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Main trends of research in the social and human ... - unesdoc - Unesco

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396 Jean Bourgeois-Pichat<br />

sons concerned dur<strong>in</strong>g <strong>the</strong>ir educational careers. It <strong>the</strong>refore goes far beyond a<br />

mere study <strong>of</strong> mortality <strong>in</strong>cidence; on <strong>the</strong> o<strong>the</strong>r h<strong>and</strong>, it is conf<strong>in</strong>ed to a partic-<br />

ular group <strong>of</strong> <strong>social</strong> classes <strong>and</strong> covers only a short phase <strong>of</strong> a lifetime.<br />

135. In addition, <strong>the</strong>re are <strong>the</strong> studies conducted <strong>in</strong> <strong>the</strong> United States by <strong>the</strong><br />

Metropolitan Life Insurance Company on its clientkle. Although not represen-<br />

tative <strong>of</strong> <strong>the</strong> American population as a whole, this clientkle, consist<strong>in</strong>g <strong>of</strong> several<br />

tens <strong>of</strong> millions <strong>of</strong> persons, enables <strong>the</strong> company to study <strong>the</strong> <strong>in</strong>fluence on <strong>the</strong><br />

death-rate <strong>of</strong> factors connected with <strong>the</strong> way <strong>of</strong> liv<strong>in</strong>g. Research is also carried<br />

out on morbidity.<br />

136. Rapid progress is be<strong>in</strong>g made, too, <strong>in</strong> <strong>research</strong> on mortality <strong>of</strong> genetic<br />

orig<strong>in</strong>. There are frequent discoveries <strong>of</strong> chromosomal disorders responsible<br />

for various physiological ailments. It has been demonstrated that <strong>the</strong> frequency<br />

<strong>of</strong> chromosomal disorders <strong>in</strong> new-born children is 4 per 1,000, <strong>and</strong> that chromosomal<br />

anomalies account for 20 % <strong>of</strong> <strong>the</strong> root cause <strong>of</strong> miscarriages.<br />

137. The question <strong>of</strong> parental <strong>in</strong>compatibilities between blood groups raises a<br />

number <strong>of</strong> problems at <strong>the</strong> present time from <strong>the</strong> po<strong>in</strong>t <strong>of</strong> view <strong>of</strong> selection. We<br />

are well acqua<strong>in</strong>ted with <strong>the</strong> problem <strong>of</strong> Rh <strong>in</strong>compatibilities (hemolytic disease<br />

<strong>in</strong> new-born children), but it is thought that <strong>the</strong>y are to be found also <strong>in</strong> <strong>the</strong><br />

ABO <strong>and</strong> m systems, among o<strong>the</strong>rs, with very different mechanisms: gametic<br />

selection, selection <strong>in</strong> utero, mort<strong>in</strong>atality, post-natal selection, specific mortali-<br />

ty. All <strong>the</strong>se aspects are <strong>of</strong> great importance from <strong>the</strong> po<strong>in</strong>t <strong>of</strong> view <strong>of</strong> public<br />

health.<br />

Procreation <strong>in</strong> <strong>the</strong> <strong>human</strong> race<br />

138. Works on <strong>the</strong> subject <strong>of</strong> procreation <strong>in</strong> <strong>the</strong> <strong>human</strong> race relate to ano<strong>the</strong>r<br />

equally important field <strong>of</strong> <strong>research</strong>. Three ma<strong>in</strong> sectors may be dist<strong>in</strong>guished:<br />

First, <strong>the</strong> study <strong>of</strong> <strong>the</strong> biological <strong>and</strong> physiological aspects <strong>of</strong> <strong>human</strong> repro-<br />

duction. Here aga<strong>in</strong>, we f<strong>in</strong>d a vast programme <strong>of</strong> <strong>research</strong> launched by WHO.<br />

A service specialized <strong>in</strong> <strong>the</strong> reproduction <strong>of</strong> <strong>the</strong> <strong>human</strong> species was established<br />

<strong>in</strong> 1965 at <strong>the</strong> Organization’s headquarters <strong>in</strong> Geneva. It has carried out <strong>the</strong><br />

follow<strong>in</strong>g work:<br />

a. It has organized a number <strong>of</strong> meet<strong>in</strong>gs <strong>of</strong> experts with <strong>the</strong> object <strong>of</strong><br />

review<strong>in</strong>g <strong>the</strong> present state <strong>of</strong> our knowledge <strong>and</strong> <strong>in</strong>dicat<strong>in</strong>g new l<strong>in</strong>es <strong>of</strong> re-<br />

search. The conclusions <strong>of</strong> <strong>the</strong>se discussions have been published <strong>in</strong> <strong>the</strong> series <strong>of</strong><br />

technical reports issued by WHO. The mere mention <strong>of</strong> <strong>the</strong>ir titles is enough to<br />

show how <strong>the</strong>y fit <strong>in</strong>to <strong>the</strong> general scheme <strong>of</strong> this chapter: biology <strong>of</strong> reproduc-<br />

tion (1963),34 physiology <strong>of</strong> breast-feed<strong>in</strong>g (1963), effects <strong>of</strong> conf<strong>in</strong>ement on <strong>the</strong><br />

foetus <strong>and</strong> new-born child (1964), neuro-endocr<strong>in</strong>ology <strong>and</strong> <strong>the</strong> reproduction<br />

<strong>of</strong> <strong>the</strong> <strong>human</strong> species (1964), mechanisms <strong>of</strong> action <strong>of</strong> sexual hormones <strong>and</strong><br />

allied substances (1964), biochemistry <strong>and</strong> microbiology <strong>of</strong> <strong>the</strong> genital organs<br />

<strong>of</strong> man <strong>and</strong> woman (1969, immunization <strong>of</strong> <strong>human</strong> reproduction (1969,<br />

chemistry <strong>and</strong> physiology <strong>of</strong> oral contraceptives <strong>and</strong> <strong>the</strong>ir cl<strong>in</strong>ical aspects<br />

(1969, gametes (1969, <strong>the</strong> sterilet <strong>and</strong> its cl<strong>in</strong>ical aspects (1966).

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