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RATL: A Database of Reptile and Amphibian Toxicology Literature

RATL: A Database of Reptile and Amphibian Toxicology Literature

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Contaminant a Species<br />

Code b<br />

Lifestage Exposure<br />

Route f<br />

Table 4 - Laboratory Studies - 16<br />

Study<br />

Endpoint g Temp h pH Contaminant<br />

Concentration<br />

e<br />

Results, Residues, Effects <strong>and</strong>/or Remarks d,e<br />

Reference k<br />

Congo red XELA embryo IMMER MORT 0-1000 mg/L Death <strong>and</strong> defects were noted in embryos exposed for 4 d<br />

post-fertilization.<br />

Daston et al. 1991<br />

copper sulfate RACY adult INJECT PHYSIO 100-200 µg Progressive reduction in total number <strong>of</strong> blood cells following<br />

Patil <strong>and</strong> Shivaraj 1984<br />

i.m. injection <strong>of</strong> 100 <strong>and</strong> 200 µg CuSO 4 for 40 d. White blood<br />

cells increased for first 7 d then gradually decreased.<br />

Hemoglobin reduced.<br />

k<br />

copper sulfate RAPI adult IMMER MORT 4.9-5.7 0.0001- 0.1 % 100 % mortality > 0.005%; 100% survival < 0.0015 %.<br />

Kaplan <strong>and</strong> Yoh 1961 k<br />

copper sulfate RAPI egg INJECT MORT 0.04-1.56<br />

mg/L<br />

No effect.<br />

L<strong>and</strong>é <strong>and</strong> Guttman 1973 k<br />

copper sulfate RAPI tadpoles INJECT MORT 0.04-1.56<br />

mg/L<br />

0.31 mg/L was fatal to tadpoles. Weights <strong>of</strong> tadpoles grown<br />

in 0.06 or 0.16 mg/L were lower than controls.<br />

L<strong>and</strong>é <strong>and</strong> Guttman 1973 k<br />

copper sulfate XELA adult (F) IMMER MORT 22 5.2-5.7 0.0005% - At conc. <strong>of</strong> 0.0015%: 11/16 died within 24 d; at conc. <strong>of</strong> Fingal <strong>and</strong> Kaplan 1963<br />

0.10% 0.002%: 100% mortality occurred within 15 d.<br />

copper sulfate XXXA juvenile IMMER 2 ppm. Abnormalities observed<br />

in pigmentation, tail fin <strong>and</strong> alimentary canal.<br />

Abbasi <strong>and</strong> Soni 1984 k<br />

Cr, Zn, Fe PLXX larvae IMMER GENOTOX 0-2.5 mg/L Sig. number <strong>of</strong> genotoxicity effects, more dramatic than Godet et al. 1996<br />

crude oil CACA juvenile ENVIRON BEHAV<br />

(Cr)/0-25 mg/L when metals were tested alone.<br />

(Fe)/0- 0.75<br />

mg/L (Zn)<br />

Results not extracted from paper. Vargo et al. 1986<br />

crude oil CHMY juvenile ENVIRON BEHAV Limited ability to avoid oil slicks; respiration, skin, blood<br />

chemistry <strong>and</strong> salt gl<strong>and</strong> function sig. affected. Oil in ears,<br />

eyes, esophagus <strong>and</strong> feces.<br />

Vargo et al. 1986<br />

crude oil RAAR embryo IMMER DEVOBS 0.25-1.00 ml/L Highest embryonic mortality at 0.75 ml/L. All hatched larvae Pyastolova <strong>and</strong> Danilova<br />

died within a few days 0.25 ml/L 88% <strong>of</strong> larvae died within<br />

first wk.<br />

1986 k<br />

Cs COCO adult RAD PHYSIO Results not extracted from paper. Staton et al. 1974<br />

Cs ELOB adult RAD PHYSIO Results not extracted from paper. Staton et al. 1974<br />

Cs LAGE adult RAD PHYSIO Results not extracted from paper. Staton et al. 1974

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