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RATL: A Database of Reptile and Amphibian Toxicology Literature

RATL: A Database of Reptile and Amphibian Toxicology Literature

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Appendix 5: Descriptions <strong>of</strong> study endpoint codes used in Tables 2, 4 <strong>and</strong> 6. Study endpoint<br />

assignments used st<strong>and</strong>ard methodology classifications <strong>and</strong> the original<br />

reference may discuss other effects <strong>of</strong> exposure not presented here. See the<br />

original reference for full details <strong>of</strong> study methodology.<br />

Study<br />

Endpoint<br />

Endpoint Term Study Endpoint Description<br />

BEHAV Behavioural observations Contaminant exposure was associated with altered behaviour (i.e.<br />

avoidance, lethargy, paralysis).<br />

DEVOBS Developmental<br />

Contaminant exposure was associated with alterations to various<br />

observations<br />

developmental processes or disruptions (i.e. growth, teratogenesis,<br />

delayed metamorphosis, polydactyly, limb regeneration). Endpoint may<br />

also refer to endocrine disrupting effects.<br />

GENOTOX DNA damage/<br />

Contaminant exposure was associated with DNA damage which may<br />

genotoxicity<br />

include increased frequencies <strong>of</strong> gamete loss due to cell death, embryo<br />

mortality (lethal mutations), cancer, heritable mutations <strong>and</strong> abnormal<br />

development.<br />

HATSUC Hatching success Contaminant exposure was associated with alterations in hatching success,<br />

hatching rate etc. <strong>of</strong> eggs/embryos.<br />

MORT Mortality observations Contaminant exposure was associated with death <strong>of</strong> animals.<br />

PATH Pathological observations Contaminant exposure was associated with various infections in animals<br />

(i.e. tumors, viruses, parasites, fungal growth).<br />

PHYSIO Physiological<br />

Contaminant exposure was associated with alterations in animal<br />

observations<br />

physiology (i.e. temperature tolerance, hematological status, ion balance,<br />

hormone level response).<br />

POPSUR Population surveys Field populations were surveyed (i.e. presence/absence, species richness<br />

<strong>and</strong> density) following exposure to contaminant(s).<br />

REPRO Reproductive<br />

Contaminant exposure was associated with altered reproductive activities<br />

observations<br />

(i.e. adult fertility, etc.).<br />

RESIDUE Tissue residues Contaminant(s) exposure resulted in residues <strong>of</strong> the contaminant(s)<br />

appearing in tissues under laboratory or field conditions.

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