n - Кафедра Прикладная биотехнология

(Cushnie and Lamb, 2005). Our data for oak honeydew honeys from Bulgaria confirm
findings of high antibacterial activity in some honeydew honeys.
It is well known that the greater part of the antibacterial activity of honey is due to
hydrogen peroxide (Bang et al., 2003). This activity attributed to honey glucose peroxidase
system (Molan, 1992; Bogdanov, 1997). For example, in the moment it is well
known that almost all resistant for antibiotics Staphylococcus spp. has enzyme catalase,
with potentiality for destruction of hydrogen peroxide (Carter et al., 1995). But we
don’t know the quantity of catalase in these microorganisms, some of them with great
responsibility for pets and humans health (Lloid, 2007). It is conceivable that absence of
catalase in different honeydew honeys might be the «unique factor» which differentiates
«active» from «inactive» honeys (Weston, 2000). To prove this view, additional surveys
with more samples honeydew honeys from different geographical origins need to determine
the levels of all antibacterial and antioxidant activities.
antibacterial activity
45
40
35
30
25
20
15
10
5
0
270
y = 0.1441x + 33.05
R 2 = 0.2289
0 5 10 15 20 25 30 35 40
antioxidant activity
Correlation between antibacterial and antioxidant actiity
If summarize data from our experiments we could conclude that some oak honeydew
honeys could have potential antibacterial effect against resistant for antibiotics
strains of microorganisms. In this reason more simultaneously investigations into the
mode of action of the antibacterial and antioxidant activities of some types of honeys,
especially oak honeydew honeys are warranted, as these may lead to new sources of antibacterial
therapeutics for resistant microorganisms.
The bibliographic list
1. Allen, K.L. A survey of the antibacterial activity of some New Zealand honeys / K.L. Allen,
P.C. Molan, G.M. Reid // J Pharm Pharmacol. 43(12), 1991. – P. 817–822.
2. Al-Mamary, M. Antioxidant activities and total phenolics of different types of honey / M. Al-
Mamary, Ali Al-Meeri, M. Al-Habori // Nutrition Research, 22, 2002. – P. 1041–1047.
3. Badawy, O.F.H. Antibacterial activity of bee honey and its therapeutic usefulness against
Escherichia coli O157:H7 and Salmonella typhimurium infection / O.F.H. Badawy, S.S.A. Shafii,
E.E. Tharwat, A.M. Kamal // Revue Scientifique et Technique-Office International des Epizooties 23,
2004. – Р. 1011–1022.
4. Bang, L.M. The effect of dilution on the rate of hydrogen peroxide production in honey and its
implications for wound healing / L.M. Bang, C. Buntting, P. Molan // J.Altern.Complement Med. 9 (2),
2003. – Р. 267–273.