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Poster Sessions<br />

2825. Focused Primary Tumour Staging and WB-MRI Distant Disease Assessment: A Potential All-In-One<br />

Staging Tool<br />

Martin D. Pickles 1 , Lindsay W. Turnbull 1<br />

1 Centre for MR Investigations, University of Hull, Hull, East Yorkshire, United Kingdom<br />

Oncology patients undergo multiple imaging investigations to stage their disease. The aim of this study was to investigate the feasibility of a focused primary<br />

tumour (breast or prostate) examination in combination with a WB-MRI for staging of distant disease. If successful we propose the addition of this technique<br />

could allow the omission of other examinations, such as radionuclide imaging, thereby streamlining the current imaging pathway. We conclude that focused<br />

primary tumour examinations in combination with a WB-MRI for staging of distant disease is feasible. However, the technique needs to validated in a much<br />

larger cohort than the one studied.<br />

2826. Imaging Characteristics of Metastasis in Whole Body Diffusion Weighted Imaging of Renal Clear Cell<br />

Carcinoma<br />

Jing Liu 1 , XiaoYing Wang 1 , XueXiang Jiang 1<br />

1 Department of Radiology, Peking University First Hospital, BeiJing, China<br />

The study aimed to explore the role of Whole-body DWI in clear cell renal cell carcinoma (RCC) and obtain the imaging characteristics of metastases. Ten<br />

patients with histologically confimed clear cell RCC and possible metastatic lesions were underwent standard Whole-body DWI, chest CT and routine MR<br />

examinations before chemotherapy. The results showed that the whole body DWI was very sensitive to the metastatic lesions in clear cell RCC and DWI<br />

showed its high rate of detection in pulmonary metastases. Whole body DWI had revealed great potential in metastatic screening of clear cell RCC.<br />

2827. Whole Body Imaging Multiparametric (T2/DWI/DCE) and Advanced Multimodality (PET/CT) for<br />

Detection of Recurrent Metastatic Cancer<br />

Michael A. Jacobs 1 , Li Pan 2 , Katarzyna J. Macura 1 , Thorsten Feiweier 3 , Wilhelm Horger 3 , Christine<br />

Lorenz 2 , Richard L. Wahl 1<br />

1 The Russell H. Morgan Department of Radiology and Radiological Science, The Johns Hopkins University School of Medicine,<br />

Baltimore, MD, United States; 2 Center for Applied Medical Imaging, Siemens Corporation, Corporate Research, Baltimore,, MD,<br />

United States; 3 Siemens AG, Healthcare Sector, Magnetic Resonance, Germany<br />

By using Whole Body MR and PET/CT approach to investigate metastatic disease can lead a better understanding of cancer aggressiveness. Functional<br />

imaging such as DWI/ADC, DCE-MR and 11C Choline PET is feasible and thus, combined DWI/ADC mapping, and PET/CT provides radiological<br />

biomarkers of molecular environment and could provide targets imaging treatment response.<br />

B1 +/- Mapping<br />

Hall B Monday 14:00-16:00<br />

2828. B1 Mapping of an 8-Channel TX-Array Over a Human-Head-Like Volume in Less Than 2 Minutes:<br />

The XEP Sequence<br />

Alexis Amadon 1 , Nicolas Boulant 1 , Martijn Anton Cloos 1 , Eric Giacomini 1 , Christopher John Wiggins 1 ,<br />

Michel Luong 2 , Guillaume Ferrand 2 , Hans-Peter Fautz 3<br />

1 Neurospin, CEA/DSV/I2BM, Gif-sur-Yvette, France; 2 IRFU, CEA/DSM, Gif-sur-Yvette, France; 3 Siemens Healthcare, Erlangen,<br />

Germany<br />

Efficient mitigation of the RF inhomogeneity using transmit coil arrays relies on the knowledge of the individual B1-maps. As the number of transmit<br />

channels increases, so does the acquisition time of all maps. Here we focus on a fast 2D sequence proposed by Fautz et al. which we adapt for multi-slice<br />

B1-mapping. We compare its results with that of the 3D AFI sequence on a spherical phantom surrounded by 8 transmit elements at 7T. We show<br />

comparable performance with a 12-fold increase in speed, making accurate B1-mapping of the human head feasible in 1.5 minutes for 8 transmit channels.<br />

2829. B1 Mapping with Whole Brain Coverage in Less Than One Minute<br />

Steffen Volz 1 , Ulrike Nöth 1 , Ralf Deichmann 1<br />

1 Brain Imaging Center (BIC), Goethe University Frankfurt, Frankfurt am Main, Germany<br />

There is great demand for fast B1 mapping techniques, e.g. for correction of quantitative T1 maps. However, most methods suffer from long experiment<br />

durations. The technique presented here is based on magnetization prepared FLASH imaging with specially designed preparation and excitation pulses to<br />

allow for multislice imaging, speeding up the acquisition. Systematic errors due to relaxation effects are avoided by intensity correction of individual k-space<br />

lines. The method allows for fast B1 mapping with whole brain coverage, an in-plane resolution of 4 mm, a slice thickness of 3 mm, and an accuracy of 2%<br />

within 46 s.<br />

2830. Fast RF Flip Angle Calibration by Bloch-Siegert Shift<br />

Laura Sacolick 1 , Ling Sun 2 , Mika W. Vogel 1 , Ileana Hancu 3<br />

1 GE Global Research, Garching b. Munchen, Germany; 2 GE Healthcare, Waukesha, WI, United States; 3 GE Global Research,<br />

Niskayuna, NY, United States<br />

Here we present a novel method for automated RF flip angle calibration based on the Bloch-Siegert shift. The Bloch-Siegert shift is an effect where spin<br />

resonance frequency shifts when an off-resonance RF field is applied. Two off-resonance RF pulses were added to a slice-selective spin echo sequence. The<br />

off-resonance pulses induce a phase shift in the acquired signal that is proportional to B12. The signal is spatially localized in two dimensions- by slice<br />

selection and readout filter, and the signal weighted average B1 over the slice is calculated. This calibration from a starting system transmit gain to measured

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