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Vol.XXXVII, Suppl. 1 - Giornale Italiano di Ortopedia e Traumatologia

Vol.XXXVII, Suppl. 1 - Giornale Italiano di Ortopedia e Traumatologia

Vol.XXXVII, Suppl. 1 - Giornale Italiano di Ortopedia e Traumatologia

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s108<br />

concLusioni<br />

Dalle nostre osservazioni e dalla letture dei numerosi<br />

lavori conclu<strong>di</strong>amo che le superfi ci rugose migliorano<br />

l’adesione e l’integrazione tra interfaccia e substrato. La<br />

sabbiatura del titanio garantisce una migliore aderenza<br />

ed una minore delaminazione delle superfi ci con una<br />

minore produzione <strong>di</strong> detriti. D’altra parte, i rivestimenti<br />

<strong>di</strong> titanio sabbiato a causa della ruvi<strong>di</strong>tà dell’interfaccia<br />

concedono un aumento della coesione tra l’interfaccia <strong>di</strong><br />

rivestimento ed il substrato. La ricerca della migliore geometria<br />

delle protesi e del materiale più biocompatibile è<br />

continua e molti stu<strong>di</strong> hanno concentrato l’attenzione sui<br />

Bibliografi a<br />

1 Matsusue Y, Yamamuro T, Oka M, et al. In<br />

vitro and in vivo stu<strong>di</strong>es on bioabsorbable<br />

ultra-high-strength poly(L-lactide) rods. J<br />

Biomed Mater Res 1992;26:1553-67.<br />

2 Cochran DL, Schenk RK, Lussi A, et al. Bone<br />

response to unloaded and loaded titanium<br />

implants with a sandblasted and acid-etched<br />

surface: a histometric study in the canine man<strong>di</strong>ble.<br />

J Biomed Mater Res 1998;40:1-11.<br />

3 Thomas KA, Cook S. An evaluation of<br />

variables infl uencing implant fi xation by <strong>di</strong>rect<br />

bone apposition. J Biomed Mater Res<br />

1985;19: 875-901.<br />

4 Wilke HJ, Claes L, Steinemann S. The infl uence<br />

of various titanium surfaces on the interface<br />

shear strength between implants and<br />

bone. In: Heimke G, Soltesz U, Lee AJC, eds.<br />

Advances in biomaterials:clinical implant<br />

materials. Amsterdam: Elsevier Science Publishers<br />

1990, pp. 309-14.<br />

5 Klokkevold, PR, Nishimura RD, Adachi M,<br />

et al. Osseointegration anhanced by chemical<br />

etching of the titanium surface: a torque<br />

removal study in the rabbit. Clin Oral Implants<br />

Res 1997;8:442-7.<br />

6 Buser D, Schenk RK, Steinemann S, et al.<br />

Infl uence of surface characteristics on bone<br />

V. ZottoLa Et aL.<br />

integration of titanium implants. a histometric<br />

study in miniature pigs. J Biomed Mater Res<br />

1991;25:889-902.<br />

7 Weingart D, Steinemann S, Schilli W, et al.<br />

Titanium deposition in regional lymph nodes<br />

after insertion of titanium screw implants in<br />

the maxillofacial region. Int J Oral Maxillofac<br />

Surg 1994;23:450-2.<br />

8 Cochran DL, Simpson J, Weber HP, et al. Attachment<br />

and growth of periodontal cells on<br />

smooth and rough titanium. Int J Oral Maxillofac<br />

Implants 1994;9:289-97.<br />

9 Boyan BD, Batzer R, Kieswetter K, et al. Titanium<br />

surface roughness alters responsiveness of<br />

mg 63 osteoblast-like cells to 1_,25-(oh)2d3.<br />

J Biomed Mater Res 1998;39:77-85.<br />

10 Martin JY, Dean DD, Cochran DL, et al. Proliferation,<br />

<strong>di</strong>fferentiation, and protein synthesis<br />

of human osteoblast-like cells (mg63)<br />

cultured on previously exposed titanium surfaces.<br />

Clin Oral Implants Res 1996;7:27-<br />

37.<br />

11 Hermann JS, Cochran DL, Pirkka V, et al. Crestal<br />

bone changes around titanium implants.<br />

a ra<strong>di</strong>ographic evaluation of unloaded nonsubmerged<br />

and submerged implants in the<br />

canine man<strong>di</strong>ble. J Periodontol 1997;68:<br />

1117-30.<br />

trattamenti <strong>di</strong> sabbiatura della superfi cie degli impianti in<br />

lega <strong>di</strong> titanio. Clinicamente, gli effetti della tecnica operatoria,<br />

il <strong>di</strong>segno dell’impianto e le proprietà dei materiali<br />

hanno un importante effetto biologico sull’integrazione,<br />

sulla durata e sulla stabilità della protesi dal momento<br />

che il trattamento <strong>di</strong> sabbiatura infl uenza la cinematica<br />

che appare essere secondaria alla qualità ed alla quantità<br />

dell’integrazione biologica dell’impianto. Dalla lettura<br />

dei <strong>di</strong>versi stu<strong>di</strong> e dalla nostra esperienza la sabbiatura<br />

della superfi cie <strong>di</strong> un impianto in lega <strong>di</strong> titanio aumenta<br />

la formazione ossea sulle superfi ci e migliora l’adesione<br />

dell’interfaccia paragonabile ai rivestimenti porosi.<br />

12 Arys A. Philippart C. Dourov N. et al. Analysis<br />

of titanium dental implants after failure<br />

of osseointegration: combined histological,<br />

electron microscopy, and X-ray photoelectron<br />

spectroscopy approach. J Biomed Mater<br />

Res1998;43:300-12<br />

13 Wong M, Eulenberger J, Schenk RK, et al. Effect<br />

of surface topography on the osseointegration<br />

of implant materials in trabecular bone. J<br />

Biomed Mater Res 1995;29:1567-75.<br />

14 Buser D, Nyddeger T, Oxland T, et al. The<br />

interface shear strength of titanium implants<br />

with a sanblasted and acid-etched<br />

surface. a biomechanical study in the maxilla<br />

of miniature pigs. J Biomed Mater Res<br />

1999;32:1657-755.<br />

15 Wilke HJ, Claes L, Steinemann S. The infl uence<br />

of various titanium surfaces on the interface<br />

shear strength between implants and<br />

bone. In: Heimke G, Soltesz U, Lee AJC, eds.<br />

Advanced in biomaterials: clinical implant<br />

materials. Amsterdam: Elsevier Science Publishers<br />

1990, p. 309-14.<br />

16 Aronsson B-O, Hjörvarssojn B, Frauchiger L,<br />

et al. Hydrogen desorption from sand-blasted<br />

and acid-etched titanium surfaces after<br />

glow-<strong>di</strong>scharge treatment, J Biomed Mater<br />

Res 2001;54:20-9.

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