Angelika Semmler - KOPS - Universität Konstanz

Peptid 11
Fmoc-Ala-Gly-Pro-Gly-Phe-Glu(OAll)-Lys(Boc)-NH2
Analytische RP-HPLC (Nucleosil Säule): (10-85% B in 30 min, 1 ml/min)
RP-HPLC / tR MALDI-TOF-MS gemessen [M+X] + berechnet
8 Experimenteller Teil
24,1 min 1088,8 m/z [M+Na] + 1088,50 m/z (C55H71N9NaO13 + )
20,0 min 966,9 m/z [(M-Boc)+H] + 966,47 m/z (C50H64N9O11 + )
Fmoc-Pll-Ala-Gly-Pro-Gly-Phe-Glu(OAll)-Lys-NH2
Analytische RP-HPLC (Nucleosil Säule): (10-85% B in 30 min, 1 ml/min)
RP-HPLC / tR MALDI-TOF-MS gemessen [M+X] + berechnet
19,9 min 1247,0 m/z [(M+H] + 1246,57 m/z (C63H80N11O16 + )
Cyclo[Pll-Ala-Gly-Pro-Gly-Phe-Glu]-Lys(Boc)-NH2 (11)
Analytische RP-HPLC (Nucleosil Säule): (10-85% B in 30 min, 1 ml/min)
RP-HPLC / tR ESI-MS gemessen [M+X] + berechnet
18,2-18,4 min 1088,4 m/z [M+Na] + 1088,50 m/z (C50H71N11NaO15 + )
14,2-14,8 min 966,4 m/z [(M-Boc)+H] + 966,46 m/z (C45H71N11O13 + )
Peptid 12
Fmoc-Gly-Ala-Phe-Gly-Pro-Glu(OAll)-Lys(Boc)-NH2
Analytische RP-HPLC (Nucleosil Säule): (10-85% B in 30 min, 1 ml/min)
RP-HPLC / tR MALDI-TOF-MS gemessen [M+X] + berechnet
24,0 min 1088,6 m/z [M+Na] + 1088,50 m/z (C55H71N9NaO13 + )
19,9 min 966,8 m/z [(M-Boc)+H] + 966,47 m/z (C50H64N9O11 + )
Fmoc-Pll-Gly-Ala-Phe-Gly-Pro-Glu(OAll)-Lys-NH2
Analytische RP-HPLC (Nucleosil Säule): (10-85% B in 30 min, 1 ml/min)
RP-HPLC / tR MALDI-TOF-MS gemessen [M+X] + berechnet
20,1 min 1246,5 m/z [M+H] + 1246,57 m/z (C63H80N11O16 + )
Cyclo[Pll-Gly-Ala-Phe-Gly-Pro-Glu]-Lys(Boc)-NH2 (12)
Analytische RP-HPLC (Nucleosil Säule): (10-85% B in 30 min, 1 ml/min)
RP-HPLC / tR ESI-MS gemessen [M+X] + berechnet
18,1-18,3 min 1088,4 m/z [M+Na] + 1088,50 m/z (C50H71N11NaO15 + )
14,1-14,7 min 966,4 m/z [(M-Boc)+H] + 966,46 m/z (C45H71N11O13 + )
133