RATL: A Database of Reptile and Amphibian Toxicology Literature

Contaminant a Contaminant
b
Concentration
b
LC50
fluoranthene, UV 0, 25, 125, 250,
625 µg/L
fluoranthene, UV 0, 25, 125, 250,
625 µg/L
EC50 b
TI d
Table 5 - FETAX Studies - 10
MCIG d
NOEL d
LOEL d
Effects/Notes de
UV exposure alone cause brown
pigmentation on skin. UV + PAH
exposure resulted in inhibited growth and
40% mortality at 125 µg/L of
fluoranthene and 100% mortality at
1250 µg/L of fluoranthene.
UV exposure alone caused brown
pigmentation on skin. UV + PAH
exposure resulted in inhibited growth and
40% mortality at 125 µg/L of
fluoranthene and 100% mortality at
1250 µg/L of fluoranthene.
fluorouracil 0.53 mg/L 0.08 6.63 Malformations included abnormal gut,
face, eye, brain, heart, spine formation
(0.01 mg/L).
fluorouracil 0.71 - 1.9 0.038 - 6.7 - 18.7 0.05 -
0.122
0.125
fluorouracil 1.22 - 0.120 - 10.16 - 0.0875 -
1.62 0.137 11.82 0.120
fluorouracil 0.08 mg/mL Tested alone at this conc. Fuorouracil
exhibited 24% malformation in survivors
(1.9% mortality). Coadministration of
caffeine, theophylline, and theobromine
greatly increased the incidence of
malformed embryos (85.7%, 87.8% and
42.5% respectively).
formamide 0.25-1.75% v/v 1.04% v/v
(pooled
trials)
1.26, 0.83,0.97
1.06% v/v (trials
(trials separate)
separate)
0.75, 0.5%
v/v (trials
separate)
Most toxic solvent. NOEL values for
mortality and length were: 1.0, 0.5% v/v
(mortality), 0.75, 1.0% v/v (length).
Reference k
Hatch & Burton 1996
Hatch & Burton 1998
DeYoung et al. 1996
Bantle et al. 1994b
Dawson and Bantle 1987b
Dawson and Bantle 1987a
Dresser et al. 1992
fuel oil blend 1.48 % 0.96 %
Dumont et al. 1983 k
Garlon 3A 100 mg/L No significant effects up to 100 mg/L for
formulated triclopyr.
Perkins 1995
gentisic acid 10839.5 1531.8
Schultz and Dawson 1995
mg/L mg/L
mean mean
glycerol formal 0.25-1.75% v/v 1.65, 1.09, 1.51,1.37 0.50% v/v
NOEL values for mortality and length Dresser et al. 1992
1.57% v/v 1.15% v/v
(malform.)
were: 1.25, 1.0% v/v (mortality) and
0.75,