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Poster Sessions<br />

is possible to construct an adapted random sampling pattern by using measured k-space data as a reference, which automatically ensures an appropriate<br />

distribution of sample points for different types of scans. In this work, these sampling patterns were used in combination with regularized nonlinear inversion<br />

for parallel imaging. This allows the use of very high acceleration factors while still yielding images with excellent image quality.<br />

2877. Fast Non-Iterative JSENSE: From Minutes to a Few Seconds<br />

Feng Huang 1 , Wei Lin 1 , Yu Li 1 , Arne Reykowski 1<br />

1 Invivo Corporation, Gainesville, FL, United States<br />

It has been shown that joint image reconstruction and sensitivity estimation in SENSE (JSENSE) can improve image reconstruction quality when<br />

acceleration factor is high. However, existing methods for JSENSE need long reconstruction time and/or optimal termination condition, which have hindered<br />

its clinical applicability. In this work, a fast non-iterative JSENSE technique, based on pseudo full k-space, is proposed to improve the clinical applicability<br />

of JSENSE. Using the proposed method, the computation time for sensitivity maps could be reduced from minutes to a few seconds without degrading the<br />

image quality.<br />

2878. Parallel Imaging Using a 3D Stack-Of-Rings Trajectory<br />

Holden H. Wu 1,2 , Michael Lustig 2,3 , Dwight G. Nishimura 2<br />

1 Cardiovascular Medicine, Stanford University, Stanford, CA, United States; 2 Electrical Engineering, Stanford University, Stanford,<br />

CA, United States; 3 Electrical Engineering and Computer Science, University of California at Berkeley, Berkeley, CA, United States<br />

We present an efficient parallel imaging strategy for the 3D stack-of-rings non-Cartesian trajectory to further enhance its flexible trade-offs between image<br />

quality and scan time. Due to its distinct geometry, parallel imaging reconstruction for the 3D stack-of-rings trajectory can be decomposed directly into a<br />

series of 2D Cartesian sub-problems, which can be solved very efficiently. Experimental results demonstrate that a 2-fold reduction in scan time can be<br />

achieved on top of the 2-fold speedup already offered by the rings (compared to Cartesian encoding). Our approach combines the acceleration from both<br />

non-Cartesian sampling and parallel imaging in an efficient and easily deployable algorithm.<br />

2879. Coil-By-Coil Vs. Direct Virtual Coil (DVC) Parallel Imaging Reconstruction: An Image Quality<br />

Comparison for Contrast-Enhanced Liver Imaging<br />

Philip James Beatty 1 , James H. Holmes 2 , Shaorong Chang, Ersin Bayram, Jean H. Brittain 3 , Scott B.<br />

Reeder 4<br />

1 Applied Science Laboratory, GE Healthcare, Menlo Park, CA, United States; 2 Applied Science Laboratory, GE Healthcare,<br />

Waukesha, WI, United States; 3 Applied Science Laboratory, GE Healthcare, Madison, WI, United States; 4 Departments of Radiology<br />

and Medical Physics, University of Wisconsin-Madison, Madison, WI, United States<br />

Compared to coil-by-coil reconstructions, Direct Virtual Coil (DVC) parallel imaging reconstructions improve computational efficiency for high channel<br />

count coil arrays by only synthesizing unacquired data for one virtual coil instead of synthesizing a separate dataset for each physical coil. In this study,<br />

image quality is compared between coil-by-coil and DVC parallel imaging reconstructions in the context of contrast-enhanced liver imaging. Results<br />

showed no significant difference in the image quality achieved by the two reconstruction methods.<br />

2880. Towards a Geometry Factor for Projection Imaging with Non-Linear Gradient Fields<br />

Jason P. Stockmann 1 , Gigi Galiana 2 , Robert Todd Constable 3<br />

1 Biomedical Engineering, Yale University, New Haven, CT, United States; 2 Diagnostic Radiology, Yale University, New Haven, CT,<br />

United States; 3 Diagnostic Radiology, Neurosurgery, and Biomedical Engineering, Yale University, New Haven, CT, United States<br />

Conventional parallel imaging performance is assessed either by computing the analytical geometry factor or, if necessary, comparing the SNRs of fullysampled<br />

and undersampled Monte Carlo reconstructions. The empirical g-factor is unsuitable, however, for methods such as O-Space imaging in which<br />

non-linear gradients are used to obtain projections of the object. Since O-Space point spread functions are highly variable with position, the g-factor must<br />

be corrected for voxel-size in order to distinguish intra-voxel blurring from true noise amplification. This work shows the limited utility of uncorrected<br />

empirical g-factors for O-Space imaging and discusses how to compute the PSF for this class of non-linear projection imaging methods.<br />

2881. Selection of Image Support Region and of an Improved Regularization for Non-Cartesian SENSE<br />

Yoon Chung Kim 1 , Jeffrey Fessler 2 , Douglas Noll 1<br />

1 Biomedical Engineering, University of Michigan, Ann Arbor, MI, United States; 2 Electrical Engineering, University of Michigan,<br />

Ann Arbor, MI, United States<br />

Even though non-Cartesian parallel imaging has demonstrated increasing potential for an acquisition tool in MRI, there are still drawbacks such as reduced<br />

SNR and incomplete suppression of the undersampling or aliasing artifact. In suppressing such artifacts, the selection of image support, specifying a<br />

reconstruction region of interest is an important factor, due to the complex aliasing pattern associated with undersampling. Proper selection of image support<br />

can improve the conditioning of the reconstruction by constraining regions that are known to be zero. In this study, we investigate how the selection of<br />

image support region affects the performance of non-Cartesian SENSE reconstruction applied to undersampled spiral k-space data. Considering a potential<br />

effect of the sharp edges of a conventional mask on aliasing artifact, we also applied a smoothed mask through an additional regularized term to give<br />

smoothness to the mask edges. We tested our hypotheses on masking effects with the simulation and in-vivo human data and our results show that using a<br />

moderate size of mask can improve the image quality and the smoothing the mask is effective in suppressing aliasing artifact. Functional MRI result also<br />

indicates that softening function further increases the number of activated pixels and tSNR, and reduces image domain error.<br />

2882. Variable-Density Parallel Imaging with Partially Localized Coil Sensitivities<br />

Tolga Çukur 1 , Juan Santos 1 , John Pauly 1 , Dwight Nishimura 1<br />

1 Department of Electrical Engineering, Stanford University, Stanford, CA, United States<br />

PILS is a very fast reconstruction method for both Cartesian and non-Cartesian sampling; however, it can suffer from residual aliasing artifacts when<br />

coupled with variable-density acquisitions. In this work, we propose an improved variable-FOV method that suppresses the aliasing artifacts, while

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