Conference Proceedings - School of Nursing & Midwifery - Trinity ...

School of Nursing & Midwifery, Trinity College Dublin: 8 th Annual Interdisciplinary Research Conference
Transforming Healthcare Through Research, Education & Technology: 7 th – 9 th November 2007
Conference Proceedings
Although many more males were approached to take part in this
study they refused as they were already participating in other
clinical trials, thus accounting for the high proportion of females to
males. All but three of the participants were white middle-aged
British citizens. The other three were originally from China. All
participants received adjuvant chemotherapy on either a weekly or
three weekly basis. Thirty three of the females received FEC
chemotherapy (44.7% in the control group and 51.5% in the
intervention group) on a three weekly basis. Sixteen females
received epirubicin and CMF (28.9% in the control group and 15.2%
in the intervention group) on a three weekly basis. One female
received CMF only and her data is included with the EpiCMF group of
patients. She refused to have epirubicin due to the high risk of hair
loss. Twenty one patients received 5FU chemotherapy (26.3% in the
control group and 33.3% in the intervention group) on a weekly
basis; eight were male and thirteen were female.
Findings
1 Analysis of quantitative data (Quality of life
questionnaires)
Summary of results
Using a t-test to explore the relationship of the mean scores at
baseline between the treatment and control groups on vomiting,
nausea, anxiety, depression, psychological, physical and quality of
life from subscales from the HADS and RSCL, no statistically
significant difference was noted at the 5% level (p-value