TRADITIONAL POSTER - ismrm

Poster Sessions
1177. Acute Vs. Tonic Muscular Pain: Changes in Cerebral Blood Flow as Imaged by Arterial Spin Labeling
Daron Gordon Owen 1,2 , Collin Franklin Clarke 3 , Sugantha Ganapathy 3 , Frank S. Prato 1,4 , Keith S. St.
Lawrence 1,2
1 Imaging Program, Lawson Health Research Institute, London, Ontario, Canada; 2 Medical Biophysics, The University of Western
Ontario, London, Ontario, Canada; 3 Anesthesia and Perioperative Medicine, The University of Western Ontario, London, Ontario,
Canada; 4 Imaging, St. Joseph's Hospital, London, Ontario, Canada
The cerebral representation of acute pain is well established, whereas that of tonic pain is not due to difficulties in applying functional imaging to prolonged
stimuli. We used arterial spin labeling (ASL) to investigate the neural activation associated with tonic muscular pain. The use of ASL allows direct
comparison between studies. Compared to our previous study incorporating both acute and tonic phases, we observed smaller CBF changes, and only in
bilateral insula and frontal gyrus, despite similar pain levels. A likely explanation is that the acute phase of the previous study induced anxiety and distress,
whereas our tonic pain stimulus did not.
1178. Age and Gender Effects on Whole Brain Cerebral Blood Flow in Adolescents
Ai-Ling Lin 1 , Timothy Q. Duong 1 , Peter T. Fox 1 , Douglas E. Williamson 2
1 Research Imaging Institute, University of Texas Health Science Center at San Antonio, San Antonio, TX, United States; 2 Psychiatry,
University of Texas Health Science Center at San Antonio, San Antonio, TX, United States
Both gender and have long been assumed to have effects on brain function and cerebral blood flow (CBF). However, the effects of gender and age on CBF
have not well explored in adolescents. To increase our knowledge in this area, MRI techniques were employed to measure global CBF with 267 adolescents.
Our result shows that significant difference in CBF was observed between 12 and 15 years of age. However, no significant main effects of gender were
found in the study. The results provide better understanding of brain functions for adolescent across age and gender.
1179. A FMRI Study of Temporary Hearing Threshold Shift
Piotr Bogorodzki 1 , Tomasz Wolak 2 , Krzysztof Kochanek 2 , Ewa Piatkowska-Janko 1 , Piotr Skarzynski 2 , Adam
Pilka 2 , Jozef Kotus 3 , Andrzej Czyzewski 3
1 Institute of Radioelectronics, Warsaw University of Technology, Warsaw, Poland; 2 Institute of Physiology and Pathology of Hearing;
3 Gdansk University of Technology, Gdansk, Poland
Several empirical studies have shown, that long lasting acoustic noise exposure causes on humans effect called Temporary Hearing Threshold Shift (TTS).
This work presents results from 15 healthy subjects participating in a fMRI study of TTS consisting of two runs: ⣣pre⣣ with silent GE EPI scanning and
⣣post⣣ identical to ⣣⣣pre⣣, but after 15min high volume noise exposure (causing a mean 12 dB TTS effect). Group level analysis showed
activations in auditory cortex (T=13.3 in lh, and 10.45 in rh). A two-sample T-test fails for post>pre contrast, however detailed ROI analysis shows
differences in sub-auditory areas.
1180. Functional Imaging of Observation of Action in Elite Archers Using Video of Western-Style Archery
Task
Hui-jin Song 1 , Joo-hyun Kim 1 , Jeehye Seo 1 , Moon-jung Hwang 2 , Young-ju Lee 2 , Kyung Jin Suh 3 , Sung Woo
Kim 3 , Young Hwan Lee 4 , Dong Soo Yoo 5 , Yongmin Chang 1,6
1 Medical & Biological Engineering, Kyungpook National University, Daegu, Korea, Republic of; 2 GE healthcare, Seoul; 3 Dongguk
University, Gyungju; 4 Radiology, College of Medicine, Catholic University, Daegu; 5 Radiology, College of Medicine, Dankook
University, Chunan; 6 Diagnostic Radiology, Kyungpook National University, Daegu, Korea, Republic of
Although the mirror neuron system has been extensively studied, no functional imaging data are currently available to gain insight in the possible difference
of the mirror system between experts and novices. Therefore, the aim of the present study is to investigate the differences of activation in the mirror neuron
system during viewing tool use familiar to experts between expert archers and novice subjects. Our results demonstrated that expert archers showed strong
activation in the mirror neuron system during viewing videos of Western-style archery relative to inexpert control subjects. Taken together, our data
consistent with previous reports suggest that human mirror neuron system could contain representations of tool use and expand motor repertoire with tool
use experiences.
1181. Localization of the Hand Motor Area Using BOLD and ASL FMRI
Marco Pimentel 1 , Pedro Vilela 2 , Inês Sousa 3,4 , Patricia Figueiredo 3
1 Faculdade de Ciências e Tecnologia, Universidade Nova de Lisboa, Lisbon, Portugal; 2 Imaging Department, Hospital da Luz, Lisbon,
Portugal; 3 Instituto Superior Técnico, Lisbon, Portugal; 4 Healthcare Sector, Siemens, S.A., Portugal
Previous studies have shown that ASL-based fMRI exhibits better spatial specificity than the most commonly used BOLD contrast. Here, we compared the
localization of the hand motor area obtained by simultaneous ASL-BOLD fMRI and standard BOLD fMRI at 3T with well established anatomical
landmarks, in a group of 15 healthy subjects. Our results indicate that the localization of the hand motor area obtained using ASL fMRI is significantly less
variable and closer to the hand motor cortex anatomical landmarks than the one produced by BOLD fMRI. This supports the notion that ASL may more
accurately localize brain activation than BOLD.
1182. Understanding Consciousness from Information and Integration Within the Thalamocortical System
Xiaolin Liu 1 , Jingsheng Zhou 2 , Anthony G. Hudetz 3 , Shi-Jiang Li 1
1 Biophysics, Medical College of Wisconsin, Milwaukee, WI, United States; 2 Rehabilitation Department, Xuanwu Hospital Capital
Medical University, Beijing, China; 3 Anesthesiology, Medical College of Wisconsin, Milwaukee, WI, United States
Understanding the neural mechanisms of consciousness requires identification of the nature of contributions from each of the potential neural correlates,
which together generate a complete cognitive experience. We examined the specific and nonspecific thalamic connections in the brain based on the
neuroanatomical findings implicating their respective functional roles in sustaining information and integration, which are essential to consciousness. Our
results endorse the view that the thalamocortical system is essential to consciousness, and support the hypothesis that the nonspecific thalamic connections
largely reflect brain regions that are responsible for information integration, potentially sustaining various awareness functions.