TRADITIONAL POSTER - ismrm

Poster Sessions
2255. High Resolution 3D Intracranial Imaging at 3.0T
Yiu-Cho Chung 1 , Steven Shea 2 , Ye Qiao 3 , Orlando P. Simonetti 4 , Bruce Wasserman 3
1 Siemens Medical Solutions USA, Inc., Columbus, OH, United States; 2 Siemens Corporate Research, United States; 3 Johns Hopkins
University, United States; 4 The Ohio State University, United States Minor Outlying Islands
Intracranial artery imaging is usually done by 2DTSE. However, the technique has long scan time, and has very limited anatomical coverage. We propose
here the use of T1w-SPACE, a variant of TSE, for 3D imaging of the intracranial vessels. Using a 32 channel head coil at 3.0T, the technique achieves a
spatial resolution of (0.5mm)3, comparable to CT, in less than 11minutes. The technique can cover both sides of the tortuous ICA and MCA in one scan.
SNR comparison found that the 3D technique has consistently higher SNR than 2DTSE.
2256. Utility of Susceptibility Weighted Imaging for the Detection of Arteriovenous Shunting in Vascular
Malformations of the Brain
Bharathi Dasan Jagadeesan 1 , Josser E. Delgado Almandoz 2 , Tammie Benzinger 2 , Christopher Moran 2
1 Neuroradiology, Washington University School of Medicine , St Louis, MO, United States; 2 Neuroradiology, Washington University
School of Medicine, St Louis, MO, United States
We retrospectively evaluated the utility of susceptibility weighted imaging (SWI) in the detection of arterio-venous shunting (AVS) in 47 patients with 66
brain vascular malformations (BVM) identified on digital subtraction angiography (DSA). AVS was considered to be present if there was hyperintensity in a
vein adjacent to the BVM. Overall, SWI had a sensitivity of 93%, specificity of 100% and accuracy of 97% for the detection of AVS. In the 13 BVMs
associated with hemorrhage, SWI had sensitivity and specificity of 100%. In the 53 BVMs not associated with hemorrhage, SWI had a sensitivity of 92%
and specificity of 100%.
2257. Comparative Study of 3.0- And 1.5-T MR in the Follow-Up of Moyamoya Disease
Qianna Jin 1 , Tomoyuki Noguchi 1 , Hiroyuki Irie 1 , Masashi Nishihara 1 , Tetsuyoshi Hirai 1 , Masatou
Kawashima 2 , Toshio Matsushima 2 , Sho Kudo 1
1 Radiology, Saga University Hospital, Saga, Japan; 2 Neurosurgery, Saga University Hospital, Saga, Japan
To retrospectively compare 3.0- and 1.5-T magnetic resonance (MR) findings in patients with moyamoya disease (MMD), and assess the relationship and
difference between those two modalities in the follow-up of MMD. 60 (120 sides) MMD patients (15 male and 45 female patients, age range: 5 to 60 years,
post/pre-operative patients: 44/ 16) were included. We got different upgrading rate among one-year interval follow-up with 1.5- and 3.0-T MR in different
orders. Regardless of disease progressing, we should be careful about 1.5-T MR in evaluating steno-occlusive severity of intracranial vessels in MMD for its
higher overestimating rate compared with 3.0-T MR.
2258. Temporal Stability of Blood Flow Patterns in Cerebral Aneurysms Quantified with 2D Phase Contrast
Magnetic Resonance Imaging In-Vivo
Christof Karmonik 1 , Yi J. Zhang 1 , Orlando Diaz 2 , Richard Klucznik 2 , David Purdy 3 , Robert G. Grossman 1
1 Neurosurgery, The Methodist Hospital Neurological Institute, Houston, TX, United States; 2 Radiology, The Methodist Hospital
Neurological Institute, Houston, TX, United States; 3 Siemens Healthcare, Malvern, PA, United States
Complex flow patterns in cerebral aneurysms have been identified by computational fluid dynamics (CFD) studies to potentially be predictive of aneurysm
rupture. Here, we quantified the stability of blood flow patterns in cerebral aneurysms in vivo based on flow features in 2D pcMRI images in seven
aneurysms. A stability index (SI) defined as the area fraction (in percent) exhibiting sign changes of the through-plane velocity was calculated. Average SI
range was 1.3%-20.6%. Average SI and aneurysm size were linearly correlated (R=0.796). Further studies are warranted to explore the potential of the
average SI as a marker for aneurysm rupture.
2259. Measurement of Deep Gray Matter Perfusion in Acute Mild Traumatic Brain Injury Using Segmented
True-FISP ASL
Elan J. Grossman 1 , Yulin Ge 1 , Matilde Inglese 1 , Ke Zhang 1 , Jing An 2 , Ding Xia 1 , Jian Xu 3 , Niels
Oesingmann 3 , Kelly A. Mcgorty 1 , Joseph Reaume 1 , Robert I. Grossman 1 , Qun Chen 1
1 Center for Biomedical Imaging, Department of Radiology, NYU School of Medicine, New York, United States; 2 Siemens Medical
Solutions, Beijing, China; 3 Siemens Medical Solutions, Malvern, PA, United States
Conventional imaging fails to reveal evidence of damage in mild traumatic brain injury (MTBI) that accounts for its disabling impairments. The purpose of
the current study is to examine if perfusion changes in thalamus and basal ganglia can be a possible indicator of pathology in acute MTBI. We have
employed segmented True-FISP ASL, which we recently developed to measure perfusion in deep gray matter at high spatial resolution. Results indicate
there are significant differences between patients and controls in thalamus and caudate. This suggests these regions may exhibit hypoperfusion in acute
MTBI and could be biomarkers of persistent post-concussive syndrome.
2260. Complex Flow Patterns in a Real-Size Intracranial Aneurysm Phantom: A PC-MRI Study Compared
with PIV
Pim van Ooij 1 , Annetje Guédon 2 , Christian Poelma 3 , Joppe J. Schneiders 4 , Charles B. Majoie 4 , Jenny
Dankelman 2 , Ed vanBavel 1 , Aart J. Nederveen 4
1 Biomedical Engineering & Physics, Academic Medical Center, Amsterdam, Noord-Holland, Netherlands; 2 Biomechanical
Engineering, Delft University of Technology, Delft, Netherlands; 3 Laboratory for Aero and Hydrodynamics, Delft University of
Technology, Delft, Netherlands; 4 Radiology, Academic Medical Center
To validate 4D blood flow velocity measurements in intracranial aneurysms using phase contrast MRI, a real-size glass phantom of an intracranial aneurysm
was created and used for blood flow velocity measurements using PC-MRI and PIV. Resolution of PC-MRI was 0.5x0.5x0.5 mm and took 70 minutes to
scan. Both steady and pulsatile flow measurements in MRI and PIV produced similar flow patterns of similar magnitude, although more noise was found in