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Poster Sessions<br />

3049. On Motion Estimation and Compensation Baseline Estimations in Dynamic Imaging: A Comparative<br />

Study with Cine Cardiac and Contrast-Enhanced Lung Imaging<br />

Mei-Lan Chu 1 , Jia-Shuo Hsu 1 , Hsiao-Wen Chung 1<br />

1 Graduate Institute of Biomedical Electronics and Bioinformatics, National Taiwan University, Taipei, Taiwan<br />

Estimation of the baseline is essential in compressed-sensing-based acceleration methods for MRI acquisition, as an accurate baseline estimation helps<br />

sparsifying the residues effectively. Recent literatures suggest improved baseline estimation using adaptive regularization or motion estimation (ME) and<br />

compensation (MC). While the suitability of these methods on other dynamic images with fast-varying contrast and morphology such as dynamic contrastenhanced<br />

(DCE) lung imaging have not been investigated. Therefore, the purpose of this study is to explore the baseline estimation performance of the<br />

block-matching and the phase-correlation ME/MC on both cine cardiac and DCE lung imaging, in comparison with the conventional approach.<br />

3050. Simple Self-Gating for Compensation of Respiratory Motion Using a Spiral K-Space Trajectory<br />

Rafael Luis O'Halloran 1 , Murat Aksoy 1 , Tobias Kober 2 , Roland Bammer 1<br />

1 Department of Radiology, Stanford University, Stanford, CA, United States; 2 Laboratory for functional and metabolic imaging, Ecole<br />

Polytechnique Fédérale de Lausanne, Lausanne, Switzerland<br />

A simple method of respiratory monitoring using the phase of the DC term of k-space collected with a spiral k-space trajectory is presented and compared<br />

with the measurement from the respiratory bellows. The method presented is shown to be in excellent agreement with the measurement from the respiratory<br />

bellows and reveal even cardiac pulsatility. In this work the method is used to gate a spiral-trajectory scan of the liver. The image reconstructed with the DC<br />

phase used for gating was qualitatively similar to the one reconstructed using conventional gating. Since the image data is used for gating no additional<br />

navigators must be acquired.<br />

3051. Methodology for Robust Motion Correction of Complex-Valued MRI Time Series<br />

Andrew Hahn 1 , Daniel Rowe 2<br />

1 Biophysics, Medical College of Wisconsin, Milwaukee, WI, United States; 2 Mathematics, Statistics, and Computer Science,<br />

Marquette University, Milwaukee, WI<br />

In functional MRI, subject motion during the acquisition of an image series can confound results and is generally corrected for using a variety of methods.<br />

Because statistical models for performing complex-valued fMRI analysis are available which can provide some benefits beyond the standard magnitude-only<br />

technique, investigation of a signal resulting from direct neuronal current involves complex-valued analysis, and recent reports have indicated potentially<br />

valuable functionally related phase signal, performing motion correction on complex-valued time series is of interest. This work identifies the problems<br />

facing motion correction of complex-valued images and proposes a solution for properly applying the correction.<br />

3052. Compensation for Nonrigid Motion Using B-Spline Image Registration in Simultaneous MR-PET<br />

Se Young Chun 1 , Sanghee Cho 1 , Tim G. Reese 2 , Bastien Guerin 1 , Xuping Zhu 1 , Jinsong Ouyang 1 , Ciprian<br />

Catana 2 , Georges El Fakhri 1<br />

1 Division of Nuclear Medicine & Molecular Imaging, Department of Radiology, Massachusetts General Hospital, Boston, MA, United<br />

States; 2 Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Boston,<br />

MA, United States<br />

This abstract reports preliminary results of motion corrected MR-PET reconstruction based on B-spline nonrigid image registration and compares it with<br />

HARP based motion compensation. With a breathing phantom, we collected MR and PET data simultaneously using BrainPET prototype PET scanner<br />

operating in the bore of a 3T TIM Trio scanner. Then we estimate the motion of a phantom using HARP and proposed B-spline based image registration<br />

with a novel invertibility penalty. These estimated motions were used in motion compensated iterative PET reconstruction. This preliminary result shows<br />

significant improvement of PET images for large motions.<br />

3053. Respiratory Motion Correction of PET Using Simultaneously Acquired Tagged MRI<br />

Timothy Gordon Reese 1 , Bastien Guérin 2 , Sanghee Cho 2 , Se Young Chun 2 , Jinsong Ouyang 2 , Xuping Zhu 2 ,<br />

Ciprian Catana 3 , Georges El Fakhri 2<br />

1 Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital , Boston , MA,<br />

United States; 2 Division of Nuclear Medicine & Molecular Imaging, Department of Radiology, Massachusetts General Hospital,<br />

Boston, MA, United States; 3 Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General<br />

Hospital, Boston, MA, United States<br />

As the spatial resolution of PET scanners improves, the deleterious effects of patient motion become an ever increasing limitation in PET studies. We<br />

present our first results with incorporating clinically relevant motion information derived from MR into the PET reconstruction process. We describe our<br />

current methods for tracking non-rigid periodic motion over the entire FOV of the MR-PET scanner, during the PET acquisition. All PET coincidences were<br />

reconstructed in a single frame while correcting the data for motion using MRI, demonstrating feasibility on an actual MR-PET system and a significant<br />

improvement in PET image quality.<br />

3054. DCE-MRI Non-Rigid Kidney Registration<br />

Michael Hofer 1 , Steven Keeling 2 , Gernot Reishofer 3 , Michael Riccabona 4 , Manuela Aschauer 3 , Rudolf<br />

Stollberger 1<br />

1 Institute of Medical Engineering, Graz University of Technology, Graz, Austria; 2 Institute for Mathematics and Scientific Computing,<br />

University of Graz, Graz, Austria; 3 Department of Radiology, Medical University of Graz, Graz, Austria; 4 Department of Pediatric<br />

Radiology, Medical University of Graz, Graz, Austria<br />

Dynamic contrast enhanced magnetic resonance imaging (DCE-MRI) is a very promising method for noninvasive assessment of renal function. To remove<br />

the influence of motion artifacts like breathing, a novel registration approach is proposed which derives a template image series with the underlying signal<br />

time course. This results in an independency from signal changes due to contrast media uptake. The original dynamic time series (source images) is then

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