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Poster Sessions<br />

Hardware optimization as well as sequence modification enable us to obtain heavily T2-weighted images at high-fields in tumor-bearing mice with in-plane<br />

resolution of 117μm and slice thickness of 1mm. Multi-slice datasets covering the entire thorax and abdomen are acquired in ~40 minutes.<br />

2902. ZOOM-PROPELLER-EPI: Non-Axial Imaging at Small FOV with PROPELLER-EPI<br />

Hing-Chiu Chang 1,2 , Chun-Jung Juan 3 , Yi-Jui Liu 4 , Chao-Chun Lin 2,5 , Hao Shen 6 , Tzu-Chao Chuang 7 ,<br />

Hsiao-Wen Chung 2<br />

1 Applied Science Laboratory, GE Healthcare Taiwan, Taipei, Taiwan; 2 Institute of Biomedical Electronics and Bioinformatics,<br />

National Taiwan University, Taipei, Taiwan; 3 Department of Radiology, Tri-Service General Hospital, Taipei, Taiwan; 4 Department<br />

of Automatic Control Engineering, Feng Chia University, Taichung, Taiwan; 5 Department of Radiology, China Medical University<br />

Hospital, Taichung, Taiwan; 6 Applied Science Laboratory, GE Healthcare, Beijing, China; 7 Electrical Engineering, National Sun Yatsen<br />

University, Kaohsiung, Taiwan<br />

Current implementation of PROPELLER-EPI exhibits difficulty in small FOV or non-axial acquisition due to the aliasing artifact along the phase-encoding<br />

direction of each blade. In this work, we propose a ZOOM-PROPELLER-EPI technique, which combines the reducing-FOV (rFOV) EPI to obtain sagittal<br />

images with a small FOV. We combined PROPELLER-EPI with three types of rFOV EPI technique based on inner volume excitation, both phantom and in<br />

vivo results demonstrated effectiveness of ZOOM-PROPELLER-EPI. The proposed method may find applications in non-axial high-resolution scans such as<br />

diffusion-weighted imaging of the cerebellum.<br />

Fat-Water Separation<br />

Hall B Wednesday 13:30-15:30<br />

2903. Quantification of Fatty Acid Compositions Using MR-Imaging and Spectroscopy at 3 T<br />

Pernilla Peterson 1 , Håkan Brorson 2 , Sven Månsson 1<br />

1 Medical Radiation Physics, Lund University, Malmö, Sweden; 2 Plastic and Reconstructive Surgery, Lund University, Malmö,<br />

Sweden<br />

This phantom study aims at investigating the potential of multi-echo imaging and spectroscopy to quantify the fraction unsaturated fatty acids (UF) and<br />

compare the results against known values. Six oil phantoms (UFs: 8%-92%) were measured in a 3T Siemens scanner with PRESS-localized spectroscopy<br />

and multi gradient echo sequences. Two fat resonances were separated from the acquired spectra using jMRUI and from multi-echo images using a linear<br />

least-squares approach. Both methods successfully quantified UFs with slopes/intercepts 0.886/3.80% and 0.956/11.3% for imaging and spectroscopy,<br />

respectively. This experiment successfully demonstrates the ability of multi-echo imaging and spectroscopy to evaluate fatty acid compositions.<br />

2904. Bipolar 3D-FSE-IDEAL: Fast Acquisition of Volumetric T 2 -Weighted Fat and Water<br />

Ananth J. Madhuranthakam 1 , Huanzhou Yu 2 , Ann Shimakawa 2 , Martin P. Smith 3,4 , Scott B. Reeder 5 , Neil<br />

M. Rofsky 3,4 , Charles A. McKenzie 6 , Jean H. Brittain 7<br />

1 MR Applied Science Lab, GE Healthcare, Boston, MA, United States; 2 MR Applied Science Lab, GE Healthcare, Menlo Park, CA,<br />

United States; 3 Radiology, Beth Israel Deaconess Medical Center, Boston, MA, United States; 4 Harvard Medical School, Boston, MA,<br />

United States; 5 Radiology, Medical Physics, Biomedical Engineering and Medicine, University of Wisconsin, Madison, WI, United<br />

States; 6 Medical Biophysics, University of Western Ontario, London, Ontario, Canada; 7 MR Applied Science Lab, GE Healthcare,<br />

Madison, WI, United States<br />

In this work, a bipolar acquisition with 3D-FSE-IDEAL is presented that reduces total scan time by acquiring all three images required for IDEAL<br />

processing in a single repetition. To eliminate phase errors that arise from alternating polarities of the readout gradients, a novel 2D phase correction method<br />

was implemented. High-resolution 3D T 2 -weighted images with uniform fat-water separation are demonstrated in breast and knee applications with less than<br />

5-minute acquisition times.<br />

2905. MR Water/Fat Separation Improves Optical Breast Imaging<br />

Colin Morehouse Carpenter 1 , Shudong Jiang 2 , Brian William Pogue 2 , Keith David Paulsen 2<br />

1 Radiation Oncology, Stanford University School of Medicine, Stanford, CA, United States; 2 Thayer School of Engineering at<br />

Dartmouth, Hanover, NH, United States<br />

IDEAL water/fat separation was used to improve hemoglobin quantification of MR-guided optical imaging. This technique is shown to reduce the cross-talk<br />

between oxyhemoglobin and water, caused by the spectral similarity of these tissue constituents in the near-infrared. It is demonstrated in gelatin phantoms<br />

that this approach reduces error in oxyhemoglobin by 70% on average for several cases. This finding has significant benefit for optical breast imaging, as the<br />

improved quantification provided by the MR water image can be leveraged to reduce the number of wavelengths in the optical data acquisition and thus<br />

increase temporal resolution.<br />

2906. Flexible and Efficient Data Acquisition Technique for 3D-FSE-IDEAL<br />

Ananth J. Madhuranthakam 1 , Huanzhou Yu 2 , Ann Shimakawa 2 , Martin P. Smith 3,4 , Scott B. Reeder 5 , Neil<br />

M. Rofsky 3,4 , Charles A. McKenzie 6 , Jean H. Brittain 7<br />

1 MR Applied Science Lab, GE Healthcare, Boston, MA, United States; 2 MR Applied Science Lab, GE Healthcare, Menlo Park, CA,<br />

United States; 3 Radiology, Beth Israel Deaconess Medical Center, Boston, MA, United States; 4 Harvard Medical School, Boston, MA,<br />

United States; 5 Radiology, Medical Physics, Biomedical Engineering and Medicine, University of Wisconsin, Madison, WI, United<br />

States; 6 Medical Biophysics, University of Western Ontario, London, Ontario, Canada; 7 MR Applied Science Lab, GE Healthcare,<br />

Madison, WI, United States<br />

FSE-IDEAL requires at least three echoes for uniform fat-water separation. The three echoes are commonly acquired in multiple repetitions. Recently,<br />

methods have been proposed to reduce total scan time by acquiring multiple gradient echoes in a repetition. Acquisition of a fourth echo increases the

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