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Poster Sessions<br />

to monitor both the progress of the insertion and the procedure itself, such as core needle biopsy or tumor ablation. Flexibility was added to adjust the scan<br />

plane in real-time and make tradeoffs between update display rate and image quality.<br />

1840. A Passive, Image-Based Navigation Tool for Real-Time MR-Guided Percutaneous Interventional<br />

Procedures<br />

Wilhelm Strehl 1 , Eva Rothgang 1,2 , Wesley Gilson 2 , Klaus J. Kirchberg 3 , Joachim Hornegger 1 , Christine<br />

Lorenz 2<br />

1 Pattern Recognition Lab, Department of Computer Science, University of Erlangen-Nuremberg, Erlangen, Bavaria, Germany; 2 Center<br />

for Applied Medical Imaging, Siemens Corporation, Corporate Research, Baltimore, MD, United States; 3 Center for Applied Medical<br />

Imaging, Siemens Corporation, Princeton, NJ, United States<br />

Percutaneous interventions involve the navigation of a needle or probe to a target location. MRI is well-suited to guide these procedures as it offers good soft<br />

tissue target visualization and no ionizing radiation. High field wide bore MRI has stimulated interest in performing more of these procedures, but workflow<br />

and procedure speed are significant hurdles for full adoption. Here, a navigation tool for guiding and tracking the needle in real-time under MRI is<br />

presented.<br />

1841. Navigated Liver Biopsies in a Closed-Bore MR Scanner: First Clinical Experience<br />

Michael Moche 1 , Gregor Thörmer 1 , Nikita Garnov 1 , Jochen Fuchs 1 , Susann Heinig 1 , Tim Riedel 1 , Thomas<br />

Kahn 1 , Harald Busse 1<br />

1 Leipzig University Hospital, Leipzig, Germany<br />

MRI has been shown to be of great clinical utility for the guidance of various procedures. In a closed-bore scanner, the simplest approach is to manipulate<br />

the instrument outside the bore and move the patient inside for control imaging only. Potential benefits for percutaneous biopsies in the liver have been<br />

investigated in 15 patients by using a flexible add-on navigation solution which even allowed interventions in obese patients. Real time navigation was<br />

provided by following the virtual instrument on properly reformatted images of a 3D roadmap. In combination with a specific breathhold protocol, punctures<br />

could be reliably performed in reasonable times.<br />

1842. Evaluation of a Real Time MR-Guided Interactive Navigation Device: Phantom and Animal<br />

Experiments<br />

Steffi Valdeig 1 , Barry Fetics 2 , Li Pan, 1,3 , Clifford R. Weiss 1 , Erez Nevo 2 , Dara L. Kraitchman 1 , Frank K.<br />

Wacker 1<br />

1 Department of Radiology and Radiological Science, Johns Hopkins University, Baltimore, MD, United States; 2 Robin Medical Inc.,<br />

Baltimore, MD, United States; 3 Center for Applied Medical Imaging, Siemens Corporation, Corporate Research, Baltimore, MD,<br />

United States<br />

Purpose: To test the feasibility and accuracy of a tool that allows for interactive adjustments of the needle plane during a MR guided puncture Method:<br />

Experiments were performed in vivo and in phantoms using a gradient based navigation system for real time MR guided punctures in a wide bore MR<br />

imager. To assess for accuracy of the system the distance of the needle tip (virtual and real) to the target was determined on MR control scans. Result: The<br />

mean 3D total error was 4.9 ±2.8mm in the phantom. The system error was less than 2 mm. In the animal, successful punctures of the target structures could<br />

be confirmed in all punctures. Conclusion: The combination of image overlay with real time adjustment of the virtual needle and real-time imaging feedback<br />

provides an accurate and intuitive means to perform percutaneous interventions in a wide bore MR imager.<br />

1843. Fast and Precise: Real Time MR-Guided Prostate Biopsy at 3 Tesla in Animal Experiment.<br />

Patrik Zamecnik 1 , Axel j. Krafft 2 , Florian Maier 3 , Jaane Rauschenberg 2 , Michael Bock 2<br />

1 DKFZ German Cancer Research Center), Heidelberg, Baden-Württemberg, Germany; 2 DKFZ (German Cancer Research Center);<br />

3 DKFZ (German Cancer Resaerch Center)<br />

Real time MR-guided prostate biopsy at 3 Tesla in animal experiment proved to be a fast an precise method to perform prostate biopsies.<br />

1844. Development of a Pneumatic Robot for MRI-Guided Transperineal Prostate Intervention<br />

Sang Eun Song 1 , Nathan Bongjoon Cho 1 , Iulian Iordachita 2 , Gregory Scott Fischer 3 , Junichi Tokuda 4 ,<br />

Nobuhito Hata 4 , Gabor Fichtinger 5 , Clare Tempany 4<br />

1 Engineering Research Center, The Johns Hopkins University, Baltimore, MD, United States; 2 Department of Mechanical<br />

Engineering, The Johns Hopkins University, Baltimore, MD, United States; 3 Mechanical Engineering Department, Worcester<br />

Polytechnic Institute, Worchester, MA, United States; 4 Brigham and Women’s Hospital, Boston, MA, United States; 5 School of<br />

Computing,, Queen’s University, Kingston, Ontario, Canada<br />

As accurate needle positioning helps the prostate cancer detection and treatment, a number of MRI-compatible robots have been introduced. However,<br />

problems exist due to the strong magnetic field and limited workspace. Pneumatic actuator has the minimum distraction in the environment. However, it has<br />

poor controllability. To overcome the controllability problem, a simple external damping mechanism that can enhance accuracy was developed. Based on the<br />

actuator mechanism and workflow optimized modular design approaches, a new pneumatically actuated 4-DOF parallel robot for MRI-guided prostate<br />

intervention was developed. A preliminary evaluation was conducted with satisfying actuator average position error of 0.2mm.

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