Labelling Review row-Online

Human Chorionic
Gonadotrophic Hormone
Polyclonal
7 mL Bond ready-to-use PA0014 P (HIER)
For In Vitro Diagnostic Use
Human chorionic gonadotrophin (hCG) is a glycoprotein hormone
produced by trophoblastic cells of the placenta beginning 10 to 12 days
after conception. Maintenance of the fetus in the first trimester of
pregnancy requires the production of hCG, which binds to the corpus
luteum of the ovary which is stimulated to produce progesterone which
in turn maintains the secretory endometrium. hCG is composed of two
subunits, alpha and beta. The alpha subunit of hCG is identical to the
subunit of luteinising hormone, thyroid stimulating hormone and follicle
stimulating hormone. The common alpha chain and the hormonespecific
beta chains have molecular weights of 14 kD and 17 kD,
respectively. The hCG beta-subunit is unique in the family of betacontaining
glycoprotein hormones in that it contains an extension of 29
amino acids at its COOH end. It is believed that the C-terminal region of
the HCG-beta subunit plays a role in the intracellular behavior of the
heterodimer.
Also available as a Novocastra concentrate, refer to page 121.
Placenta: immunohistochemical staining with Bond ready-to-use Human Chorionic
Gonadotrophic Hormone (Polyclonal) using Bond Polymer Refine Detection.
Human Follicle Stimulating Hormone
Clone INN-hFSH-60
7 mL Bond ready-to-use PA0693 P (Enzyme)
For In Vitro Diagnostic Use
Follicle stimulating hormone (FSH) is a pituitary hormone of 35 kD which is
involved in the maturation of ovarian follicles and estrogen secretion in
females. In males, FSH stimulates the secretion of testosterone.
Product Specific Information
Human Follicle Stimulating Hormone (INN-hFSH-60) recognizes the beta 2
epitope of the beta subunit of human FSH.
Pituitary: immunohistochemical staining with Bond ready-to-use Human Follicle Stimulating
Hormone (INN-hFSH-60) using Bond Polymer Refine Detection.
Human Growth Hormone
Polyclonal
7 mL Bond ready-to-use PA0704 P
For In Vitro Diagnostic Use
Growth hormone (GH), somatotropin, is the primary hormone responsible for
regulating overall body growth and is also important in organic metabolism. It
is synthesized by acidophilic or somatotropic cells of the anterior pituitary
gland. Human GH has a molecular weight of 22 kD. GH stimulates growth
indirectly by promoting the liver's production of somatomedins, which act
directly on bone and soft tissue to cause growth. GH exerts direct metabolic
effects on the liver, adipose tissue and muscle. In general, growth hormone
enhances protein synthesis, conserves carbohydrates and uses up fat stores.
Also available as a Novocastra concentrate, refer to page 121.
Pituitary: immunohistochemical staining with Bond ready-to-use Human Growth Hormone
(Polyclonal) using Bond Polymer Refine Detection.
Inhibin (alpha)
Clone R1 New!
7 mL Bond ready-to-use PA0110 P (HIER)
For In Vitro Diagnostic Use
Inhibins are peptide hormones produced by the granulosa cells in female
follicles and by Sertoli cells in the male seminiferous tubules. They appear to
oppose the functions of activins, as inhibins and activins inhibit and activate,
respectively, the secretion of follitropin by the pituitary gland. Inhibin has 2
subunits (alpha and beta) that are coded by separate genes. The alpha
subunit determines whether inhibin or activin will be produced. The antibody
may be of value in the differentiation of adrenocortical tumors, placental and
gestational trophoblastic lesions and sex cord stromal tumors.
Granulosa theca cell tumor: immunohistochemical staining with Bond ready-to-use Inhibin (R1)
using Bond Polymer Refine Detection.
F Frozen I Immunofluorescence E Electron microscopy
P Paraffin C Flow cytometry O Other applications
W Western blotting
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