TRADITIONAL POSTER - ismrm

Poster Sessions
2597. Dynamic Contrast-Enhanced MRI in the Liver at 3T with Dual-Input Pharmacokinetic Model
Analysis
Andrew Brian Gill 1 , Lorenzo Mannelli 1 , Peter Beddy 1 , Richard T. Black 1 , Ilse Joubert 1 , Andrew N. Priest 1 ,
Martin J. Graves 1 , David J. Lomas 1
1 Dept of Radiology, University of Cambridge & Addenbrooke's Hospital, Cambridge, Cambridgeshire, United Kingdom
This study reports hepatic perfusion measurements made with DCE-MRI at 3T, performed so as to allow analysis using a dual-input kinetic model which
separates perfusion components from the hepatic artery and portal vein. DCE data acquisition had a single-heartbeat time resolution and employed a dual
saturation-recovery sequence to sample high [Gd] in the blood near-simultaneously with low [Gd] in the liver parenchyma. Mean results for total perfusion
(69 ± 24 ml/min/100ml) and arterial fraction (16 ± 7 %) from 7 healthy volunteers were in line with those reported by other groups collecting data at 1.5T.
2598. Non-Contrast-Enhanced Hepatic MR Arteriography with Two-Dimensional Parallel Imaging and
Short Tau Inversion Recovery Methods to Shorten Acquisition Time Without Image Quality Deterioration
Hiroyoshi Isoda 1 , Kotaro Shimada, Tomohisa Okada, Shigeki Arizono, Toshiya Shibata, Kaori Togashi
1 Diagnostic Imaging and Nuclear Medicine, Kyoto University, Kyoto, Japan
To study whether shortening of acquisition time for selective hepatic artery visualization is feasible without image quality deterioration by adopting twodimensional
(2D) parallel imaging (PI) and short tau inversion recovery (STIR) methods. Shortening of the acquisition time for selective hepatic artery
visualization was feasible without deterioration of the image quality by combination of 2D-PI and STIR methods. It will facilitate using non-contrastenhanced
MRA in clinical practice.
2599. High Temporal Resolution 4D Contrast Enhanced Liver MR Imaging Using Spiral Trajectory and
Sliding Window Reconstruction
Bo Xu 1,2 , Pascal Spincemaille 2 , Beatriu Reig 2 , Fei Sun 3 , Martin R. Prince 2 , Yi Wang, 2,3
1 Department of Biomedical Engineering, Cornell University , Ithaca, NY, United States; 2 Department of Radiology, Weill Cornell
Medical College, New York, NY, United States; 3 Department of Biomedical Engineering, Cornell University, Ithaca, NY, United
States
In this work, high temporal resolution 4D dynamic contrast enhanced liver MR imaging is achieved using a stack of spirals trajectory and sliding window
reconstruction in healthy volunteers. This allows the detection and characterization of liver lesions in the arterial and later phases without the need for
accurate contrast bolus timing. Additionally, a retrospective selection of the optimal arterial phase is possible and the determination of hepatic artery
anatomical variants can be done with increased diagnostic confidence.
2600. Fat Fraction Measurement Using MFFE Sequence with T2* Correction and Little T1 Dependence:
Experience in Chronic Liver Disease Patients Before and After Gd-EOB-DTPA Enhancement
Kengo Yoshimitsu 1 , Tomoyuki Okuaki 2 , Shutaro Saiki 2 , Marc van Cauteren 2
1 Radiology, Faculty of Medicine, Fukuoka University, Fukuoka, Japan; 2 Philips Medical Systems, Tokyo, Japan
Newly developed mFFE can provide consistent fat fraction regardless of T2* or T1 alteration of the liver tissue as compared to conventional dFFE, and
therefore is particularly useful in evaluation of steatosis in chronic hepatitis C or non-alcoholic steatohepatitis patients, in whom considerable amount of iron
may also acculmulate in the liver.
2601. SWI-Based Method for Emphasizing Susceptivity Changes on Liver T2* Multi-Echo Gradient-Echo
MRI
Maria Filomena Santarelli 1,2 , Nicola Martini 2 , Vincenzo Positano, 12 , Alessia Pepe 2 , Daniele De Marchi 2 ,
Luigi Landini, 1,3 , Massimo Lombardi 2
1 Institute of Clinical Physiology, National Research Council (CNR), Pisa, Italy; 2 Tuscany Foundation "G. Monasterio", Pisa, Italy;
3 Information Engineering, EIT, University of Pisa, Pisa, Italy
A method is suggested, based on a SWI approach, that increases the contrast between tissues of different susceptivity, in liver T2* multi-echo gradient-echo
images.
2602. Assessment of Liver Iron Overload by Combining Fast T1-Mapping and T2*-Mapping
Christian Kremser 1 , Benjamin Henninger 1 , Stefan Rauch 1 , Heinz Zoller 2 , Wolfgang Vogel 2 , Werner
Jaschke 1 , Michael Schocke 1
1 Dept. of Radiology, Innsbruck Medical University, Innsbruck, Tyrol, Austria; 2 Department of Internal Medicine II, Innsbruck
Medical University, Innsbruck, Tyrol, Austria
The assessment of liver iron overload by means of magnetic resonance imaging is usually based on the quantification of T2* values. It was the purpose of
this study to investigate if a combination of T2* values and T1 values, obtained with a fast T1 mapping technique, could be beneficial for diagnosis.
2603. Whole Liver T 1 ,T 2 , and T 2 * Relaxation Mapping Using Echo Planar Imaging
Caroline L. Hoad 1 , Alexander G. Gardener 1 , Ji-Young Lim 1 , Carolyn Costigan 2 , Robin C. Spiller 3 , Penny
A. Gowland 1 , Luca Marciani 3 , Guru P. Aithal 3 , Susan T. Francis 1
1 School of Physics and Astronomy, University of Nottingham, Nottingham, Nottinghamshire, United Kingdom; 2 Brain and Body
Centre, University of Nottingham, Nottingham, Nottinghamshire, United Kingdom; 3 Nottingham Digestive Diseases Centre, NIHR
Biomedical Research Unit, University Hospitals NHS Trust, Nottingham, Nottinghamshire, United Kingdom
T 1 , T 2 and T 2 * relaxation maps of the whole liver of chronic liver disease patients were generated using respiratory triggered IR-SE-EPI, SE-EPI and GE-EPI
datasets respectively. These maps were used to generate voxel-by-voxel histograms of the liver tissue, the central peak data of the histogram being