RATL: A Database of Reptile and Amphibian Toxicology Literature

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Contaminant a Species Code b Lifestage Exposure Route f Table 4 - Laboratory Studies - 18 Study Endpoint g Temp h pH Contaminant Concentration e Results, Residues, Effects and/or Remarks d,e Reference k cyclophosphamide PLWA larvae IMMER GENOTOX 0.5-10 Frequency of micronucleated erythrocytes: 0.5 ppm= 12/1000; 10 ppm= 171/1000. Fernandez et al. 1989 cyfluthrin AGAG adult IMMER PATH
Contaminant a Species Code b Lifestage Exposure Route f Table 4 - Laboratory Studies - 19 Study Endpoint g Temp h pH Contaminant Concentration e Results, Residues, Effects and/or Remarks d,e DDD CHPI adult ORAL RESIDUE 23-27 100 body wt 3, 6, 12, 24 h and 3 wks, respectively: Liver: 0.165, 0.070, 0.040, ND, 0.610. Brain: ND, 0.208, ND, ND, 1.502. Fat: ND, ND, ND, ND, 5.295. Excrement: 0.002, 0.028, 0.143, 0.081, 0.083 (ppm). DDD RAPI adult TISPREP PHYSIO 2 x10 -4 M Decrease in skin resistance and increase in short-circuit current. DDD TRSC adult ORAL RESIDUE 23-27 100 body wt 3, 6, 12, 24 h and 3 wks, respectively: Liver: 0.014, 0.204, 0.244, 0.141, 0.109. Brain: 3.166, 2.041, 2.333, ND, 17.194. Fat: ND, ND, ND, ND, 55.55. Excrement: 0.049, 0.041, 0.049, 0.048, 0.221. DDD TRSC adult TISPREP PHYSIO 53, 106 and212 µM Sig. inhibition of brain cell membranes and soluble and light microsomes, as well as highly sig. inhibition of all other fractions occurred at 212 µM. Reference k Owen and Wells 1976 Webb et al. 1979 k Owen and Wells 1976 Witherspoon and Wells 1975 DDD TRSC adult (F) TISPREP PHYSIO Displaced estrogen at binding sites. Crain et al. 1998a DDE ALMI adult TISPREP DEVOBS >50 IC50>50, inhibitor conc. necessary for 50% inhibition of 17ß-estradiol binding to estrogen receptor. Vonier et al. 1996 DDE ALMI adult (F) TISPREP PHYSIO Displaced estrogen at binding sites. Crain et al. 1998a DDE ALMI egg TISPREP DEVOBS DDE in combination with DDD in eggs interacted with 17ßestradiol and reduced binding. Vonier et al. 1996 DDE CHPI adult ORAL RESIDUE 23-27 100 body wt 3, 6, 12, 24 h and 3 wks, respectively: Liver: 0.064, 0.182, 0.163, 0.171, 0.786. Brain: ND, 0.277, ND, 0.179, 0.30. Fat: 1.084, 1.036, 2.553, 2.406, 6.576. Excrement: ND, ND< 0.001, 0.003, 0.018. Owen and Wells 1976 DDE TRSC adult ORAL RESIDUE 23-27 100 body wt 3, 6, 12, 24 h and 3 wks, respectively: Liver: 0.256, 0.292, 0.361, 0.237, 0.230. Brain: 0.284, 0.423, 0.411, 0.007, 0.725. Fat: 7.682, 14.104, 9.003, 8.343, 7.580. Excrement: 0.001, 0.004, ND, 0.001, 0.038. Owen and Wells 1976 DDE TRSC adult TISPREP PHYSIO 53, 106 and In vitro treatment with 212 µM resulted in inhibition of all Witherspoon and Wells 1975 212 µM cellular fractions of the brain. 106 µM had similar effects, except in myelin and cell membranes, where little effect was noted. DDE TRSC adult (F) TISPREP PHYSIO Displaced estrogen at binding sites. Crain et al. 1998a DDOH ALMI adult TISPREP DEVOBS 11.1 IC50= 11.1, inhibitor conc. necessary for 50% inhibition of 17ß-estradiol binding to estrogen receptor. Vonier et al. 1996 DDT ACCR adult DERMAL MORT 21.1- 0.01- 0.05 Field observations following treatment suggested selective Boyd et al. 1963 23.9 g/mL pressures appeared sufficient to have forced expression of resistant genotypes if present in the population. DDT ACGR adult DERMAL MORT 21.1- 0.01- 0.05 Field observations following treatment suggested selective Boyd et al. 1963 23.9 g/mL pressures appeared sufficient to have forced expression of resistant genotypes if present in the population. DDT AGPI juvenile DERMAL PATH Behavioural abnormalities; recovery after 1 wk. Munro 1949
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RATL: A Database of Reptile and Amp
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RATL: A Database of Reptile and Amp
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ABSTRACT Many amphibian and reptile
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PRÉFACE De nombreuses populations
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TABLE OF CONTENTS Abstract………
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LIST OF TABLES Table 1: Contaminant
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INTRODUCTION Why is there a need fo
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Limitations of RATL The RATL databa
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Contaminant a Species Code b Lifest
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Table 1- Field Residues - 20 Contam
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Table 2 - Field Studies - 2 Contami
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Table 2 - Field Studies - 12 Contam
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Table 3: Acute toxicity values from
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Page 149 and 150: Contaminant a Species Code b Lifest
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Table 5: FETAX data. [FETAX (Frog E
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Table 5 - FETAX Studies - 3 Contami
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Contaminant a Contaminant b Concent
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Table 5 - FETAX Studies - 11 Contam
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Table 6: pH study data. (Studies th
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Table 6 - pH Studies - 3 Species Co
