TRADITIONAL POSTER - ismrm

Poster Sessions
2016. The Hemodynamic Response Characteristics Underlying the Age-Related Change of Brain Activation
During Motor Execution
Toshiharu Nakai 1 , Makoto Miyakoshi 1 , Epifanio Bagarinao 1 , Chikako Nakai 2 , Kayako Matsuo 3
1 Functional Brain Imaging Lab, National Center for Geriatrics and Gerontology, Ohbu, Aichi, Japan; 2 School of Health Sciences,
Toyoshashi Sozo University, Toyohashi, Aichi; 3 Psychology, National Taiwan University, Taipei, Taiwan
The characteristics of the hemodynamic response function underlying the age-related change was investigated to estimate its contribution to the statistical
evaluation of fMRI by using motor tasks. It was suggested that the neuronal demanded was augmented to support cognitive processing for motor regulation
rather than motor execution itself. Augmented activation in the elderly subjects mostly depended on the increased BOLD signal amplitude between the initial
and post-stimulus peaks. It will be recommended to consider the potential bias induced by the non-linear dynamics of HRF to assess the age-related change
of brain activation.
2017. Differences in GABA to Creatine Ratio Between the Occipital and the Medial Pre-Frontal Cortices
Jan Willem W. van der Veen 1 , Paul J. Carlson 1 , Jun Shen 1
1 NIH, NIMH, MAP, Bethesda, MD, United States
GABA and Glx were measured in 28 volunteers using a PRESS-based two step J editing sequence. Two voxels located in the medial prefrontal cortex
(MPFC) and the occipital lobe (OCC) were studied. The GABA/Cre ratio was significantly higher (P