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RATL: A Database of Reptile and Amphibian Toxicology Literature

RATL: A Database of Reptile and Amphibian Toxicology Literature

RATL: A Database of Reptile and Amphibian Toxicology Literature

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Contaminant a Species<br />

Code b<br />

Lifestage Exposure<br />

Route f<br />

Table 4 - Laboratory Studies - 42<br />

Study<br />

Endpoint g Temp h pH Contaminant<br />

Concentration<br />

e<br />

Results, Residues, Effects <strong>and</strong>/or Remarks d,e<br />

Reference k<br />

mesotocin AMTI larvae IMMER PHYSIO Mesotocin restored glomerular filtration rate to 148 after<br />

vasotocin caused a decrease from 127 to 92 µl/10g/h.<br />

Stiffler et al. 1981<br />

mesotocin NOVI adult INJECT PHYSIO 5 ng/g Results not extracted from paper. Hartenstein <strong>and</strong> Stiffler 1981<br />

mesotocin TAGR adult INJECT PHYSIO 5 ng/g Mesotocin (a possible diuretic in adult salam<strong>and</strong>ers) caused<br />

glomerular filtration rate to increase from 0.136 to 0.171<br />

ml/10g/h. (not a sig. increase).<br />

Hartenstein <strong>and</strong> Stiffler 1981<br />

metal oxides PLWA larvae IMMER GENOTOX 125 ml/L, 250 High numbers <strong>of</strong> micronucleated erythrocytes (22/1000 Gauthier et al. 1993<br />

ml/L <strong>of</strong> river<br />

water<br />

erythrocytes).<br />

metals XXFR embryo IMMER MORT various Increased conc. resulted in increased incidence <strong>of</strong><br />

Mironova <strong>and</strong> Andronikov<br />

abnormalities in embryos; higher mortality in earliest<br />

embryogenic stages.<br />

1992<br />

metals XXXA tadpoles IMMER MORT Increased incidence <strong>of</strong> malformations from laboratory<br />

exposures to reservoir surface water samples with increasing<br />

metals conc. Effects observed were associated with Cu, Cd <strong>and</strong><br />

Zn.<br />

Pascoe et al. 1994<br />

metals XXXA tadpoles IMMER MORT Results <strong>of</strong> surface water analysis were spatially variable; no<br />

statistically sig. acute toxicity found in tadpoles after 96 h.<br />

Linder et al. 1994<br />

methallibure TAGR adult (M) IMMER PHYSIO 1 mg Methallibure sig. reduced the <strong>and</strong>rogen levels. Moore 1977<br />

methane sulfonate BUMA adult TISPREP PHYSIO 37 Sulfide <strong>and</strong> sulfoxide showed no response curve to ACh;<br />

sulfone <strong>and</strong> phystigmine showed cumulative conc. response<br />

curve to ACh.<br />

Smith et al. 1996<br />

methane sulfonate RAPI adult INJECT PHYSIO 150 body wt Produced a flaccid paralysis <strong>and</strong> loss <strong>of</strong> the righting reflex in a Wayson et al. 1976<br />

number <strong>of</strong> species, including the frog. Frog regained righting<br />

reflex after 113 min on avg.<br />

methomyl EUOS adult INHAL MORT 1-2% 1-3 h lethal time. Kihara <strong>and</strong> Yamashita 1978<br />

methoprene BUBO juvenile IMMER PHYSIO 23-24 100 ppb Lowered temp. tolerance.<br />

Johnson <strong>and</strong> Prine 1976 k<br />

methoprene BUBO tadpoles IMMER MORT 22-26 1 No adverse effects were observed, 0% mortality at 1 ppm. Miura <strong>and</strong> Takahashi 1973<br />

methoprene BUBU tadpoles IMMER DEVOBS 10 Inhibitory effect upon development in both amphibian <strong>and</strong><br />

domestic chicken eggs.<br />

Paulov 1976<br />

methoxychlor ALMI adult TISPREP DEVOBS No interaction with estrogen receptors. Vonier et al. 1996<br />

methoxychlor AMMA embryo IMMER HATSUC

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