asistirana reproduktivna tehnologija u humanoj reprodukciji

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402 A Adultne stem }elije, 377, 378 AIH -artificial insemination by husband, 356 alelomorfa, 243 Alternativne metode le~enja, 100, 173 AMH - anti-Mullerian hormone, 295, 304 Analiza ejakulata, 162 aneuploidnost, 31,32,186,188,189,190, 192,193,194,208,209,221,233,246,256, 275,276,288,289,291,292,296,299,301, 301, 302, 303,304,305,306, Angelman-ovog sindroma, 4,75, 222, 223 Anomalije kariotipa prenatalne dijagnoze, 245 APC - anaphase promoting complex, 297, 299 apoptoze oocita, 303 ARDS - acute respiratory distress syndrome, 326 Arteficijalna inseminacija, 213, 214 Asistirani hatching, 204 Asistirani hatching laserom, 204 ATP - adenosine triphosphate, 49, 50, 51, 189, 295, 300 Autoreinfuzije aspirisane te~nosti, 325 AZF - azoospermia factors, 220, 236, 237 AZFc-azoospermia factors, 237, 240, 241 B balansirane translokacije, 245, 246, 335 birefrigence, 373 Body mass index, 113, 181, 307, 308 BWS - Beckwith Wiedemann syndrome, 74, 75, 222, 223 C CBAVD - congenital bilateral absence of the vas deferens, 217, 218, 220 CBG - corticosteroid binding globulin, 250, 261, 262 INDEX Centrozoma spermatozoida, 165 CFTR – cystis fibrosis transmembrane conductance regulator gen, 220 checkpoint control, 297, 299 Citokini, 40, 87, 88, 101, 113 CK – kreatin kinaze, 189, 195 CL - corpus luteum, 42, 54, 55, 56, 79, 80, 178, 180, 211, 254, 259, 260, 327 Coasting – tehnika, 327 COS - kontrolisana stimulacija ovarijuma, 180, 181 Cryoloop, 285, 286 CSF - cytostatic factor, 298, 299 CVS - chorionic villus sampling, 208, 221 D DAZ - deleted in azoospermia homolog gen, 236, 237, 239, 240, 241, 242, 248 DAZ - deleted in azoospermia homolog genski cluster, 236 DBY - dead box Y chromosome gen, 237, 238, 242 delecija, 217, 236, 237, 242, 243, 245, 248, 333, 340 DMAP - 6-dimetilaminopurina, 38, 228 DMSO – dimethyl sulfoxide, 281, 283 Donacija gameta i embriona, 313, 314,382 Down-ov sindrom, 207, 292, 333, 339 E E mi1, 299 EBM - evidenciono bazirana medicina, 167 EBSS - Earle's balanced salt solution, 368 EDTA- ethylenediaminetetraacetic acid, 190 EG - ethylene glycol, 283, 284 EGF - epidermal growth factor, 86, 87, 88, 229, 230, 231, 253, 368 EIM- european IVF- monitoring programe, 355
Index ejakulirani spermatozoidi, 217 ekspresije i raspodele genskih produkata, 301 Ekstra-peritonealna insuflacija gasa, 158 Ektopi~na trudno}a, 317 Elektivna redukcija fetusa, 331, 352 Elektrokauterizacija ili laser vaporizacija jednog ili oba ovarijuma, 328 embrionski markeri implantacije, 250 Embriotransfer,186, 208, 210, 211, 280, 317, 345, 354, 356 equilibrium freezing, 277 eSET elective single embryo transfer, 354 Estradiol, 35, 41, 55, 57, 58, 60, 79, 83, 118, 121, 126, 183,184, 186, 207, 214 EUFA- early unilateral folicular aspiration, 327 evolucije X homologih gena Y hromozoma, 243 evolucije X i Y hromozoma, 239, 242, 244 evolucioni mehanizam degeneracije Y hromozoma, 243 F Faktori rasta, 39,40, 49, 53, 86, 87, 88, 229, 251, 300, 