RATL: A Database of Reptile and Amphibian Toxicology Literature

Contaminant a Species
Code b
Lifestage Exposure
Route f
Table 4 - Laboratory Studies - 21
Study
Endpoint g Temp h pH Contaminant
Concentration
e
Results, Residues, Effects and/or Remarks d,e
Reference k
DDT RAPI adult TISPREP PHYSIO 2 x10 -4 M Exposure did not produce a short circuit current or resistance
in abdominal skin.
Webb et al. 1979 k
DDT RAPI adult DERMAL RESIDUE 1 Half time of dermal penetration 703 mins.
Shah et al. 1983 k
DDT RAPI adult INJECT BEHAV 100 Increased activity, violent leg extensions after 6 h
maintained till death.
Isaacon 1968 k
DDT RAPI adult IMMER MORT Mortality occurred in: 2 of 3 fed poisoned insects, 1 of 1
sprayed with 1 drop DDT on water, 1 of 2 sprayed with
standard spray.
Logier 1949
DDT RAPI tadpole
(limb bud)
IMMER DEVOBS 5, 25 ppb Tail regeneration (mm) reduced at higher DDT conc. All
exposed individuals exhibited reduced regeneration.
Weis 1975 k
DDT RARI adult TISPREP PHYSIO 5 x10 -4
Prevented Ca binding in globular phospholipidic micelles and
facilitated Ca removal from the laminar phospholipidic
micelles.
Craciun et al. 1981 k
DDT RASE adult IMMER MORT 100% mortality occurred within 9 d. Logier 1949
DDT RASY adult IMMER MORT One specimen was fed 5 poisoned insects but was unaffected. Logier 1949
DDT RASY adult IMMER RESIDUE 0.001- 0.003
ppm
Only trace residues found in head, lung, gut and rest of body.
High conc. in liver and fat.
Licht 1976a k
DDT RASY embryo IMMER HATSUC 0.025 ppm No abnormal effects on morphology or hatching success of
embryos in stages 13, 16, or 18 to 0.025 ppm for 24 h; signs
of DDT poisoning observed in embryos treated at stage 20.
Licht 1985 k
DDT RASY embryo IMMER RESIDUE 9-21 0.025 ppm Stage 13= 0.188 at 9°C - 0.167 at 21°C; stage 16= 0.142 -
1.58; stage 18=.145 - 0.160; stage 20= 0.956 - 1.57 Jelly
content= 0.015 - 0.019.
Licht 1985 k
DDT RASY tadpoles IMMER RESIDUE 15-21 0.001- 0.003
ppm
Liver tissue levels reached max at 24 h.
Licht 1976b k
DDT RATE adult INJECT BEHAV Behavioural abnormalities.
Cooke 1974 k
DDT RATE adult IMMER RESIDUE Exposure for 1 h. Residues: DDT= 1.3 - 16 % of that
originally present in test medium.
Cooke 1970 k
DDT RATE adult INJECT RESIDUE 12 Liver 16.9 ppm; muscle 1.4 ppm.
Cooke 1974 k
DDT RATE adult ORAL RESIDUE Residues: tissue DDT conc. was correlated with fat conc. of
tissues; strong accumulation in fat body, liver, gall bladder,
ovary, spleen and bones; minimal accumulation in spinal
cord; no activity in kidney, oviduct, heart or skeletal muscle.
Harri et al. 1979 k
DDT RATE adult ORAL PHYSIO 5 ppm Single dose of DDT did not affect the activities of hepatic
mixed function oxidase components.
Harri 1980
DDT RATE egg
(spawn)
IMMER BEHAV 0.5 Hyperactive 8 - 13 d after hatching. Development and weight
Cooke 1972b
gain were retarded. Exposure to 0.5 ppm when ova beginning
to elongate or when head and body of each tadpole
distinguishable had no effect.
k