TRADITIONAL POSTER - ismrm

Poster Sessions
distortion, we used a flat RF pulse which provides nearly constant signal intensity against the magnetic susceptibility and a gradient echo sequence. In the
result, it is shown that the signal loss in the orbitofrontal region of the brain is recovered without geometric distortion and Nyqust ghosts and the activation in
that region was analyzed successfully.
1101. Concurrent Transcranial Direct Current Stimulation (TDCS) and Functional MRI Reveals
Modulatory Effects on Brain Activation During a Simple Motor Task
Peter Dechent 1 , Rafael Polania 2 , Carsten Schmidt-Samoa 1 , Walter Paulus 2 , Andrea Antal 2
1 MR-Research in Neurology and Psychiatry, University Göttingen, Göttingen, Germany; 2 Department of Clinical Neurophysiology,
University Göttingen, Göttingen, Germany
Anodal/cathodal tDCS have facilitatory/inhibitory effects, respectively, on the stimulated cortical networks. Here we used concurrent tDCS-fMRI to test
whether anodal/cathodal tDCS result in BOLD-fMRI signal changes during a resting condition. Furthermore, we examined tDCS-effects on brain activation
during voluntary finger tapping. Anodal/cathodal tDCS over left M1 induced no detectable BOLD signal change. However, anodal/cathodal tDCS combined
with finger tapping resulted in a decreased BOLD response in SMA, but not M1, in comparison to voluntary finger tapping without stimulation. This
suggests that in contrast to the rest condition the combination of neuronal polarization and motor activation induces inhibition in remote brain areas.
1102. High-Resolution Fingersomatotopy at 7T Using HGS-Parallel Technique
SungDae Yun 1 , Jun-Young Chung 2 , Hyo Woon Yoon 3 , Zang-Hee Cho 3 , HyunWook Park 1
1 Department of Electrical Engineering, KAIST, Daejeon, Korea, Republic of; 2 Neuroscience Research Institute, Gachon University of
Medicine and Science , Incheon, Korea, Republic of; 3 Neuroscience Research Institute, Gachon University of Medicine and Science,
Incheon, Korea, Republic of
In a high field MRI, improvements in SNR and image quality are very noticeable, even though there are some drawbacks such as increased field
inhomogeneity and relatively short T 2 * . For EPI-based methods, these drawbacks are major challenges in performing fMRI. To reduce such problems, we
employed the HGS-Parallel technique as an fMRI imaging method which used the conventional gradient echo. This sequence is relatively robust to field
inhomogeneity and the T 2 * decay than the EPI. With the HGS-Parallel technique, we performed an fMRI experiment at a 7T for mapping the finger
somatosensory area in a high quality and resolution form.
1103. Effectiveness of Mental Imagery Strategy in Controlling an Activation of the Left Middle Frontal
Gyrus: Biofeedback Study Based on the Real-Time FMRI
Mikhail Zvyagintsev 1,2 , Yury Koush 3 , Miriam Dyck 3 , Klaus Mathiak 3
1 IZKF, RWTH Aachen University, Aachen, NRW, Germany; 2 Psychiatry, RWTH Aachen University, Aachen, NRW, Germany;
3 Psychiatry, RWTH Aachen University, Germany
Biofeedback based on a real-time fMRI is a promising tool especially in clinical research. In this study we show feasibility of controlling the left middle
frontal gyrus by using mental imagery strategy.
1104. Sensitivity and Spatial Specificity of Multiple Phase-Cycled Pass-Band BSSFP FMRI at 9.4T
Sung-Hong Park 1,2 , Tae Kim 1 , Ping Wang 1 , Timothy Q. Duong 2 , Seong-Gi Kim 1
1 Radiology, University of Pittsburgh, Pittsburgh, PA, United States; 2 Research Imaging Institute, Ophthalmology/Radiology,
University of Texas Health Science Center at San Antonio, San Antonio, TX, United States
We performed high-resolution pass-band bSSFP fMRI at multiple phase cycling angles on rat brain at 9.4T. Activation foci in fMRI maps shifted as a
function of phase cycling angle and the location of the foci was correlated with hyperintense regions in corresponding baseline transition-band bSSFP, some
of which were also correlated with cortical surface veins or intracortical veins. The results indicated that there is spatial heterogeneity in signal sources (T2
or T2*) of pass band bSSFP fMRI. Baseline transition band bSSFP could be used to predict outcomes of corresponding pass-band bSSFP fMRI maps.
1105. Interleaved TMS/CASL: State Dependence of Repetitive TMS Effects on the Dorsal Premotor Cortex
Marius Moisa 1 , Rolf Pohmann 1 , Hartwig Roman Siebner 2 , Axel Thielscher 1
1 Max Planck Institute for Biological Cybernetics, Tübingen, BW, Germany; 2 Danish Research Centre for Magnetic Resonance,
Copenhagen University Hospital Hvidovre, Copenhagen, Denmark
We have recently demonstrated the technical feasibility and the potential advantages of combining transcranial magnetic stimulation (TMS) with continuous
arterial spin labeling (CASL) imaging. Here, we use this novel approach to assess the effects of repetitive TMS applied to the left dorsal premotor cortex
(PMd) on rCBF (regional cerebral blood flow) during different motor states. The state-dependent effects of left PMd rTMS on rCBF, is in concordance with
previous results using BOLD imaging and a different task. As a next step, we will analyze the time dependence of the observed TMS effects across the
different experimental blocks of one run.
1106. Development of Simulator Training to Reduce Head Motion Artifact in FMRI
Shawn Ranieri 1,2 , Shaun Boe 3 , Fred Tam 1 , Lauren Gordon 4 , Tara Dawson 1 , Jon Ween 5 , William McIlroy 6 ,
Simon J. Graham 1,7
1 Rotman Research Institute, Baycrest Centre for Geriatric Care, Toronto, ON, Canada; 2 Institute of Biomaterials and Biomedical
Engineering, University of Toronto, Toronto, ON, Canada; 3 Toronto Rehabilitation Institute, Toronto, ON, Canada; 4 Faculty of Health
Sciences, Queen's University, Kingston, ON, Canada; 5 Kunin-Lunenfeld Applied Research Unit , Brain Health Complex, Toronto,
ON, Canada; 6 Department of Kinesiology, Faculty of Applied Health Sciences, University of Waterloo, Waterloo, ON, Canada;
7 Department of Medical Biophysics, University of Toronto, Toronto, ON, Canada
There has been a longstanding need to develop techniques that improve data quality in fMRI by suppressing motion artifact. Head motion exceeding a few
millimetres remains problematic and high interest participants including motor stroke patients often exceed this threshold. Here, a new technique is described
that attempts to reduce participant head motion through visual feedback training in an fMRI simulator. Results from three stroke patients show that simulator