is a combination of BURST and multiple<br />

refocusing pulses. However, compared to TSE, there are a lower number of pulses and therefore SAR could be reduced by a factor of four.<br />

3034. Whole-Brain FLAIR Using 3D TSE with Variable Flip Angle Readouts Optimized for 7 Tesla<br />

John W. Grinstead 1 , Oliver Speck 2 , Dominik Paul, Lisa Silbert 3 , Louis Perkins 3 , William Rooney 3<br />

1 Siemens Healthcare, Portland, OR, United States; 2 Biomedical Magnetic Resonance, Otto-von-Guericke-University, Magdeburg,<br />

Germany; 3 Oregon Health and Science University<br />

Routine FLAIR uses a 2D inversion-recovery turbo spin echo pulse sequence having many high-SAR RF pulses, allowing only a few slices to be acquired at<br />

7 Tesla. Recent work demonstrated the feasibility of using 3D IR-TSE with a T2-prepared IR and a reduced flip angle readout of 70 degrees to perform<br />

whole brain FLAIR at 7 Tesla for the first time. The present work extends this approach with a variable flip angle readout optimized for the T1 and T2<br />

values of brain tissues at 7 Tesla to further improve the SAR, contrast, and SNR performance.<br />

3035. Inversion of a Non-CPMG Fast Spin Echo Train.<br />

Patrick H. Le Roux 1<br />

1 Applied Science Lab, GE Healthcare, Palaiseau, IDF, France<br />

The non-CPMG sequence permits to acquire MR signal in the Fast Spin Echo mode even when the CPMG (Carr Purcell Meiboom Gill) phase conditions<br />

cannot be fulfilled. It consists in a quadratic phase modulation of the refocusing pulses train, preceded by a suitable preparation period. It turns out that this<br />

sequence of RF pulses can be readily inversed permitting a perfect Driven Equilibrium scheme to be applied.<br />

3036. Verse-Space<br />

Guobin Li 1 , Christoph Sauerbier 2 , Dominik Paul 3 , Weijun Zhang 1 , Qiang He 1 , Marc Beckmann 1 , Lars<br />

Lauer 3<br />

1 Siemens Mindit Magnetic Resonance Ltd., Shenzhen, Guang Dong, China; 2 Hochschule Furtwangen University, Germany; 3 Siemens<br />

Medical Solutions, Erlangen, Germany<br />

Slab selection by the dual echo-spacing technique in SPACE with non-selective refocusing pulses needs averaging with phase cycling ans is sensitive to<br />

chemical shift artifacts during excitation. A new technique, VERSE-SPACE is presented in this abstract to provide faster acquisition speed and better slab<br />

profile than the previous technique.<br />

3037. Multi-Slab SPACE<br />

Guobin Li 1 , Dominik Paul 2 , Weijun Zhang 1 , Tallal Charles Mamisch 3 , Qiang He 1 , Marc Beckmann 1 , Lars<br />

Lauer 2<br />

1 Siemens Mindit Magnetic Resonance Ltd., Shenzhen, Guang Dong, China; 2 Siemens Medical Solutions, Erlangen, Germany;<br />

3 Department of Orthopaedic Surgery, Inselspital, University of Berne, Bern, Switzerland<br />

In Single Slab SPACE, relative short TR and long echo train have to be used to reduce the total acquisition time into clinical acceptable range at the cost of<br />

the degradation in contrast purity and SNR, especially in PDw imaging. A new Multi-Slab SPACE is presented here to further increase the sampling<br />

efficiency, and then provides more flexibility to use longer TR and shorter echo train acquisition compared to Single Slab SPACE.<br />

3038. Fast Spin-Echo Imaging of Inner Field-Of-Views Using 2D-Selective RF Excitations<br />

Jürgen Finsterbusch 1,2<br />

1 Department of Systems Neuroscience , University Medical Center Hamburg-Eppendorf, Hamburg, Germany; 2 Neuroimage Nord,<br />

University Medical Centers Hamburg-Kiel-Lübeck, Hamburg-Kiel-Lübeck, Germany<br />

Fast spin-echo imaging suffers from image blurring if a large number of echoes per excitation (turbo factor) is used and, in particular at higher magnetic<br />

fields, from SAR limitations. Focussing the field-of-view to a small inner volume reduces the number of required echoes considerably and thus ameliorates

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