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Poster Sessions<br />

2838. Electromagnetic and Thermal Simulations of Experimentally-Verified B1 Shimming Scheme with<br />

Local SAR Constrains<br />

Lin Tang 1 , Tamer S. Ibrahim 2<br />

1 School of Electrical and Computer Engineering, University of Oklahoma; 2 Departments of Bioengineering and Radiology, Univeristy<br />

of Pittsburgh, Pittsburgh, PA, United States<br />

In this work, using 3D numerical simulations and verifications with a 7T scanner equipped with a transmit array system we conduct a comprehensive study<br />

using B1 shimming for potential 7T whole-body applications. Different from previous works [2], this study includes the optimizations of the B1+ field,<br />

local/average SAR and the resulting temperature elevation in the tissue.<br />

2839. Simulation and Comparison of B1+ Mapping Methods at 3T<br />

Christopher Thomas Sica 1 , Zhipeng Cao 1 , Sukhoon Oh 1 , Christopher M. Collins 1<br />

1 Penn State College of Medicine, Hershey, PA, United States<br />

RF inhomogeneity greatly affects the quality of MR imaging at high field strength, and compensation methods typically require accurate B1+ maps for<br />

optimum performance. Comparison of B1+ mapping methods based on experimental results alone is limited by lack of knowledge of the true B1+ field<br />

distribution. MRI simulation allows for comparison of the true, input B1+ field distribution with a simulated map. This study simulates AFI and a flip angle<br />

series method at 3T, utilizing MRI and electromagnetic field simulations. The simulation maps correspond closely to the input B1+ and one another.<br />

Experimental maps deviate significantly from one another.<br />

B1 Mapping<br />

Hall B Tuesday 13:30-15:30<br />

2840. 3D Phase Sensitive B1 Mapping<br />

Steven Paul Allen 1 , Glen R. Morrell 2 , Brock Peterson 1 , Daniel Park 1 , Josh Kaggie 2 , Ernesto Staroswiecki 3 ,<br />

Neal K. Bangerter 1<br />

1 Department of Electrical and Computer Engineering, Brigham Young University, Provo, UT, United States; 2 Department of<br />

Radiology, University of Utah, Salt Lake City, UT, United States; 3 Department of Radiology, Stanford University, Stanford, CA,<br />

United States<br />

Accurate quantification of tissue sodium concentration is an important component of several potential applications of sodium MRI. Quantitative analysis of<br />

sodium concentrations requires accurate measurement of B1. However, the low SNR typical in sodium MRI makes accurate B1 mapping in a reasonable<br />

time challenging. Phase-sensitive B1 mapping techniques are particularly robust in low SNR environments. In this work, we apply phase sensitive B1<br />

mapping to sodium MRI, and compare it to a standard dual angle B1 mapping method. The phase sensitive method is shown to perform much better than<br />

the dual angle method, allowing rapid acquisition of reliable sodium B1 maps.<br />

2841. Image Inhomogeneity Correction in Human Brain at High Field by B 1 + and B 1 - Maps<br />

Hidehiro Watanabe 1 , Nobuhiro Takaya 1 , Fumiyuki Mitsumori 1<br />

1 Environmental Chemistry Division, National Institute for Environmental Studies, Tsukuba, Ibaraki, Japan<br />

We propose a correction method of image inhomogeneity at high field. The inhomogeneity is originated from B 1 - and measurable B 1 + . We confirmed that a<br />

ratio map of B 1 - to B 1 + (ρ) has a similar spatial pattern throughout human various brains from experimental results. The ratio map ρ in human brain was<br />

calculated from B 1 + maps and images obtained with adiabatic pulses. Then, B 1 - was calculated by ρ× B 1 + . Homogeneous intensity was achieved in the<br />

corrected images by B 1 + and B 1 - . Water fractions in gray and white matters obtained from corrected M 0 image were in good agreement with reported values.<br />

2842. Signal to Noise Ratio Analysis of Bloch-Siegert B 1 + Mapping<br />

Mohammad Mehdi Khalighi 1 , Laura I. Sacolick 2 , Brian K. Rutt 3<br />

1 Applied Science Lab, GE Healthcare, Menlo Park, CA, United States; 2 Imaging Technologies Lab, General Electric Global Research,<br />

Garching b. Munchen, Germany; 3 Department of Radiology, Stanford University, Stanford, CA<br />

The Bloch-Siegert method (BS) has been recently introduced as a fast, robust and accurate method for B 1 + mapping. To compare it with other existing<br />

methods, we derived analytical expressions for SNR in BS, Actual Flip Angle Imaging (AFI) and Double Angle (DA) B 1 + maps. Both theoretical and<br />

experimental comparisons show that the BS method has a higher SNR at low flip angles than the other methods, despite the shorter scan time of the BS<br />

method, making it a promising choice for B 1 + mapping for parallel transmit pulse design, especially in situations where there is highly non-uniform B 1<br />

+<br />

across the object.<br />

2843. Sa2RAGE - A New Sequence for Rapid 3D B 1 + -Mapping with a Wide Sensitivity Range<br />

Florent Eggenschwiler 1 , Arthur Magill 1,2 , Rolf Gruetter 1,3 , José P. Marques 1,2<br />

1 EPFL, Laboratory for Functional and Metabolic Imaging, Lausanne, Vaud, Switzerland; 2 University of Lausanne, Department of<br />

Radiology, Lausanne, Vaud, Switzerland; 3 Universities of Geneva and Lausanne, Department of Radiology, Switzerland<br />

Sa2RAGE is based on the rapid acquisition of two images with low flip angles just before and after a saturation pulse. The ratio of the signals from the<br />

images can be linked to a specific B 1 + . Optimization of the sequence parameters allowed the derivation of a protocol that performs 3D B 1 + -mapping in ~30s<br />

(matrix size 64x64x16) with limited T 1 dependence. Experimental work showed the accuracy of the B 1 + -mapping over a 10 fold range of B 1 + . In-vitro and invivo<br />

B 1 + maps were performed to demonstrate the applicability of the method on the context of parallel transmission.

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