TRADITIONAL POSTER - ismrm

Poster Sessions
2022. Prenatal MR Imaging of Focal Cortical Gyration Anomalies at Early Stage of Development
Andrea Righini 1 , Cecilia Parazzini 1 , Chiara Doneda 1 , Laura Avagliano 2 , Filippo Arrigoni 1 , Mariangela
Rustico 1 , Gaetano Bulfamante 2 , Fabio Triulzi 1
1 Radiology and Neuroradiology, Children's Hospital V. Buzzi, Milan, Italy, Italy; 2 Pathology, San Paolo Hospital, Milan, Italy, Italy
We report the MRI patterns of focal cortical gyration anomalies, as they appear at a very early stage of the sulcation process (when fetal brain is almost
“lyssencephalic”). 22 cases (gestational age between 21 and 24 weeks) showed focal gyration anomalies, which could be divided in four basic patterns of
cortical rim distortion: “wart-like”, “saw-tooth”, major aberrant invaginating sulucs/i, single or multiple bumps. Most of these cases presented similarities to
the rat model of experimentally induced polymicrogyria. The present cohort shows how focal cortical gyration anomalies can be detected even at very early
sulcation process stage
2023. Fetal Imaging with Multitransmit MR at 3.0T: Preliminary Findings
Christopher G. Filippi 1 , Alisa Johnson 2 , Joshua P. Nickerson 3 , Betsy Sussman 4 , Jay Gonyea 5 , Trevor
Andrews 6
1 Radiology, University of Vermont School of Medicine-Fletcher Allen Health Care, Burlington, VT, United States; 2 radiology,
fletcher allen health care, burlington, VT, United States; 3 Radiology, Fletcher Allen Health Care, Burlington, VT, United States;
4 Radiology, Fletcher Allen Health Care-University of Vermont School of Medicine, Burlington, VT, United States; 5 Radiology,
University of Vermont School of Medicine, Burlington, VT, United States; 6 Radiology, Philips Health Care, Cleveland, OH, United
States
Multitransmit MR corrects B1 inhomogeneity which lessens dielectric shading, and a more uniform flip angle reduces focal SAR hot spots and allows for
safe fetal MR imaging at 3.0 T for brain anomalies, and using multitransmit MR with SENSE allows for faster scan times and better signal to noise. We
present 3 cases comparing 3.0T fetal MR imaging with and without multitransmit to follow-up MR imaging in the perinatal period to assess the accuracy,
image quality, and clinical feasibility of multitransmit MR imaging of the fetus at 3.0T
2024. Fetal Cortex Extraction Using Subject Specific Priors
Paul Aljabar 1 , Mellisa S. Damodaram 2 , Mary A. Rutherford 3 , Daniel Rueckert 1 , Joseph V. Hajnal 3
1 Visual Information Processing group, Department of Computing, Imperial College London, London, United Kingdom; 2 Division
of Surgery, Oncology, Reproductive Biology and Anaesthetics, Imperial College London, London, United Kingdom; 3 Robert Steiner
MR Unit, Imaging Sciences Department, MRC Clinical Sciences Centre, Hammersmith Hospital, Imperial College London, London,
United Kingdom
Automatic segmentation of the cortex from fetal brain MRI has potential as a significant tool in developmental neuroscience. We developed an accurate and
robust method for extracting the cortex based on creating subject specific cortical priors using label propagation from automatically produced neonatal
atlases. The method was tested on 12 fetal subjects with gestational age range from 20 -30 weeks, imaged using single shot Fast Spin Echo sequences with
Slice to Volume (SVR) 3D reconstruction. The method was validated against manual segmentation and found to yield a mean error of 1.15±1.03mm.
2025. White Matter Maturation of Normal Human Fetal Brain-An in Vivo Diffusion Tensor Imaging
Tractography Study
Emilie ZANIN 1 , Jean-Philippe Ranjeva 1 , Sylviane Confort-Gouny 1 , Maxime Guye 1 , Danielle Denis 2 ,
Patrick J. Cozzone 1 , Nadine GIRARD 1
1 CRMBM UMR CNRS 6612, Marseille, France; 2 CHU Nord, Marseille, France
Objective of this study was to demonstrate the ability of DTI tractography, to assess in vivo and in utero a crucial stage of human fetal brain development:
the white matter maturation. We observed that evolution of diffusion characteristics during gestation were different for cortical spinal tract, optic radiations,
anterior, middle and posterior part of corpus callosum reflecting the presence of structural heterogeneity between these large WM tracts during gestation.
Non-linear curve fittings of normalized longitudinal and radial water diffusivities as a function of age identify 3 different phases of maturation with specific
dynamics for each WM bundle type.
2026. Birth the Hardest Journey in Life and a Brain Warping Experience. a Deformation Field Morphology
Study of Fetal Brain During Labor
Peter Kochunov 1 , Carlos Castro 2 , Gerald Schatten 3 , David Purdy 4 , Duff Davis 1
1 Reseach Imaging Institute, UTHSCSA, san antonio, TX, United States; 2 Ob / Gyn and Reproductive Sciences, University of
Pittsburgh School of Medicine, Pittsburgh, PA, United States; 3 Pittsburgh Development Center, University of Pittsburgh School of
Medicine, Pittsburgh, PA, United States; 4 Siemens Medical Solutions, Malvern, PA , United States
Neonates of Old World monkeys have the longest gestational development phase among comparably sized mammals, and as a consequence, neonatal heads
approach the size of the birthing canal. This can lead to cephalo-pelvic limitation, a situation in which the size of the birthing canal presents a physical limit
on the size and shape of neonate during parturition. An unexpected labor provided a rare opportunity to map deformations experienced by the neonatal brain
during these normal contractions. A deformation field analysis produced a 3-D array of 3-D displacement vectors, showing dramatic regional deformation of
the fetal brain during normal labor.