TRADITIONAL POSTER - ismrm

Poster Sessions
2334. The Inter-Scan Variations of Flow Quantifications on Human Basilar Artery: A Study Controlled the
Scan Conditions with Automatic Slice Positioning and the Automatic Lumen-Area Segmentation.
shiun-ying Ju 1 , Yu-Wei Tang 1 , Teng-Yi Huang 1 , Hsu-Hsia Peng 2
1 Department of Electrical Engineering, National Taiwan University of Science and Technology, Taipei, Taiwan; 2 Department of
Biomedical Engineering and Environmental Sciences, National Tsing Hua university, Hsinchu, Taiwan
The MR flow quantification of the vessels can be used to evaluate the response of the vessel-related surgeries. However, for the conventional longitudinal
studies of blood flow, manual slice selection in different days can cause measurement variation and thus degrade the accuracy of evaluation. In our study, in
order to solve this problem, an automatic slice positioning method combined with previously implemented automatic ROI selection method were proposed
to reduce the inter-scan variation. Furthermore, GPU-accelerated computation was applied to speed up the image registration. The flow variation of the
human study was reported.
2335. MRI Estimation of Global Brain Oxygen Consumption Rate
Varsha Jain 1 , Michael Langham 1 , Felix Wehrli 1
1 University of Pennsylvania, Philadelphia, PA, United States
The human brain is extremely sensitive and vulnerable to even small alterations in oxygen supply, making a measure for assessing global cerebral metabolic
rate of oxygen consumption (CMRO2) very important. We propose a method for estimating CMRO2 by simultaneous quantification of oxygen saturation by
MR oximetry and cerebral blood flow by phase-contrast MRI in the major vessels draining (superior sagittal sinus) and feeding the brain (internal carotid
and vertebral arteries), respectively. Our results demonstrate that the proposed technique is robust and reproducible, yielding temporally stable
measurements at a temporal resolution 30 seconds.
2336. Improved Image Contrast and Scan Efficiency for Fat Suppressed T1-Weighted Imaging at 3T with a
Spin Echo Two-Point Dixon Technique
Jingfei Ma 1 , Ken-Pin Hwang 2 , Ashok Kumar 3 , Lawrence Ginsberg 3
1 Department of Imaging Physics, University of Texas MD Anderson Cancer Center, Houston, TX, United States; 2 Applied Science
Lab, GE Healthcare Technologies, Houston, TX, United States; 3 Department of Diagnostic Radiology, University of Texas MD
Anderson Cancer Center, Houston, TX, United States
Inclusion of fat suppress (FS) pulses in a spin echo acquisition substantially reduces scan efficiency. At 3 Tesla, the incidental magnetization transfer and
dielectric effects from the FS pulses also degrade the image contrast and image uniformity. In this study, we developed a spin echo two-point Dixon
technique for fat-suppressed T1-weighted imaging. In comparison to the conventional spin echo with FS pulses, we demonstrated in vivo that the new
technique was 40% more efficient and had much better image contrast, better FS and overall image uniformity for fat-suppressed T1-weighted imaging of
head & neck at 3 Tesla.
2337. A Design of Head Holder for Calculation of Susceptibility Through Multiple Orientation Sampling
(COSMOS)
Hsiao-Wei Peng 1 , Chao-Chun Lin 2,3 , Yi-Jui Liu 1,4 , Chien-Kuo Chen 1 , Kuo-Fang Shao 4 , Wu-Chung Shen 2,5 ,
Hing-Chiu Chang 6,7
1 Department of Automatic Control Engineering, Feng Chia University, Taichung, Taiwan, Taiwan; 2 Department of Radiology, China
Medical University Hospital, Taichung, Taiwan; 3 Graduate Institute of Biomedical Electronics and Bioinformatics, National Taiwan
University, Taipei, Taiwan; 4 Master's Program in Biomedical Informatics and Biomedical Engineering, Feng Chia University,
Taichun, Taiwan; 5 School of Medicine, China Medical University, Taichung, Taiwan; 6 Applied Science Laboratory, GE Healthcare
Taiwan, Taipei, Taiwan; 7 Institute of Biomedical Electronics & Bioinformatics, National Taiwan University
We aimed to design a head holder for calculation the susceptibility through multiple orientation sampling (COSMOS). Different brain tissues with different
susceptibility result in the changes of focal magnetic fileds. Quantitative susceptibility imaging of brain are obtained by measurement of the focal magnetic
field changes.. It is a promising approach for exploring various brain pathological conditions. For clinical application, the challenging problem is to rotate
the head of patient along the Y axis only and fix the head in the degree through the MR scan. Our results show great control of the rotation in three axes with
the facilitation of head holder.
2338. A Study Specific Brain Template in MNI Space for an Aged Population with Aortic Stenosis
Ping Wang 1 , Elizabeth Strambrook 2 , Thomas Floyd 3
1 Radiology, University of Pennsylvania, Philadelphia, PA, United States; 2 Anesthesiology & Critical Care, University of
Pennsylvania, Philadelphia, PA, United States; 3 Anesthesiology & Critical Care, and Neurology, University of Pennsylvania,
Philadelphia, PA, United States
The MNI standard template is ideal for healthy subjects. To improve the accuracy of normalization and the further analysis (such as statistical analysis), we
created a study specific template in MNI space for an aged population with mild to critical aortic stenosis. This study specific template is approximately in
MNI template space, but accommodates some characteristics of this particular study population, especially incorporating the increased ventricular volume.
2339. Use of Opposed Shim Currents for Infold Reduction on a UHF MRI System with Head Gradient
Christopher John Wiggins 1 , Marion Caillat 1 , Denis Le Bihan 1 , Franz Schmitt 2 , Eva Eberlein 2
1 CEA/NeuroSpin, Gif-Sur-Yvette cedex, France; 2 Siemens AG, Healthcare Sector Imaging & IT Division, Magnetic Resonance,
Erlangen, Germany
The use of a head gradient set within a wholebody magnet can lead to significant artifacts. Signal arising from the shoulders is encoded in such a way that it
aliases into the main image. Such artifacts are particularly pronounced at higher field, where B1 effects cause the sensitive region of volume coils to extend
out into the chest and shoulder region. Previous approaches have tried to diminish the RF penetration in this area (through the use of RF shielding materials)
or to disrupt the local field through using ferromagnetic material shown into a jacket that the subject wears. This study shows that with the use of both the
wholebody and head gradient shim sets the signal from the shoulders could be dephased without affecting the signal from the head itself.