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Poster Sessions<br />

MRI of Conductivity<br />

Hall B Thursday 13:30-15:30<br />

2864. Propagating RF Phase: A New Contrast to Detect Local Changes in Conductivity<br />

Astrid L.H.M.W. van Lier 1 , Alexander J. Raaijmakers 1 , David O. Brunner 2 , Dennis W.J. Klomp 3 , K. P.<br />

Pruessmann 2 , Jan J.W. Lagendijk 1 , Cornelis A.T. van den Berg 1<br />

1 Radiotherapy, UMC Utrecht, Utrecht, Netherlands; 2 Institute for Biomedical Engineering, ETH Zurich, Zurich, Switzerland;<br />

3 Radiology, UMC Utrecht, Utrecht, Netherlands<br />

From basic EM (electromagnetic) theory we know that the wavelength, thus the propagating phase, depends on the permitivity and conductivity. Analysis,<br />

based on simulations, showed that local changes in the conductivity, have the largest effect on the propagating phase in the physiological range. We<br />

demonstrated that it is possible to measure the effect both in phantoms and in vivo, with results comparable to results of EM simulations. This new contrast<br />

mechanism might be useful for the detection of conducting malignancies, such as breast tumours.<br />

2865. In Vivo Quantitative Conductivity Imaging Based on B1 Phase Information<br />

Tobias Voigt 1 , Ulrich Katscher 2 , Olaf Doessel 1<br />

1 Institute of Biomedical Engineering, University of Karlsruhe, Karlsruhe, Germany; 2 Philips Research Europe, Hamburg, Germany<br />

In this work, in vivo conductivity values of human tissue are obtained using standard MRI. Conductivity is a new and quantitative contrast for MRI. It can be<br />

obtained in 3D within 5 min by means of phase-based reconstruction presented in this abstract. Phase-based reconstruction is motivated analytically and<br />

validated in FDTD simulations and in in vivo experiments.<br />

2866. Estimation of the Anisotropy of Electric Conductivity Via B1 Mapping<br />

Ulrich Katscher 1 , Tobias Voigt 2 , Christian Findeklee 1<br />

1 Philips Research Europe, Hamburg, Germany; 2 Institute of Biomedical Engineering, University of Karlsruhe, Karlsruhe, Germany<br />

Electric conductivity might be used as diagnostic information due to its ability to reflect the grade of tissue damage. In general, the conductivity is given by a<br />

tensor including anisotropic cases of conductivity, as can be found in vivo in tissue with preferred cell direction like muscles or nerves. Measuring<br />

conductivity, characterizing the underlying cell structure, might increase diagnostic information. The recently presented “Electric Properties Tomography”<br />

(EPT) is able to determine tissue conductivity in vivo by post-processing B1 maps. This study demonstrates the ability of EPT to estimate also the anisotropy<br />

of the conductivity using an electrically anisotropic phantom.<br />

Parallel Imaging<br />

Hall B Monday 14:00-16:00<br />

2867. Title: Reconstruction of Sparsely-Sampled Dynamic MRI Data Using Iterative “Error Energy” [1]<br />

Reduction<br />

Sumati Krishnan 1 , David Moratal 2 , Lei-Hou Hamilton 3 , Senthil Ramamurthy 4 , Marijn Eduard Brummer 4<br />

1 Emory University, Atlanta, GA, United States; 2 2Universitat Politècnica de València, Valencia, Spain; 3 Georgia Institute of<br />

Technology, Atlanta, GA, United States; 4 Emory University, Atlanta, GA, United States<br />

A well-known reconstruction method, based on “error energy” reduction [1], is adapted to sparsely sampled dynamic cardiac MRI. Inherent temporally<br />

band-limited properties of known static regions in the FOV, are used to recover additional resolution from information embedded in the acquired k-t<br />

samples. The algorithm converges as the error due to residual dynamic content in the static region is minimized. Reconstructions equivalent to direct matrixinversion<br />

[2] are achieved with significantly reduced computational costs, while convergence properties are related to the sampling patterns. The proposed<br />

iterative method has potential applications for a variety of non-Cartesian grids as well as sparse-sampling patterns.<br />

2868. Null Space Imaging: A Novel Gradient Encoding Strategy for Highly Efficient Parallel Imaging<br />

Leo Tam 1 , Jason Peter Stockmann 1 , Robert Todd Constable, 12<br />

1 Biomedical Engineering, Yale University, New Haven, CT, United States; 2 Diagnostic Radiology & Neurosurgery, Yale University,<br />

New Haven, CT, United States<br />

Null Space Imaging (NSI) defines nonlinear encoding gradients to complement the spatial localization abilities of a parallel receiver array. To complement<br />

coil sensitivities, gradients should encode where coil sensitivities poorly distinguish signal. The singular value decomposition analyzes coil sensitivities to<br />

generate a complete basis set of vectors spanning the null space of sensitivities. By interpreting the orthogonal vectors in the null space as a complementary<br />

gradient set, NSI enables highly accelerated (R=16) parallel imaging as demonstrated by simulated spin echo experiments. NSI suggest complementary<br />

gradient design is a powerful concept for parallel imaging requiring only a limited set of receivers.<br />

2869. GPU Accelerated Iterative SENSE Reconstruction of Radial Phase Encoded Whole-Heart MRI<br />

Thomas Sangild Sørensen 1 , Claudia Prieto 2 , David Atkinson 3 , Michael Schacht Hansen 4 , Tobias<br />

Schaeffter 2<br />

1 Aarhus Univeristy, Aarhus N, Denmark; 2 King's College London; 3 University College London; 4 National Institutes of Health<br />

Isotropic whole-heart imaging has become an important protocol in simplifying cardiac MRI. The acquisition time can however be a prohibiting factor. To<br />

reduce acquisition times a 3D scheme combining Cartesian sampling in the readout direction with radial sampling in the phase encoding plane was recently<br />

suggested. It allows high undersampling factors in the phase encoding plane when obtaining data with a 32-channel coil array and employing non-Cartesian

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