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Poster Sessions<br />

hippocampus and some volumetric reductions in the contiguous WM. These findings suggest that both regional GM atrophy and WM disconnection might,<br />

at least parially, explain cognitive deficits detectable in patients with OSAS.<br />

2418. Oral Tongue Squamous Cell Carcinoma Evaluated by PROPELLER and Echoplanar Diffusion-<br />

Weighted Imaging<br />

Chun-Jung Juan 1 , Hing-Chiu Chang 2,3 , Cheng-Yu Chen 1 , Hung-Wen Kao 1 , Chun-Jen Hsueh 1 , Chih-Wei<br />

Wang 1 , Cheng-Chieh Cheng 1,3 , Su-Chin Chiu 1,3 , Hsiao-Wen Chung 1,3 , Guo-Shu Huang 1<br />

1 Department of Radiology, Tri-Service General Hospital, Taipei, Taiwan; 2 Applied Science Laboratory, GE Healthcare Taiwan,<br />

Taipei, Taiwan; 3 Institute of Biomedical Electronics and Bioinformatics, National Taiwan University, Taipei, Taiwan<br />

In this study we aimed to verify the imaging quality of fast spin-echo PROPELLER diffusion weighted imaging (FSE-PROP-DWI) and echoplanar DWI<br />

(EP-DWI) in oral cavity and to investigate the apparent diffusion coefficient (ADC) of pathological proven oral tongue squamous cell carcinoma (OTSCC).<br />

Our results show that FSE-PROP-DWI is superior to EP-DWI with less imaging distortion and is satisfactory for measurement of ADC of OTSCC.<br />

2419. Improved Head and Neck Contrast Enhanced Imaging Using High Resolution Isotropic 3D T1<br />

SPACE: A Feasibility Study<br />

Magalie Viallon 1 , Karen Masterson 1 , Minerva Becker 1<br />

1 Radiologie, Hopital Universitaire de Genève, Geneva, Switzerland<br />

Post Gadolinium MR head and neck examinations remain challenging due to the need for a large anatomic coverage in minimum acquisition time. For<br />

cranial nerves and skull base investigation, 3D acquisitions are very useful not only to better visualize and analyze the nerves but also to provide large head<br />

and neck coverage of often extended or multi focal pathology. Until recently, 3D acquisitions implemented to image the head and neck area were based on<br />

gradient echo imaging kernel (T1 3D Vibe FS, T1 MP-RAGE. Unfortunately, fast 3D T1w gradient echo imaging is limited by the presence of air-tissue<br />

interfaces and inherent susceptibility artefacts. Nevertheless, to study the whole course of nerves and localize focal or global contrast enhancement, a fat<br />

saturated spin-echo 3D T1 sequence seems more adequate. We investigate here the utility of 3D T1 FS Space (Sampling Perfection with Application<br />

optimized Contrasts using different flip angle Evolutions) for head and neck imaging at 3T and its clinical relevance in various pathologies of this region.<br />

2420. Tumor Metabolism and Perfusion in Head and Neck Squamous Cell Carcinoma: Pretreatment<br />

Multimodality Imaging with 1H-MRS, DCE MRI and 18F-FDG PET: An Exploratory Study<br />

Jacobus FA Jansen 1 , Heiko Schoder 1 , Nancy Lee 1 , Hilda Stambuk 1 , Ya Wang 1 , Matthew Fury 1 , Snehal<br />

Patel 1 , David Pfister 1 , Jatin Shah 1 , Jason Koutcher 1 , Amita Shukla-Dave 1<br />

1 MSKCC, NY, United States<br />

The study aims to correlate pretreatment multimodality (MM) imaging data obtained with 1H-MRS, DCE-MRI and 18F-FDG PET in patients with head and<br />

neck squamous cell carcinoma (HNSCC) with neck nodal metastases for more precise assessment of the tumor metabolism and perfusion. Additionally,<br />

pretreatment MM imaging data was evaluated for its efficacy in prediction of short term response to treatment. In 29 HNSCC patients, Cho/W, Ktrans, ve,<br />

kep, 18F-FDG SUV measures were correlated. It was found that pretreatment MM imaging is valuable for the precise assessment of tumor biology, and<br />

maybe a predictive marker for short term response.<br />

DTI Brain & Spine - Clinical Applications<br />

Hall B Thursday 13:30-15:30<br />

2421. MR Visualization of Ventral Thalamic Nuclei<br />

Kei Yamada 1 , Kentaro Akazawa, Sachiko Yuen, Mariko Goto, Shigenori Matsushima, Akiko Takahata,<br />

Tsunehiko Nishimura<br />

1 Radiology, Kyoto Prefectural University of Medicine, Kyoto, Japan<br />

Ventrointermediate nucleus of the thalamus is located adjacent to and medial to the pyramidal tract and it can be identified on anisotropy maps of diffusion<br />

tensor imaging as well as inversion recovery sequences.<br />

2422. Distance Between Meyer's Loop Anterior Tip and Temporal Pole in Southern Chinese Measured with<br />

Diffusion Tensor Tractography Using BrainLAB and Philips FiberTrak Software<br />

Yi Xiang Wang 1 , X L. Zhu 2 , M Deng 1 , Y W. Siu 1 , C S. Leung 3 , Q Chan 4 , T M. Chan 2 , W S. Poon 2<br />

1 Department of Diagnostic Radiology and Organ Imaging, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin,<br />

NT, Hong Kong; 2 Division of Neurosurgery, Department of Surgery, The Chinese University of Hong Kong, Prince of Wales<br />

Hospital; 3 Jockey Club Centre for Osteoporosis Care and Control, The Chinese University of Hong Kong, Prince of Wales Hospital;<br />

4 Philips Healthcare, Hong Kong SAR, China<br />

Using Diffusion tensor tractography, the relationship of Meyer¡¯s loop to temporal lobe was investigated in 16 Southern Chinese subjects. Operator A is a<br />

neurosurgeon and BrainLAB software (Feldkirchen, Germany) was used. Operator B is a radiologist and Philips FiberTrak Software (Best, The Netherlands)<br />

was used. The results demonstrated a neurosurgeon and a radiologist using different DTT tools reached similar results on Meyer¡¯s loop to temporal pole<br />

(ML¨CTP) distance, suggesting BrainLAB and Philips FiberTrack software are able to provide comparable results. ML¨CTP distance from southern Chinese<br />

population was similar to literature data of Caucasian and Japanese population.

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