TRADITIONAL POSTER - ismrm

Poster Sessions
Myocardial Viability: Human Studies
Hall B Wednesday 13:30-15:30
1282. Non-Selective Double Inversion Recovery Pre-Pulse for Flow-Independent Black Blood Myocardial
Viability Imaging
Sarah Anne Peel 1 , Christian Jansen 1 , Geraint Morton 1 , Simon Duckett 1 , Tobias Schaeffter 1 , René M.
Botnar 1
1 Division of Imaging Sciences, King's College London, London, United Kingdom
MRI late gadolinium enhancement using the inversion-recovery sequence is the current gold standard for the assessment of myocardial viability. Although it
achieves high contrast between infarct and normal myocardium, there is often poor infarct-to-blood contrast. We sought to improve infarct-to-blood contrast
using a novel non-selective double inversion technique that provides flow-independent signal suppression over a wide user-defined T1-range. Simulations
and phantom studies demonstrate excellent tissue suppression over a wide T1-range. Preliminary patient data show an improvement in infarct-to-blood CNR.
This technique facilitates detection of sub-endocardial defects and has potential for more accurate quantification of infarct size and transmurality.
1283. Realtime Free-Breathing Ungated Imaging of Cardiac Function and Viability Using an IR-Spiral-SSFP
Sequence
Venkat Ramanan 1 , Labonny Biswas 1 , Jay Stephen Detsky 1 , Rhonda Walcarius 1 , Gideon A. Paul 1 , Alexander
J. Dick 1 , Graham A. Wright 1
1 Imaging Research, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada
Free-breathing, Ungated Realtime imaging using inversion recovery cartesian SSFP has been proposed to assess myocardial function and viability. However
since these techniques suffer from poor temporal resolution, we have designed Realtime IR-Spiral-SSFP to improve it. Several waveforms were designed
and tested resulting in different spatial and temporal resolutions. We scanned a few patients with a spiral waveform of 88ms temporal resolution and 3mm
spatial resolution. Preliminary results show that this is a viable imaging approach and there is scope for further improvement to improve the tradeoffs
between spatial vs temporal resolution.
1284. High Resolution MRI with a Spiral k-Space Trajectory: Atrial Wall Imaging and Late Gadolinium
Enhancement for the Assessment of RF Ablation Lesion Transmurality in the Left Atrium.
Benjamin R. Knowles 1 , Claudia Prieto 1 , Reza Razavi 1 , Tobias Schaeffter 1
1 Imaging Sciences, Kings College London, London, United Kingdom
Current late gadolinium enhancement (LGE) techniques for the visualisation of RF ablation lesions do not reach sufficient resolution to determine if ablation
lesions are transmural, We have formed a strategy to assess ablation lesion transmurality using the combination of high resolution LGE and atrial wall
imaging. Both MR scans use a spiral k-space trajectory as this trajectory is a highly efficient sampling scheme. Off-resonance effects are corrected for. Highresolution
LGE images are compared to the lower resolution Cartesian LGE currently in use. Thickness measurements of the atrial wall and of the enhancing
areas are conducted in order to assess transmurality.
1285. 3D Hybrid Radial Acquisition with Compressed Sensing for LGE Imaging of Left Atrium: A
Simulation Study
Ganesh Adluru 1 , Sathya Vijayakumar 1 , Nathan Burgon 2 , Eugene Kholmovski 1 , Nassir Marrouche 2 , Edward
DiBella 1
1 Radiology, University of Utah, Salt Lake City, UT, United States; 2 Cardiology, University of Utah, Salt Lake City, UT, United States
Atrial fibrillation currently affects over 7 million people in the U.S. and Europe. Late Gadolinium Enhancement (LGE) imaging offers a means to assess
ablation of the left atrium and the pulmonary vein ostia. Here we propose to reduce the scan time and improve the image quality over a standard 3D
Cartesian acquisition (with respiratory and ECG gating) by (i) acquiring data using a stack of stars scheme and (ii) using compressed sensing reconstruction
methods. Results from simulated phantom and patient data show the feasibility of the method to obtain better image quality that may improve clinical utility
of LGE imaging.
1286. Late Gadolinium Enhancement Can Visualize the Periinfarct Zone in Acute Myocardial Infarction
Yoshiaki Morita 1 , Naoaki Yamada 2 , Teruo Noguchi 3 , Hiromi Hashimura 2 , Tetsuro Nakazawa 2 , Atsushi
Kono 2 , Suzu Kanzaki 2 , Tetsuya Fukuda 2 , Masahiro Higashi 2 , Hiroaki Naito 2
1 Department of Radiology , National Cardiovascular Center , Suita, Osaka , Japan; 2 Department of Radiology, National
Cardiovascular Center, Suita, Osaka, Japan; 3 Division of Cardiology, National Cardiovascular Center, Suita, Osaka, Japan
Previous studies suggested that the periinfarct zone in acute myocardial infarction may provide the important prognostic information and serve as a
therapeutic target. It is widely known that the hyperintense area in T2-weighted imaging closely matched the periinfarct zone. However, T2-weighted image
is sometimes degraded by motion artifact and arrhythmia. In this study, we demonstrate that the early phase in late gadolinium enhancement (at the time of 2
minutes after gadolinium administration) can clearly visualize the periinfarct zone similar to or better than T2 map and offer robust diagnostic image quality
compared to T2-weighted image.