Labelling Review row-Online
Labelling Review row-Online
Labelling Review row-Online
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Bond<br />
Insulin<br />
Clone 2D11-H5<br />
7 mL Bond ready-to-use PA0620 P<br />
For In Vitro Diagnostic Use<br />
Insulin is a hormone secreted by the beta cells of the islets of Langerhans in<br />
the pancreas. It promotes glycogen storage, formation of triglycerides, and<br />
synthesis of protein and nucleic acids. Reports of immunocytochemical<br />
investigation reveal the presence of insulin in the cytoplasm of certain islet<br />
tumors. However, in some instances insulin-positive granules are sparse<br />
and form a margin against the cell membrane.<br />
Also available as a Novocastra concentrate, refer to page 125.<br />
Pancreas: immunohistochemical staining with Bond ready-to-use Insulin (2D11-H5) using Bond<br />
Polymer Refine Detection.<br />
Ki67<br />
Clone MM1<br />
7 mL Bond ready-to-use PA0118 P (HIER)<br />
Clone K2 New!<br />
7 mL Bond ready-to-use PA0230 P (HIER)<br />
For In Vitro Diagnostic Use<br />
The Ki67 antigen is a nuclear protein which is expressed in all active parts of<br />
the cell cycle (G1, S, G2 and mitosis) but is absent in resting cells (G0). In<br />
contrast to many other cell cycle-associated proteins, the Ki67 antigen is<br />
consistently absent in quiescent cells and is not detectable during DNA<br />
repair processes. Thus, the presence of Ki67 antigen is strictly associated<br />
with the cell cycle and confined to the nucleus, suggesting an important role<br />
in the maintenance and/or regulation of the cell division cycle.<br />
Product Specific Information<br />
Bond ready-to-use Ki67 is recommended for the assessment of cell<br />
proliferation in normal and neoplastic tissues.<br />
Also available as a Novocastra concentrate, refer to page 126.<br />
Breast invasive ductal carcinoma: immunohistochemical staining with Bond ready-to-use Ki67<br />
(K2) using Bond Polymer Refine Detection.<br />
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For detailed information on all products please visit our website:<br />
www.leica-microsystems.com<br />
Luteinizing Hormone<br />
Clone C93 New!<br />
7 mL Bond ready-to-use PA0655 P<br />
For In Vitro Diagnostic Use<br />
Luteinising hormone (LH) is a trophic hormone which modulates the<br />
secretory activity of other endocrine glands. It is produced by the anterior<br />
hypophysis of the pituitary gland. This glycoprotein hormone, like human<br />
follicle stimulating hormone and thyroid stimulating hormone, is composed<br />
of a common alpha-subunit and a specific beta-subunit which characterizes<br />
each of these hormones.<br />
Pituitary: immunohistochemical staining with Bond ready-to-use Luteinizing Hormone (C93)<br />
using Bond Polymer Refine Detection.<br />
Macrophage Marker<br />
Clone MAC387<br />
7 mL Bond ready-to-use PA0752 P (HIER)<br />
For In Vitro Diagnostic Use<br />
L1, a member of the S-100 family of proteins, is reported to be found on<br />
neutrophils, monocytes, certain reactive macrophages and squamous<br />
mucosal epithelia.<br />
Product Specific Information<br />
Clone MAC387 is reported to be specific for the leucocyte antigen L1.<br />
Lung: immunohistochemical staining with Bond ready-to-use Macrophage Marker (MAC387)<br />
using Bond Polymer Refine Detection.<br />
Products in this catalog are subject to regulatory approval.<br />
This catalog is not for use in the USA.
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