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RATL: A Database of Reptile and Amphibian Toxicology Literature

RATL: A Database of Reptile and Amphibian Toxicology Literature

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Contaminant a Species<br />

Code b<br />

Lifestage Exposure<br />

Route f<br />

Table 4 - Laboratory Studies - 64<br />

Study<br />

Endpoint g Temp h pH Contaminant<br />

Concentration<br />

e<br />

Results, Residues, Effects <strong>and</strong>/or Remarks d,e<br />

Reference k<br />

temephos BUBO juvenile IMMER PHYSIO 23-24 Exposure <strong>of</strong> hydrated toads to 60 ppb sig. lowered temp<br />

tolerance.<br />

Johnson <strong>and</strong> Prine 1976 k<br />

temephos HYRE tadpole (3<br />

wk)<br />

IMMER PHYSIO 25-50 ppb Temp tolerance sig. lowered.<br />

Johnson 1980a k<br />

temephos RACH not<br />

specified<br />

IMMER 1-100 Japanese paper. Hattori 1974<br />

temephos RACL tadpoles IMMER BEHAV 0-10 µl/L By 24 h <strong>of</strong> exposure, half <strong>of</strong> the tadpoles at the highest conc. Sparling et al. 1997<br />

died. At the end <strong>of</strong> 96 h, % mortality ranged from 0% at 1.86<br />

µl/L <strong>and</strong> 100% at 10 µl/L.<br />

TEPP RAPI adult IMMER PHYSIO 10-80 Increasing conc. resulted in anemia, leucopenia; differential<br />

white cell count showed neutropenia <strong>and</strong> lymphocytosis, red<br />

blood cells distorted in shape, visceral organs desiccated,<br />

spasticity in hindlimbs.<br />

Kaplan <strong>and</strong> Glaczenski 1965 k<br />

TETD MIOR embryo IMMER DEVOBS 0-2.5 mg/L 50% mortality at 1 mg/L, 100% mortality at 2 mg/L. Other<br />

effects were bent notochord, pigmentation, edema, other<br />

tissue disarrays. Abnormality incidence 100% at 0.5 mg/L.<br />

Ghate 1983<br />

TETM MIOR embryo IMMER DEVOBS 0-5 mg/L Mortality: 100% at 5 mg/L, 20% at 3 mg/L. Bent notochord,<br />

pigmentation, edema, other tissue disarrays, abnormality<br />

incidence was 100% at 2 mg/L.<br />

Ghate 1983<br />

tetrachlorobenzene RAPI adult INJECT PHYSIO Metabolites <strong>of</strong> substances were isolated <strong>and</strong> identified by<br />

chromatographic <strong>and</strong> spectroscopic methods.<br />

Safe et al. 1976<br />

tetrahydr<strong>of</strong>uran DEXX adult DERMAL BEHAV 2, 16 <strong>and</strong> 25 Hyperactivity; weight loss; no mortality immediately after<br />

exposure.<br />

Whitaker 1993<br />

TFM RACA egg IMMER DEVOBS 0.1-3.0 mg/L Arrested growth at conc. greater than 1.0 mg/L, following<br />

development in the next 96 h.<br />

Kane et al. 1993<br />

TFM RACA larvae IMMER MORT 7.5 mg/L No tadpoles recovered after treatment. Kane <strong>and</strong> Johnson 1989<br />

TFM RACA tadpoles IMMER DEVOBS 2.0 mg/L No adverse effects observed. Kane et al. 1993<br />

TFM RACL larvae IMMER MORT 7.5 mg/L Treatment effective in controlling larvae in treated ponds. Kane <strong>and</strong> Johnson 1989<br />

thalium XXFR embryo IMMER MORT N/500000 (see<br />

paper for<br />

details)<br />

Tadpoles killed on emergence.<br />

Dilling <strong>and</strong> Healey 1926 k<br />

thallium sulfate PICA adult ORAL MORT 11 rats, fed<br />

avg. <strong>of</strong> 5.27<br />

Mg<br />

No effects were observed on snakes. Brock 1965<br />

thiabendazole ELOO adult ORAL PATH 110 Thiabenzadole is a treatment for parasites; species<br />

completely recovered after treatments.<br />

Holt et al. 1979<br />

thiabendazole ELOQ adult ORAL PATH 110 Thiabenzadole is a treatment for parasites; this species died<br />

after 4th treatment, 24 h with different symptoms than<br />

PYRE. Death caused by nematode parasitism.<br />

Holt et al. 1979

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