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Species Code b Lifestage Study Endp
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Table 6 - pH Studies - 13 Species C
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Table 7: Reviews of primary literat
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Table 7 - Reviews - 3 Review Title
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Table 8 - Population Status - 2 Pop
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Table Notes Note a : see Appendix 2
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References - 2 Anderson, L.M. and R
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References - 4 Bantle, J.A., D.J. F
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References - 6 Beresford, W.A. , M.
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References - 8 Bishop, C.A, P. Ng,
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References - 10 Bragg, A.N. 1964. M
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References - 12 Burke, E.M. and F.H
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References - 14 Chattopadhyay, D.P.
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References - 16 Cooke, A.S. 1974. T
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References - 18 Dash, M.C. and A.K.
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References - 20 DeWitt, J.B., D.G.
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References - 22 Dutta, S.K. and P.
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References - 24 Elisyeyeva, K.H., H
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References - 26 Fontenot, L., C. Ro
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References - 28 Frisbie, M.P. and R
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References - 30 Godet, F., M. Babut
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References - 32 Gunther, R. and J.
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References - 34 Harfenist, A., T. P
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References - 36 Herkovits, J. and C
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References - 38 Hota, A. K. and M.C
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References - 40 Johnson, C.R. 1972a
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References - 42 Karns, D.R. 1984. T
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References - 44 Kraskowski, H.V., K
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References - 46 Leblanc, G.A. and L
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References - 48 Lotshaw, D.P. 1977.
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References - 50 Massot, M., J. Clob
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References - 52 Mendonca, M., J. Sh
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References - 54 Munro, D.F. 1949. E
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References - 56 Oliveira, E.M., D.V
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References - 58 Paulov, S. 1977b. T
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References - 60 Pierce, M.E. 1958.
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References - 62 Raj, T.P., A. Jeban
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References - 64 Rolfe, G. L., A. Ha
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References - 66 Sassaman, J.F. 1978
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References - 68 Semlitsch, R.D. and
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References - 70 Sparling, D.W., T.P
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References - 72 Surova, G.S. and A.
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References - 74 Tomar, V. and A. K.
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References - 76 Vijverberg, H.P.M.,
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References - 78 White, D.H. and A.J
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References - 80 Wyman, R.L. and J.
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Appendix 1a: Species codes in alpha
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Appendix 1a - Species Codes - 3 Cla
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Appendix 1a - Species Codes - 11 Cl
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Appendix 1a - Species Codes - 13 Cl
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Appendix 1b - Species Common Names
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Appendix 1c - Species Scientific Na
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Appendix 2a: Contaminant codes foun
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Appendix 2a - Contaminant Codes - 3
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Appendix 2b: Contaminants sorted by
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Appendix 2b - Contaminant Type - 3
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Appendix 4: Descriptions of exposur
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Appendix 6a: Glossary of Abbreviati
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Appendix 6b: Relevant biological an
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Appendix 6b - Glossary of RATL term
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RATL: A Database of Reptile and Amphibian Toxicology Literature

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