368 FbM - filled by mass tehnika, 181 Fertilizacija, 57, 177,178, 188, 197, 252, 254, 267, 276, 318 Fetus, 35, 69, 77, 106,107,110, 118, 119, 128,147,187,289, 300, 302, 331, 352, 376 FF - follicle fluid, 259 FF- MAS - follicular fluid meiosis activating sterol, 231, 232, 301 FI - flow index, 152, 260 FISH - fluorescence in situ hybridization, 31, 32, 33, 191, 192, 195, 207, 296 fizikalne metode le~enja, 173 Flexipet-denuding pipette, 285 Flow index, 309, 310 FNA - fine needle aspiration, 219 folikularni markeri implantacije, 250,251 follicle dysfunction, 311 FOXL2 - forkhead transcription factore gene, 304 fragmentacija, 53,166, 198, 199, 200, 201, 259, 286 fresh embrio transfer, 280 FSH - follicle stimulating hormone, 35,37,47, 48, 51, 54, 55, 57, 58, 116,117, 121,124, 126,136,137,138,140,142,143, 144, 153,171,178,179,180,181,182,186, 205,207,214,228,228, 230, 231,251, 252, 254,255, 301, 302,303, 304,307,309, 310, 311, 319, 328 G Gasna embolija, 156, 159 GDF-9 - growth differentiation factor 9, 304 gene chip tehnology, 304 GM-CSF – granulocyte macrophage colony stimulating factor, 260 GnRH agonisti, 124, 125, 179, 180, 184, 186, 211, 303, 327 GnRH antagonisti, 100, 180, 186 Gradijentna separacija, 192, 193 GTP - guanosine triphosphate, 295 gustinski gradijent, 189, 190, 191 GVBD - germinal vesicle breakdown, 37, 38, 39, 118, 226, 228, 232, 294 H 403 HA – hyaluronic acid, 189, 193, 194, 195 HAES - hydroxyethyl starch rastvor, 325 HB-EGF - heparin binding epidermal growth factor, 87, 368 HCG Humani horionski gonadotropin, 34, 56,87,118,127,179,180,184,186,187,211, 214,215,228,229,230,231,233,251,252, 253,255,259,265,267,306,318,319,320, 323,327,328, HEPA-high efficiency particulate air filtraciju, 362, 363 hESC -human embryonic stem cell, 378, 379, 380, 381 heterotopi~ne autotransplantacije, 282 hialuronat, 367, 368 Hidrosalpinks, 329, 330 high response, 307 Hirur{ki pristup OHSS, 326 Histerosalpingogram, 329 Histeroskopija, 161 HMG- humani menopauzalni gonadotropin, 179, 180, 214, 255, 302 HOS- hypoosmotic swelling test, 275 HPLC- high performance liquid chromatography, 181 HSET - kinesin related protein, 295 HSP70 - heat shock protein, 303 HspA2 - heat shock 70kDa protein 2, 188, 190 Humani X hromozom, 234 Humani Y hromozom, 235, 243
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E L I T • M E D I C A ASISTIRANA
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SLOBODAN R. RADULOVI] ASISTIRANA RE
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SARADNICI BOJANA SAVI]EVI], dr sci
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PREDGOVOR Knjiga "Asistirana reprod
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U knjizi se ukazuje i na sve ~e{}e
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DEO III STERILITET ................
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I DEO ISTORIJAT
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4 Sl. 1.2.- Hipokrat Sl. 1.3.- Aris
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6 Sl. 1.8.- Andreas Vesalius Sl. 1.
