RATL: A Database of Reptile and Amphibian Toxicology Literature

Contaminant a Species
Code b
Lifestage Exposure
Route f
Table 4 - Laboratory Studies - 54
Study
Endpoint g Temp h pH Contaminant
Concentration
e
Results, Residues, Effects and/or Remarks d,e
Reference k
PCB EUNO adult ENVIRON PHYSIO Histopathological lesions in liver and kidney consistent with
poisoning. PCB levels in liver and fat were relatively high.
Wojcik et al. 1995
PCB PYMB adult ENVIRON PHYSIO Histopathological lesions found in liver and kidney. PCB
levels in liver and fat were relatively high.
Wojcik et al. 1995
PCB PYRG adult ENVIRON PHYSIO Histopathological lesions found in liver and kidney. PCB in
liver and fat relatively high.
Wojcik et al. 1995
PCB RACA adult ORAL PATH Dose-dependent decrease in helminth intensity and nematode
abundance was observed in RACA. A highly sig. dosedependent
increase in enzyme activity occurred.
Fontenot et al. 1995b
PCB RACA adult ORAL PATH 10-300 Neither the number of nematode species nor the number of
trematode species were affected by the treatment of surviving
or dead frogs. There was a dose dependent decrease in parasite
burden in those frogs that survived the exposure period.
Fontenot et al. 1995a
PCB RAES adult INJECT PHYSIO 250 Frogs had limited metabolism of PCB-replacement
compounds.
Tulp et al. 1977
PCB TRSC egg DERMAL DEVOBS 27.8 10-190 µg 11 different PCBs tested. Increased number of females and
increased number of hatchlings with oviducts.
Bergeron et al. 1994
PCB 126 RAPI adult INJECT PHYSIO 7.8 Transparent or yellow kidneys, EROD and MROD enzyme
activity increased slightly in 7.8mg/kg.
Huang et al. 1998
pentachlorobenzene RAPI adult INJECT PHYSIO Metabolites of substances were isolated and identified by
chromatographic and spectroscopic methods.
Safe et al. 1976
pentachlorophenol CACU embryo IMMER GENOTOX 18 15 ppb-1.5 Frequency of micronucleated erythrocytes are given for each
conc. 1.5 ppm, 100% embryos died; 300 ppb, 46% embryos
died; 150 ppb, 5% embryos died after 92 h.
Venegas et al. 1993
pentachlorophenol EUOS adult INHAL MORT 1-2% 3 h lethal time for both conc. Kihara and Yamashita 1978
pentachlorophenol PLTH adult TISPREP PHYSIO 20-22 7.2 0.003- 0.1 mM Dose-time dependent block of evoked transmitter release in
sartorius muscle.
Montoya and Quevedo 1990
pentachlorophenol XELA < 2 d IMMER MORT 20 100 d NOEL: Mortality= 0.032; Development= 0.032;
Growth= 0.032 mg/L.
Slooff and Canton 1983 k
permethrin AGAG adult IMMER PATH 0.05- 0.1 mg Conc. that controls ectoparasites in snakes, not toxic. Mutschmann et al. 1991
permethrin AGCA adult IMMER PATH 0.05- 0.1 mg Conc. that controls ectoparasites in snakes, not toxic. Mutschmann et al. 1991
permethrin BOCO adult IMMER PATH 0.05- 0.1 mg Conc. that controls ectoparasites in snakes, not toxic. Mutschmann et al. 1991
permethrin BUAM embryo IMMER HATSUC 0.01- 0.1 mg/L 95-99% hatching success; no increase in gross abnormality
rate.
Berrill et al. 1993
permethrin RACL embryo IMMER HATSUC 15 0.01- 0.1 mg/L No increase in gross abnormality rate; dose and stage
dependent variation in twisting response; 95-99% hatching
success.
Berrill et al. 1993
permethrin RACL embryo IMMER DEVOBS 15 0.1-2.0 mg/L Treated embryos grew sig. slower; malformations observed;
behaviour abnormalities.
Berrill et al. 1993