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Main trends of research in the social and human ... - unesdoc - Unesco

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362 Jean Bourgeois-Pichat<br />

<strong>in</strong>to account <strong>the</strong> age at which contraceptive methods beg<strong>in</strong> to be used, <strong>and</strong><br />

we shall dist<strong>in</strong>guish between sexual <strong>in</strong>tercourse that is sanctioned as opposed<br />

to sexual <strong>in</strong>tercourse that is not. We shall also have to bear <strong>in</strong> m<strong>in</strong>d <strong>the</strong> various<br />

contraception techniques, as well as <strong>the</strong> various ways <strong>of</strong> effect<strong>in</strong>g sexual<br />

<strong>in</strong>tercourse. No doubt <strong>the</strong> latter have a certa<strong>in</strong> bear<strong>in</strong>g on <strong>the</strong> efficacy <strong>of</strong> con-<br />

traception.<br />

Endogenous <strong>and</strong> exogenous mortality<br />

29. Let us return to that child born alive, usually well proportioned though<br />

occasionally deformed, whom we left just now at <strong>the</strong> very moment he was<br />

start<strong>in</strong>g life <strong>in</strong> this world. At <strong>the</strong> <strong>in</strong>stant when <strong>the</strong> fertilized ovule beg<strong>in</strong>s its<br />

new existence, an age<strong>in</strong>g process is set <strong>in</strong> motion. Dur<strong>in</strong>g a certa<strong>in</strong> time <strong>the</strong> for-<br />

ces <strong>of</strong> growth <strong>and</strong> <strong>of</strong> decay are go<strong>in</strong>g to co-exist <strong>in</strong> <strong>the</strong> same <strong>in</strong>dividual, <strong>the</strong>n<br />

gradually <strong>the</strong> latter will ga<strong>in</strong> <strong>the</strong> upper h<strong>and</strong> <strong>and</strong> lead him on f<strong>in</strong>ally to his<br />

death. But before this f<strong>in</strong>al event takes place, <strong>the</strong> <strong>in</strong>dividual will have to go<br />

through a series <strong>of</strong> crises characterized by a variety <strong>of</strong> biological disorders<br />

putt<strong>in</strong>g his existence <strong>in</strong> danger which he will have to overcome.<br />

That, grosso modo, is <strong>the</strong> sequence <strong>of</strong> biological phenomena that will accom-<br />

pany him from <strong>the</strong> cradle to <strong>the</strong> grave.<br />

30. The causes <strong>of</strong> biological disorders lead<strong>in</strong>g to illness can be classified under<br />

two ma<strong>in</strong> head<strong>in</strong>gs : ei<strong>the</strong>r <strong>the</strong> <strong>in</strong>dividual carries <strong>the</strong> cause <strong>in</strong> question with<strong>in</strong><br />

him, or else it is brought to him by <strong>the</strong> external environment. However, this<br />

dist<strong>in</strong>ction between endogenous <strong>and</strong> exogenous causes <strong>of</strong> disease is a little too<br />

arbitrary. A disease is always <strong>the</strong> result <strong>of</strong> a variety <strong>of</strong> causes <strong>in</strong> which endoge-<br />

nous <strong>and</strong> exogenous are mixed toge<strong>the</strong>r. It seems that <strong>in</strong>dividuals have certa<strong>in</strong><br />

predispositions for contract<strong>in</strong>g a particular disease. In <strong>the</strong> case <strong>of</strong> cancer <strong>of</strong> <strong>the</strong><br />

lung, for <strong>in</strong>stance, it is possible to dist<strong>in</strong>guish between three separate classes <strong>of</strong><br />

persons: those who are predisposed to this disease <strong>and</strong> will contract it even if<br />

<strong>the</strong>y do not smoke; those who are pro<strong>of</strong> aga<strong>in</strong>st it <strong>and</strong> will not be affected even<br />

if <strong>the</strong>y do smoke; <strong>and</strong> those who contract <strong>the</strong> disease through smok<strong>in</strong>g but who<br />

can avoid it by not smok<strong>in</strong>g, or, at any rate, by smok<strong>in</strong>g less. Similarly, it is<br />

<strong>of</strong>ten hard to dist<strong>in</strong>guish between a deformity due to some alteration <strong>in</strong> <strong>the</strong><br />

chromosomes which occurred at <strong>the</strong> time <strong>of</strong> conception <strong>and</strong> one acquired<br />

dur<strong>in</strong>g life <strong>in</strong> <strong>the</strong> uterus, due, for <strong>in</strong>stance, to some disease <strong>of</strong> <strong>the</strong> mo<strong>the</strong>r. As we<br />

come to underst<strong>and</strong> all <strong>the</strong>se mechanisms better, demography will have to<br />

consider <strong>the</strong> re-classify<strong>in</strong>g <strong>of</strong> deleterious factors, <strong>and</strong> it will no doubt be led to<br />

adopt a more subtle dist<strong>in</strong>ction than <strong>the</strong> one which consists <strong>in</strong> acknowledg<strong>in</strong>g<br />

only <strong>the</strong> two sets <strong>of</strong> causes - endogenous <strong>and</strong> exogenous.<br />

3 I. In an endogenous disease, <strong>the</strong> deleterious factor can be present at birth <strong>in</strong> <strong>the</strong><br />

form, for example, <strong>of</strong> a chromosomal alteration, but it can also be acquired <strong>in</strong><br />

<strong>the</strong> course <strong>of</strong> existence, as a result <strong>of</strong> <strong>the</strong> actual function<strong>in</strong>g <strong>of</strong> <strong>the</strong> life-giv<strong>in</strong>g<br />

mechanisms. These two possibilities are largely related to two sets <strong>of</strong> causes <strong>of</strong><br />

disease: deformities <strong>and</strong> senescence.<br />

In <strong>the</strong> case <strong>of</strong> an exogenous disease, <strong>the</strong> ailment spr<strong>in</strong>gs from an encounter

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