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8 Sl. 1.15.- Jajna }elija prikaz Al
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10 Sl. 1.23.- Gregor Mendel Sl. 1.2
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12 Sl. 1.30.- Gregory Goodwin Pincu
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14 Sl. 1.39.- Joe Hin Tjio Sl. 1.40
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16 1987. godina: Predloèn je proje
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II DEO HUMANA REPRODUKCIJA
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22 Metafaza: Formira se ekvatorijal
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24 1.1. OOGENEZA Oogeneza je proces
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26 prisutna je kod rastu}ih oocita
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28 Po zavr{etku profaze prve mejoti
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30 Sumiraju}i proces mejoze moè se
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32 Podaci o hromozomskim abnormalno
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34 lo{om prognozom u IVF - in vitro
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36 mejozu tokom drugog tromese~ja t
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38 factor-a i dovodi do degradacije
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40 Citokini su se nekada dovodili u
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42 za ljudske granulozne }elije u i
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44 Sl. 2.22 - De Graff - ov folicul
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46 kroz membranu. Materijali rastvo
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48 na u toku rasta oocita kulminira
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50 Centralna stvar za uspe{no imple
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52 Navedene fundamentalne osobine s
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54 growth factor, BDNF - brain deri
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56 kapilara. Ova mreà kapilara, u
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58 Koncentracija luteiniziraju}eg h
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60 du` Falopijeve tube. Stimulus je
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62 Spermatozoid istovremeno osloba|
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64 fazama igra va`nu ulogu. Kinozil
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66 Sl. 2.52- Po~etak sinteze DNK -
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68 2.9. MIGRACIJA EMBRIONA KROZ TUB
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70 uspe{nije. Suprotno ovome, mu`ja
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72 prona|en kod spermatozoida, dok
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74 Nakon oplodnje se oba roditeljsk
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76 koji sadrì metil-vezuju}i domen
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78 Endometrium sadrì mnogobrojne `
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80 U kasnoj folikularnoj fazi zadeb
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82 uzvi{enja se sastoji u absorpcij
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84 Sl. 2.77- Po~etak nidacije U ovo
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86 Sl. 2.83- a) Implantacija 9 - 10
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88 IGFB 1 - insulin like growth fac
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90 Asistirana reproduktivna tehnolo
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Nemogu}nost da se imaju sopstvena d
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III Deo: Sterilitet 95 1.1. MIOMI I
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III Deo: Sterilitet 97 Koriste se p
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III Deo: Sterilitet 99 Sl. 3.8- PR
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III Deo: Sterilitet 101 Brojne stud
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III Deo: Sterilitet 103 Infekcija ~
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III Deo: Sterilitet 105 Sl. 3.19- C
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III Deo: Sterilitet 107 Odre|ivanje
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III Deo: Sterilitet 109 Sl. 3.27- H
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III Deo: Sterilitet 111 Radi spre~a
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III Deo: Sterilitet 113 Poreme}aj m
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III Deo: Sterilitet 115 ciju insuli
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III Deo: Sterilitet 117 Centralna u
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III Deo: Sterilitet 119 je vaàn as
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III Deo: Sterilitet 121 kod pacijen
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III Deo: Sterilitet 123 Vrednost pr
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III Deo: Sterilitet 125 dijabetesa
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III Deo: Sterilitet 127 koncentraci
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III Deo: Sterilitet 129 Upotreba ne
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III Deo: Sterilitet 131 Sl. 3.44- I
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III Deo: Sterilitet 133 kore nadbub
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III Deo: Sterilitet 135 2. POREME]A
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III Deo: Sterilitet 137 U drugom ob
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III Deo: Sterilitet 139 tumora koji
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III Deo: Sterilitet 141 Sl. 3.47- A
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III Deo: Sterilitet 143 O{te}enje z
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III Deo: Sterilitet 145 2.3. POSTTE
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III Deo: Sterilitet 147 Kako nisu d
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III Deo: Sterilitet 149 Postupci as
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III Deo: Sterilitet 151 procenu sek
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III Deo: Sterilitet 153 pouzdan i s
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III Deo: Sterilitet 155 {to je nedo
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III Deo: Sterilitet 157 Komplikacij
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III Deo: Sterilitet 159 Gasna embol
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III Deo: Sterilitet 161 Pelvi~na in
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III Deo: Sterilitet 163 Sve ve}i br
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III Deo: Sterilitet 165 Rep treba d
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III Deo: Sterilitet 167 3.3. PREGLE
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III Deo: Sterilitet 169 reprodukcij
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III Deo: Sterilitet 171 Jasna indik
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III Deo: Sterilitet 173 Reproduktiv
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IV Deo: Asistirana reproduktivna te
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Page 365 and 366: IV Deo: Asistirana reproduktivna te
Page 401 and 402: LITERATURA Abdul-Jalil, A., Child,
Page 403 and 404: Literatura Blumenfeld Z, Response o
Page 405 and 406: Literatura Hum. Reprod. 17: 2621-26
Page 407 and 408: Literatura Hippenstiel, S., Soeth,
Page 409 and 410: Literatura dehydrogenase in human s
Page 411 and 412: Literatura fibroid reduction and sy
Page 413 and 414: Literatura Tease, C, Hartshorne, G.
Page 415: Literatura follicular growth, and o
Page 419 and 420: Index ODS -ovarijalni dehidrogenazn
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asistirana reproduktivna tehnologija u humanoj reprodukciji

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