RATL: A Database of Reptile and Amphibian Toxicology Literature

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Table 5 - FETAX Studies - 20 Contaminant a Contaminant b Concentration b LC50 EC50 b TI d MCIG d NOEL d LOEL d Effects/Notes de tamoxifen 10-100 µg/L Stage 60-66 embryo; no effect on tail resorption, > 100 µg/L resulted in mortality. tar 0.83 % 0.48 % theobromine 0.000075 mg/L When coadministered with: hydroxyurea (-), cytosine (-), cyclohexamide (+), emetine (+), fluorouacil (+). (+) = increase in rate of malformation compared to chemical tested alone; (-) = no significant difference in rate of malformation. theophylline 0.000075 mg/L When coadministered with: hydroxyurea (+), cytosine arabinoside (+), cyclohexamide (+), emetine (+), Fluorouracil (+). (+) = increase in rate of malformation compared to chemical tested alone; (-) = no significant difference in rate of malformation. toluene 500 mg/L 179-193 (test range) 173-217 (test range) trichloroethylene 0.24, 0.29 0.0048, 0.0023 trichloroethylene decreased 1.8 trichloroethylene increased 2.1 fold decreased 3.8 increased 1.7 fold 0.86-1.04 (test range) mortality (180-200); malformati on (146- 182); growth ( 131-164) 5, 12.6 NA, 0.02 More teratogenic than methylmercury chloride. Additive effects occurred with all solvents. EC25(96) and LC50(96) were 0.002% v/v and 0.035% v/v, respectively. Results indicated that a highly embyrotoxic epoxide intermediate, trichloroethylene oxide, formed as a result of the MFO mediated metabolism may play a significant role in the developmental toxicity of trichloroethylene in vitro. Based on TI values, embryo growth and types and severity of induced malformations, TCE was developmentally toxic. Reference k Fort and Stover 1997 Dumont et al. 1983 k Dawson and Bantle 1987a Dawson and Bantle 1987a Kononen and Gorski 1997 Rayburn et al. 1991a Fort et al. 1993 Fort et al. 1991
Table 5 - FETAX Studies - 21 Contaminant a Contaminant b Concentration b LC50 EC50 b TI d MCIG d NOEL d LOEL d Effects/Notes de Reference k triethylene glycol 2.19 - 2.75 2.0 - 2.4 1.07 - 1.2 1.7 - 1.8 Results from 3 trials. Rayburn et al. 1991b triethylene glycol 0, 1.7, 2.0% v/v 1.7% v/v TG only increased the mortality and malformation with TCE. There were additive effects for growth for all solvents with the teratogens. EC25(96) = 2.0% v/v. Rayburn et al. 1991a tryptophan 40 mg/L with 5 Treatments of malathion with Snawder and Chambers 1990 mg/L malathion tryptophan added had NAD+ levels similar to or higher than levels of controls. Incidence and severity of defects was not reduced and length and mortality were unchanged. Protein content was not altered. urethane 5580- 1660- 3.1-3.4 1000- Dawson et al. 1989 5710 1800 1500 UV, methoprene UV=190-310 Methoprene is subject to hydrolytic La Clair et al. 1998 nm degradation. UV-B 302 nm Larvae (stage 32-34); pyrimidine dimer frequency increased, directly correlated to UV-B. (
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RATL: A Database of Reptile and Amp
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RATL: A Database of Reptile and Amp
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ABSTRACT Many amphibian and reptile
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PRÉFACE De nombreuses populations
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TABLE OF CONTENTS Abstract………
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LIST OF TABLES Table 1: Contaminant
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INTRODUCTION Why is there a need fo
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Limitations of RATL The RATL databa
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Contaminant a Species Code b Lifest
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Table 1- Field Residues - 20 Contam
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Table 2 - Field Studies - 2 Contami
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Table 2 - Field Studies - 12 Contam
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Table 3: Acute toxicity values from
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Contaminant a Species Code b azinph
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Contaminant a Species Code b tar XE
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Table 4: Laboratory studies not inc
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Contaminant a Species Code b Cd AMG
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Page 223 and 224: Contaminant a Species Code b Lifest
Page 255 and 256: Table 5: FETAX data. [FETAX (Frog E
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Page 261 and 262: Contaminant a Contaminant b Concent
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Page 277 and 278: Table 6: pH study data. (Studies th
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Page 281 and 282: Species Code b Lifestage Study Endp
Page 289 and 290: Table 6 - pH Studies - 13 Species C
Page 317 and 318: Table 7: Reviews of primary literat
Page 319 and 320: Table 7 - Reviews - 3 Review Title
Page 321 and 322: Table 8 - Population Status - 2 Pop
Page 323 and 324: Table Notes Note a : see Appendix 2
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References - 2 Anderson, L.M. and R
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References - 4 Bantle, J.A., D.J. F
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References - 6 Beresford, W.A. , M.
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References - 8 Bishop, C.A, P. Ng,
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References - 10 Bragg, A.N. 1964. M
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References - 12 Burke, E.M. and F.H
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References - 14 Chattopadhyay, D.P.
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References - 16 Cooke, A.S. 1974. T
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References - 18 Dash, M.C. and A.K.
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References - 20 DeWitt, J.B., D.G.
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References - 22 Dutta, S.K. and P.
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References - 24 Elisyeyeva, K.H., H
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References - 26 Fontenot, L., C. Ro
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References - 28 Frisbie, M.P. and R
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References - 30 Godet, F., M. Babut
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References - 32 Gunther, R. and J.
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References - 34 Harfenist, A., T. P
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References - 36 Herkovits, J. and C
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References - 38 Hota, A. K. and M.C
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References - 40 Johnson, C.R. 1972a
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References - 42 Karns, D.R. 1984. T
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References - 44 Kraskowski, H.V., K
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References - 46 Leblanc, G.A. and L
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References - 48 Lotshaw, D.P. 1977.
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References - 50 Massot, M., J. Clob
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References - 52 Mendonca, M., J. Sh
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References - 54 Munro, D.F. 1949. E
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References - 56 Oliveira, E.M., D.V
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References - 58 Paulov, S. 1977b. T
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References - 60 Pierce, M.E. 1958.
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References - 62 Raj, T.P., A. Jeban
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References - 64 Rolfe, G. L., A. Ha
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References - 66 Sassaman, J.F. 1978
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References - 68 Semlitsch, R.D. and
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References - 70 Sparling, D.W., T.P
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References - 72 Surova, G.S. and A.
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References - 74 Tomar, V. and A. K.
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References - 76 Vijverberg, H.P.M.,
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References - 78 White, D.H. and A.J
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References - 80 Wyman, R.L. and J.
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Appendix 1a: Species codes in alpha
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Appendix 1a - Species Codes - 3 Cla
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Appendix 1a - Species Codes - 11 Cl
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Appendix 1a - Species Codes - 13 Cl
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Appendix 1b - Species Common Names
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Appendix 1c - Species Scientific Na
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Appendix 2a: Contaminant codes foun
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Appendix 2a - Contaminant Codes - 3
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Appendix 2b: Contaminants sorted by
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Appendix 2b - Contaminant Type - 3
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Appendix 4: Descriptions of exposur
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Appendix 6a: Glossary of Abbreviati
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Appendix 6b: Relevant biological an
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Appendix 6b - Glossary of RATL term
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RATL: A Database of Reptile and Amphibian Toxicology Literature

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