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RATL: A Database of Reptile and Amphibian Toxicology Literature

RATL: A Database of Reptile and Amphibian Toxicology Literature

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Contaminant a Contaminant<br />

b<br />

Concentration<br />

b<br />

LC50<br />

xylenes 100-200 mg/L 54-135<br />

(test<br />

range)<br />

Zn 25.35 -<br />

28.65<br />

Zn 1-3000 µmol/L 850<br />

µmol/L<br />

ZnSO4 34.4 mg/L<br />

(inactive)<br />

ZnSO4 7 day<br />

LC50 =<br />

34.5<br />

EC50 b<br />

ND-299<br />

(test<br />

range)<br />

TI d<br />

ND-1.34<br />

(test<br />

range)<br />

Table 5 - FETAX Studies - 22<br />

MCIG d<br />

2.65 - 9.57 -<br />

2.83 10.12<br />

40 µmol/L 21 300<br />

µmol/L<br />

2.7 mg/L<br />

(inactive)<br />

36<br />

13.3<br />

(inactive)<br />

NOEL d<br />

LOEL d<br />

Effects/Notes de<br />

mortality<br />

(61-141);<br />

malform<br />

(41-118);<br />

growth<br />

(47->118)<br />

1.75 - 2.0 Results also given for metal contaminated<br />

soils.<br />

Reference k<br />

Kononen <strong>and</strong> Gorski 1997<br />

Fort et al. 1995b<br />

Shown to be a potent teratogen for Luo et al. 1993a<br />

XELA causing conc. related increases <strong>of</strong><br />

eye, gut, facial, notochord, fin, <strong>and</strong><br />

cardiac anomalies. Head to tail lengths<br />

were inversely correlated with Zn conc.<br />

Activated tests resulted in an LC50 <strong>of</strong> Fort et al. 1989<br />

36.7 mg/L <strong>and</strong> an EC50 <strong>of</strong> 2.9 mg/L. The<br />

TI for activated tests was 12.7. Embryos<br />

exposed to ZnSO4 alone at conc. <strong>of</strong> >1.5<br />

mg/L caused mild gut malformations &<br />

pericardial edema.<br />

Dawson et al. 1988b k

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