TRADITIONAL POSTER - ismrm

Poster Sessions
2467. Bone Marrow Perfusion Magnetic Resonance Imaging in Patients with Osteoporotic Vertebral
Compression Fractures: Peak Enhancement Ratio Is an Independent Predictor for Intraosseous Vacuum
Phenomena
Wei-Che Lin 1,2 , Hsiu-Ling Chen 1 , Yu-Fan Cheng 1 , Chun-Chung Lui 1
1 Department of Diagnostic Radiology, Chang Gung Memorial Hospital - Kaohsiung Medical Center, Chang Gung University College
of Medicine, Kaohsiung, Taiwan, Taiwan; 2 Department of Biomedical Imaging and Radiological Sciences, National Yang-Ming
University, Taipei, Taiwan, Taiwan
Decrease bone marrow perfusion as reflected by lower peak enhancement ratio (PER) value in dynamic contrast-enhanced MRI (DCE-MRI) can
independently predict the presence of intraosseous cleft in patients with osteoporotic vertebral compression fractures.DCE-MRI can help distinguish the
more frail patients after VCF suitable for more tailored anti-osteoporotic therapy and can also identify delicate osteoporotic patients for advance treatment
before an injury can occur.
2468. Quantitative Assessment of the Cervical Spinal Cord Damage in Neuromyelitis Optica Using Diffusion
Tensor Imaging at 3T
Wenshu Qian 1 , Henry Mak 1 , Queenie Chan 2 , Koon Ho Chan 3 , Mina Kim 1
1 Diagnostic Radiology, The University of Hong Kong, Hong Kong, China; 2 Philips Healthcare, Hong Kong, China; 3 Medicine, The
University of Hong Kong, Hong Kong, China
Neuromyelitis optica (NMO) is an inflammatory and demyelinating disease which consists of optic neuritis and myelitis. Since it usually involves acute and
severe attacks, early diagnosis is of vital importance for proper treatment. However, current diagnostic imaging techniques are not sensitive to degenerative
changes in early stage of NMO. In this study, we aimed to investigate the normal appearing cervical spinal cord damage in patients with NMO using
diffusion tensor imaging (DTI). Our results show DTI-derived metrics can sensitively assess the microstructural abnormalities, suggesting DTI may have
great potential as a useful diagnostic tool in detecting early stage of NMO.
Breast MR
Hall B Tuesday 13:30-15:30
2469. High Resolution MR Imaging and Spectroscopy of the Human Breast at 7T Using a Focused Field RF
Coil Setup
Dennis WJ Klomp 1 , Alexander Raaijmakers 2 , Mies Korteweg 1 , Bart van de Bank 1 , Cecilia Possanzini 3 ,
Vincent Boer 1 , Fredy Visser 3 , Nico van de Berg 2 , Peter Luijten 1
1 Radiology, University Medical Center Utrecht, Utrecht, Netherlands; 2 Radiotherapy, University Medical Center Utrecht, Utrecht,
Netherlands; 3 Philips Health Care
MRI of the human breast at higher B0 fields, like 7T, can improve SNR, but may be restricted by non uniform excitation and restricted RF power deposition
(SAR). Here we propose the use of a RF coil setup with focused field in the female breast to gain from the maximum sensitivity that can be obtained at 7T,
illustrated by high resolution MRI and MRS in healthy subjects and patients.
2470. Simple Approach for Increasing SNR, Reducing Breast Shading and Improving Fat Suppression at 3T
Ileana Hancu 1 , Laura Sacolick 2 , Seung-Kyun Lee 1 , W Thomas Dixon 1 , Randy Giaquinto 1 , Graeme
McKinnon 3 , Vijayanand Alagappan 4
1 GE Global Research Center, Niskayuna, NY, United States; 2 GE Global Research Center, Munich, Germany; 3 GE Healthcare,
Waukesha, WI, United States; 4 GE Healthcare, Aurora, OH, United States
The main cause of the shading and improper fat suppression artifacts in breast imaging at 3T was identified as a bimodal distribution of the excitation field.
A correction approach, based on the permanent placement of a passive loop tuned to 150MHz over the (always weaker) right side of a standard 8 channel
breast receive array, was shown to mitigate the problem, result in more uniform B1transmit, better fat suppression and higher SNR, all with lower specific
absorption rate.
2471. Differentiation Between Intermingled and Central Type Breast Parenchymal Patterns Using
Quantitative Morphological Parameters Based on Segmented Dense Tissue
Ke Nie 1 , Jeon-Hor Chen 1,2 , Daniel Chang 1 , Chieh-Chih Hsu 2 , Orhan Nalcioglu 1 , Min-Ying Lydia Su 1
1 Tu & Yuen Center for Functional Onco-Imaging, University of California, Irvine, Irvine, CA, United States; 2 Department of
Radiology, China Medical University, Taichung, Taiwan
Breast parenchymal pattern is a well-known risk factor. The commonly used term ¡®breast density¡¯ only measures the amount of breast tissue, not the
relative distribution between the fat and fibroglandular tissue. In this study, we developed quantitative parameters to characterize different parenchymal
distribution patterns (intermingled vs. central types) based on the segmented dense tissue on 3D MRI. In a dataset of 230 cases, the area under the ROC
curve could reach to 0.94 using combined parameters. These features can be further used to investigate the relationship between parenchymal pattern and the
cancer risk.