Labelling Review row-Online

CD8
Clone 4B11
7 mL Bond ready-to-use PA0183 P (HIER)
For In Vitro Diagnostic Use
The CD8 antigen is found on a sub-set of normal cytotoxic/supressor cells,
which make up 20-30 percent of peripheral blood lymphocytes. It has also
been reported on natural killer cells, 80 percent of thymocytes and subpopulations
of peripheral blood null cells and bone marrow cells.
T cell disorders can be characterized using a panel of antibodies that
include CD8 (4B11).
Also available as a Novocastra concentrate, refer to page 72.
Tonsil: immunohistochemical staining with Bond ready-to-use CD8 (4B11) using Bond Polymer
Refine Detection.
CD10
Clone 56C6
7 mL Bond ready-to-use PA0270 P (HIER)
For In Vitro Diagnostic Use
The CD10 antigen is a metalloendopeptidase which inactivates a number of
biologically active peptides. It is expressed on a wide variety of normal and
neoplastic tissues of both lymphoid and nonlymphoid origin. CD10 antigen
has been identified on cells of lymphoblastic, Burkitt's and follicular
lymphomas and on the cells of patients with chronic myeloid leukemia.
Product Specific Information
CD10 (56C6) is recommended for the differential diagnosis of small B cell
lymphoma and the subtyping of lymphoblastic leukemia.
Also available as a Novocastra concentrate, refer to page 73.
Tonsil: immunohistochemical staining with Bond ready-to-use CD10 (56C6) using Bond Polymer
Refine Detection.
CD11c
Clone 5D11
7 mL Bond ready-to-use PA0554 P (HIER)
For In Vitro Diagnostic Use
CD11c is a member of the leukocyte integrin family of adhesion proteins
expressed in normal cells, with high levels on tissue macrophages and
monocytes with weak staining of granulocytes. CD11c antigen has been
described on NK cells, activated T cells, lymphoid cell lines including hairy
cell leukemia and a proportion of interdigitating dendritic cells.
Product Specific Information
Bond ready-to-use CD11c (5D11) is recommended for use as part of a panel
of antibodies in the diagnosis of hematological malignancies and identification
of cells of the macrophage/dendritic cell lineage in tissues.
Also available as a Novocastra concentrate, refer to page 73.
Hairy cell leukemia: immunohistochemical staining with Bond ready-to-use CD11c (5D11) using
Bond Polymer Refine Detection.
CD15
Clone Carb-1
7 mL Bond ready-to-use PA0039 P (HIER)
For In Vitro Diagnostic Use
CD15 antigen, also known as X-hapten, is reported to be expressed on 90
percent of circulating human granulocytes, 30 to 60 percent of circulating
monocytes and is absent from normal lymphocytes. The CD15 antigen is also
expressed on Reed Sternberg cells of Hodgkin's disease and some
leukemias.
Also available as a Novocastra concentrate, refer to page 74.
Hodgkin’s lymphoma: immunohistochemical staining with Bond ready-to-use CD15 (Carb-1)
using Bond Polymer Refine Detection.
F Frozen I Immunofluorescence E Electron microscopy
P Paraffin C Flow cytometry O Other applications
W Western blotting
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Bond