TRADITIONAL POSTER - ismrm

Poster Sessions
2654. Monitoring Random Molecular Diffusion and Tissue Perfusion in Rat Liver by Diffusion Weighted
Proton MRI
Beena George 1 , Andriy Babsky 1 , Navin Bansal 1
1 Radiology, Indiana University, Indianapolis, IN, United States
Diffusion weighted (DW) 1H MRI may be useful in the diagnosis of liver diseases. Fast and slow apparent diffusion coefficients (ADCfast and ADCslow,
respectively) were separated in the normal rat liver by using ten b values. After mortal ischemia, ADCfast disappeared, demonstrating that this component
results from microcapillary blood perfusion. ADCslow decreased after ischemia, most likely due to intracellular accumulation of water. DW 1H MRI can
provide information about tissue perfusion and molecular diffusion which are both important physiological parameters.
2655. Improved Robustness with a Stretched Exponential Model for Intravoxel Incoherent Motion (IVIM)
DW Signal
Yousef Mazaheri 1 , Daniel B. Rowe 2 , Jingbo Zhang 3 , Hedvig Hricak 3 , Jason A. Koutcher 1
1 Medical Physics, Memorial Sloan Kettering Cancer Center, New York, NY, United States; 2 Mathematics, Statistics, and Computer
Science, Marquette University, Milwaukee, WI, United States; 3 Radiology, Memorial Sloan Kettering Cancer Center, New York, NY,
United States
A stretched exponential model is presented to describe intravoxel incoherent motion (IVIM) signal. Simulations results show that the distributed diffusion
coefficient and á is a dimensionless “stretching” parameter have tolerable CV (