TRADITIONAL POSTER - ismrm

Poster Sessions
cases on the pathological side and 6 on the healthy side. Conclusion: Probability maps and Gibbs tracking are superior to FACT. A higher specificity of
Gibbs cannot be shown at the moment.
2444. Probability Maps Compared to FACT Algorithm in Human Gliomas
Irina Mader 1 , Thao Nguyen Thanh 1 , Susanne Schnell 2 , Thomas Reithmeier 3 , Valerij G. Kiselev 2
1 Clinic for Neuroradiology, University Hospital Freiburg, Freiburg, Germany; 2 MR Physics, Department of Radiology, University
Hospital Freiburg, Freiburg, Germany; 3 Clinic for Stereotactic and Functional Neurosurgery, University Hospital Freiburg, Freiburg,
Germany
Problem: The importance of FACT algorithm for surgical planning has been substantiated in the past. No clinical experience is available for probability
maps. This work aimed to compare FACT and probability maps in human gliomas. Methods: 10 patients with human gliomas (4 WHO°II, 6 WHO°III)
received both fiber tracking methods of the motor fibers arising from fMRI derived seed points. Results: Probability maps were successful in all cases.
FACT failed in three cases with moderate to severe motor impairment. Conclusion: Probability maps seem to be superior to FACT, especially in cases with
strong fiber deviations and present oedema.
2445. Trimodal Imaging and Brain Plasticity: MR Diffusion Tensor Imaging Supplements Simultaneously
Acquired FET-PET and MP-RAGE of Human Brain Tumour Imaging
N. Jon Shah 1,2 , Irene Neuner 1,2 , Joachim Bernhard Maria Kaffanke 1 , Yuliya Kupriyanova 1 , Karl-Joseph
Langen 1 , Hans Herzog 1
1 Institute of Neurosciences and Medicine 4, Medical Imaging Physics, Forschungszentrum Jülich GmbH, 52425 Juelich, Germany;
2 Faculty of Medicine, Department of Neurology, RWTH Aachen University, 52074 Aachen, Germany
PET imaging is well established for the diagnosis of brain tumours. Its metabolic specificity delivers valuable information about the malignancy and the
extent of tumour tissue. Tumour growth forces the brain to reorganize itself to compensate for the lost areas. It has been shown that DTI is a valuable tool to
demonstrate the plasticity of the brain and it therefore offers information about the reorganization caused by tumour growth as well as surgical intervention.
The acquisition of trimodal PET, MP-RAGE and DTI data on an MR-PET hybrid scanner, capable of simultaneous MR and PET, to investigate plasticity
and reorganisation in human brain tumours is demonstrated.
2446. Comparison of Electrophysiologic Connectivity with Imaging Connectivity from DWI and Resting
State FMRI
Stephen Edward Jones 1 , Andreas Alexopolous, Erik Beall, Joanna Fong, Jorge Gonzalez-Martinez, Mark
Lowe, Blessy Mathew, Dileep Nair, Imad Najm, Michael Phillips, Kenneth Sakaie
1 Neuroradiology, Cleveland Clinic, Cleveland, OH, United States
We present a comparison of in-vivo connectivity scores: one derived from electrophysiology (EP) signals in human brains monitored with parenchymal
electrodes (for epilepsy workup); and the other from imaging connectivity methods such as HARDI and resting state fMRI. Assuming EP represent a gold
standard of connectivity, this provides a validation of various connectivity scores derived from MRI.
2447. Pre-Surgical Mapping Using Magnetoencephalography and Diffusion Tensor Tractography Reveals a
Case of Neuroplasticity
Nadia CF Scantlebury 1 , William Gaetz 2 , Elysa Widjaja, James Rutka 3 , Eric Bouffet 4 , Conrad Rockel 1 , Don
Mabbott 1
1 Program in Neuroscience and Mental Health, The Hospital for Sick Children, Toronto, Ontario, Canada; 2 Biomagnetic Imaging
Laboratory, Children's Hospital of Philadelphia, Philadelphia, PA; 3 Neurosurgery, The Hospital for Sick Children;
4 Haemotology/Oncology, The Hospital for Sick Children
We used combined magnetoencephalography (MEG) and Diffusion Tensor Imaging (DTI) tractography methods to delineate the cortico-spinal tracts (CSTs)
of an 11-year old female who presented with an arteriovenous malformation (AVM). Concurrent MEG-DTI techniques revealed a case of cerebral
plasticity, whereby motor function of the patient remained intact despite the contra-lateral displacement of her CST by the AVM. These data support the use
of the functional activation as a seed for launching neural tracts during pre-surgical evaluation in children. Moreover, these findings demonstrate that using
a concurrent MEG-DTI approach to delineate CSTs is invaluable when evaluating plasticity in the developing brain.
2448. Role of FMRI and DTI in Assessing the Efficacy of Visual Neurorehabilitation. Preliminary Data
Matteo Bendini 1 , Ingrid Inches 1 , Marissa Barabas 2 , Massimo Prior 3 , Monica Ronzon 1 , Stefano Curtolo 1 ,
Davide Canonico 4 , Carlo Alberto Marzi 2 , Francesco Di Paola 1
1 Neuroradiology Department, Ca' Foncello Hospital Treviso, Italy, Treviso, Italy; 2 Department of Neurological and Vision Sciences,
University of Verona, Italy; 3 Faculty of Psychology, University of Padua, Italy; 4 Department of Physics, Ca' Foncello Hospital
Treviso, Italy
Aim: Establish if f-MRI and DTI are valid (objective) tools to evaluate postchiasmatic damage. Materials and methods: 7 patients with HVFDs underwent
to a neuro-psycological evaluation. A f-MRI and DTI sequences were applied to study the visual activation and the optic radiation. Two patients underwent
to a visual rehabilitation treatment. Results: In all patients did not show an activation in the visual cortex ipsilateral to the injury. The contralateral visual
area showed a normal pathway of activation. In the two patients treated, higher activation in the contralateral visual areas was observed. Conclusions: F-MRI
and DTI are valid tools to study HVFDs.