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RATL: A Database of Reptile and Amphibian Toxicology Literature

RATL: A Database of Reptile and Amphibian Toxicology Literature

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Contaminant a Species<br />

Code b<br />

Lifestage Exposure<br />

Route f<br />

Table 4 - Laboratory Studies - 26<br />

Study<br />

Endpoint g Temp h pH Contaminant<br />

Concentration<br />

e<br />

Results, Residues, Effects <strong>and</strong>/or Remarks d,e<br />

dieldrin BUAR embryo IMMER PHYSIO 0.02-2 mg/L Embryos developed in 0.2 <strong>and</strong> 20 mg/L died between 20 -2 5<br />

d: 25-30% <strong>of</strong> those developed in 0.02 mg/L had front legs<br />

earlier than controls.<br />

dieldrin BUAR embryotadpole<br />

IMMER RESIDUE 0.02-2.0 mg/L Behavioural abnormalities; decreased phospholipid content<br />

<strong>and</strong> altered morphology; no effect on body weight, protein<br />

content <strong>and</strong> enzyme activities.<br />

Reference k<br />

de Llamas et al. 1985 k<br />

Gauna et al. 1991<br />

dieldrin BUAR larvae IMMER PHYSIO 0.02-2.0 mg/L Hyperactivity in larvae, change in AChE activity.<br />

de Llamas et al. 1985 k<br />

dieldrin BUAR oocytes IMMER PHYSIO 4 mg/L Authors suggest that after agonist-dependent hydrolysis <strong>of</strong> Fonovich De Schroeder et al.<br />

phosphonositides, PIP <strong>and</strong> PIP2 kinases are activated in<br />

control but not in dieldrin-treated oocytes.<br />

1991<br />

dieldrin BUAR oocytes TISPREP PHYSIO 0-50 6-10 10 -5 - 10 -12 M Phospholipase C activity interacted with dieldrin. Enhanced<br />

degradative activity was noticed for doses from 10 -9 to 10 -7<br />

deSchroeder <strong>and</strong> d'Angelo<br />

M.<br />

1995<br />

dieldrin BUBU tadpoles IMMER RESIDUE 0.02- 0.5 3.4 - 138 ppm (24-48 h).<br />

Cooke 1972b k<br />

dieldrin BUBU tadpoles IMMER BEHAV 0.5 No mortality; behaviour <strong>and</strong> snout abnormalities.<br />

Cooke 1972b k<br />

dieldrin EUOS adult INHAL MORT 1-2% 24 h lethal time to survival past 3 d at 1% conc. Kihara <strong>and</strong> Yamashita 1978<br />

dieldrin GRGE adult (F) TISPREP PHYSIO 0.53, 5.3 <strong>and</strong> Inhibition <strong>of</strong> Na, K <strong>and</strong> Mg dependent ATPase may have Wells et al. 1974<br />

53 µM been related to cell membrane alteration.<br />

dieldrin LITA embryo IMMER DEVOBS 0.01- 0.1 Otolith, otic capsule <strong>and</strong> cephalic pigmentation abnormalities<br />

Brooks 1981<br />

after exposure to 0.1 ppm for 7 h; acceleration <strong>of</strong> growth<br />

relative to controls. No effects at 0.01 ppm.<br />

k<br />

dieldrin RACA embryo IMMER MORT

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