Labelling Review row-Online

Bond
Bond Epitope Retrieval Solution 1
1 L AR9961 P
For In Vitro Diagnostic Use
Components
Bond Epitope Retrieval Solution 1 is a 1 L ready-to-use, citrate based pH 6.0
solution. It is specifically for heat-induced epitope retrieval (HIER) on the
automated Bond system.
Application
Bond Epitope Retrieval Solution 1 is for use on formalin-fixed, paraffinembedded
tissue sections to expose epitopes within tissue that have been
masked during fixation. The solution is gentle on sections as it has a reduced
boiling temperature and utilizes Bond's Covertile technology to prevent
reagent evaporation. Some antibodies, such as Bond ready-to-use Thyroid
Transcription Factor-1, stain optimally when used with Bond Epitope
Retrieval Solution 1. Testing should be carried out to optimize per-formance.
Human lung stained for TTF-1 with Bond ready-to-use Thyroid Transcription Factor-1 (SPT24,
PA0364), using Bond Polymer Refine Detection and Bond Epitope Retrieval Solution 1.
Bond Epitope Retrieval Solution 2
1 L AR9640 P
For In Vitro Diagnostic Use
Components
Bond Epitope Retrieval Solution 2 is a 1 L ready-to-use, EDTA based pH 9.0
solution. It is specifically for heat-induced epitope retrieval (HIER) on the
Bond system.
Application
Bond Epitope Retrieval Solution 2 is for use on formalin-fixed, paraffinembedded
tissue sections to expose epitopes within tissue that have been
masked during fixation. The solution is gentle on sections as it has a
reduced boiling temperature and utilizes Bond's Covertile technology to
prevent reagent evaporation. Some antibodies, such as Bond ready-to-use
CD3 (LN10), stain optimally when used with Bond Epitope Retrieval
Solution 2. Testing should be carried out to optimize performance.
Human tonsil stained for CD3 with Bond ready-to-use CD3 (LN10, PA0533), using Bond Polymer
Refine Detection and Bond Epitope Retrieval Solution 2.
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Alpha Fetoprotein
Clone C3
7 mL Bond ready-to-use PA0963 P
For In Vitro Diagnostic Use
Alpha Fetoprotein (AFP) is an oncofetal antigen of 70 kD found in body fluids,
which if detected in high concentrations has clinical implications. AFP is
expressed in fetal liver but is not present under normal circumstances in
healthy adult tissues. It is reported to be expressed in a proportion of germ
cell tumors, with high frequency in yolk sac tumors.
Also available as a Novocastra concentrate, refer to page 56.
Yolk sac tumor: immunohistochemical staining with Bond ready-to-use Alpha Fetoprotein (C3)
using Bond Polymer Refine Detection.
Anaplastic Lymphoma Kinase
Clone 5A4
7 mL Bond ready-to-use PA0306 P (HIER)
For In Vitro Diagnostic Use
Anaplastic Large Cell Lymphoma (ALCL) is usually composed of large
pleomorphic cells which, are reported to express CD30 antigen and the
epithelial membrane antigen (EMA). These tumor cells tend to occur in
younger individuals and may be associated with cutaneous and extranodal
involvement. A proportion of these cases contain a chromosomal
translocation t(2;5) (p23;q35). This results in a hybrid gene encoding part of
the nucleophosmin (NPM) gene joined to the cytoplasmic domain of the
anaplastic lymphoma kinase (ALK) gene, giving rise to the protein, p80.
Large cell lymphomas account for approximately 25 percent of all non-
Hodgkin's lymphomas in children and young adults, of which one third
carries the NPM-ALK gene translocation.
Also available as a Novocastra concentrate, refer to page 54.
Anaplastic lymphoma: immunohistochemical staining with Bond ready-to-use Anaplastic
Lymphoma Kinase (5A4) using Bond Polymer Refine Detection.
Products in this catalog are subject to regulatory approval.
This catalog is not for use in the USA.