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Poster Sessions<br />

1437. Realtime Cine MRI in Mice with a Single-Shot EPI Sequence and the Karhunen–Loeve Transform<br />

Guangping Dai 1 , Yu Ding 2 , Shuning Huang 1 , Orlando P. Simonetti 2 , David E. Sosnovik 3<br />

1 Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School; 2 Dorothy M. Davis Heart and<br />

Lung Research Institute, The Ohio State University; 3 Martinos Center for Biomedical Imaging, Massachusetts General Hospital,<br />

Harvard Medical School, Boston, MA, United States<br />

Realtime cine MRI of the mouse heart is reported using a single-shot EPI sequence and the Karhunen–Loeve transform. The entire mouse heart can be<br />

imaged with this technique in less than 5 minutes, using minimal sedation. This report demonstrates the ability of MRI to be used for high-throughput<br />

applications, and compete with echocardiography, in the basic science as well as and clinical settings.<br />

1438. Inflow Inversion Recovery MR Angiography of Renal Arteries at 3.0 T: A Feasibility Study<br />

Hiromitsu Onishi 1 , Tonsok Kim 1 , Masatoshi Hori 1 , Takahiro Tsuboyama 1 , Atsushi Nakamoto 1 , Hiroki<br />

Higashihara 1 , Mitsuaki Tatsumi 1 , Kaname Tomoda 1 , Mitsuhiro Uike 2 , Shoji Nakagami 2<br />

1 Department of Radiology, Osaka University Graduate School of Medicine, Suita, Osaka, Japan; 2 MR Sales & Marketing Department,<br />

GE Healthcare Japan, Hino, Tokyo, Japan<br />

The aim of the present study was to evaluate the feasibility of noncontrast MR angiography of the renal arteries using an Inflow Inversion Recovery (IFIR)<br />

sequence in healthy volunteers at 3.0 T. In nine of 10 cases, MR angiography with excellent image quality was obtained and both sides of renal arteries were<br />

finely delineated including peripheral branches. In four of 10 cases, two left renal arteries were observed. In addition, in one of four, two right renal arteries<br />

were also observed. The renal arteries were finely delineated by means of noncontrast MR angiography using an IFIR sequence at 3.0 T.<br />

1439. 3D Isotropic Non-Contrast Approach for the Assessment of Carotid Arteries Stenosis at 3T<br />

Ravi Teja Seethamraju 1 , Michael Jerosch-Herold 2 , Yiu-Cho Chung 3 , Peter Libby 4 , Marcelo F. Di Carli 5 ,<br />

Raymond Y. Kwong 6<br />

1 MR R and D, Siemens Medical Solutions, USA Inc., Charlestown, MA, United States; 2 Radiology, Brigham and Women's Hospital,<br />

Boston, MA, United States; 3 MR R and D, Siemens Medical Solutions, USA Inc., Columbus, OH, United States; 4 Cardiovascular<br />

Medicine, Brigham and Woman's Hospital, Boston, MA, United States; 5 Nuclear Medicine, Brigham and Women's Hospital, Boston,<br />

MA, United States; 6 Cardiovascular Imaging, Brigham and Women's Hospital, Boston, MA, United States<br />

We present MPRAGE and SPACE as two isotropic 3D non contrast techniques for the measurement of coronary artery stenosis. While both techniques<br />

provide precise measurements of the stenosis, they complement each other with respect to characterization of plaque.<br />

1440. Non-Contrast Time-Resolved MR Angiography Combining Multiple IR and N-1 Subtraction Arterial<br />

Spin Labeling Technique<br />

Tokunori Kimura 1 , Shinichi Kitane 2 , Kazuhiro Sueoka 3<br />

1 MRI Systems Development Department, Toshiba Medical Systems , Otawara, Tochigi, Japan; 2 MRI Systems Development<br />

Department, Toshiba Medical Enginieering, Otawara, Tochigi, Japan; 3 MRI Systems Development Department, Toshiba Medical<br />

Enginieering, Otawara, Tochigi, Japan<br />

In-flow time-resolved MR angiography technique employing non-subtraction arterial spin labeling with multiple IR (mIR) technique was proposed. It was,<br />

however, difficult for mIR to suppress background tissue of wide range of T1 values from fat to CSF. We proposed alternative N-1 subtraction technique<br />

further to suppress background tissue signals while minimizing extra acquisition time. Volunteer brain study was performed on 1.5T imager with 2 mIR<br />

pulses designed to suppress brain tissues. Resulting background signals of fat and brain parenchyma were well suppressed only by adding extra acquisition<br />

time of 16 sec for base image then subtraction.<br />

SAR & Safety<br />

Hall B Tuesday 13:30-15:30<br />

1441. Evaluation of Maximum Local SAR for Parallel Transmission (PTx) Pulses Based on Pre-Calculated<br />

Field Data Using a Selected Subset of "Virtual Observation Points"<br />

Matthias Gebhardt 1 , Dirk Diehl 2 , Elfar Adalsteinsson 3 , Lawrence L. Wald 4 , Gabriele Eichfelder 5<br />

1 Siemens Healthcare, Erlangen, Germany; 2 Siemens Corporate Technology, Erlangen, Germany; 3 Electrical Engineering and<br />

Computer Science, Massachusetts Institute of Technology, Cambridge, MA, United States; 4 Martinos Center for Biomedical Imaging,<br />

Harvard University, Charlestown, MA, United States; 5 Applied Mathematics II, University of Erlangen-Nuremberg, Erlangen,<br />

Germany<br />

This work addresses the complexity problem inherent in local SAR estimation for parallel transmission (pTx) and shows that a relatively small subset of<br />

carefully selected “virtual observation points” is adequate for prediction and control of maximum local SAR in pTx. We tested the proposed algorithm to<br />

detect local SAR maxima by comparison with an exhaustive search over local SAR distribution in numerical simulations of adult male and female subjects<br />

for an 8 channel whole body transmit array. The proposed method of model compression for local SAR successfully captured regions of local SAR maxima,<br />

but with dramatically reduced computation cost.

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