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o-TOLUIDINE CAS N°: 95-53-4 - UNEP Chemicals

o-TOLUIDINE CAS N°: 95-53-4 - UNEP Chemicals

o-TOLUIDINE CAS N°: 95-53-4 - UNEP Chemicals

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OECD SIDS o-<strong>TOLUIDINE</strong><br />

3. ENVIRONMENTAL FATE AND PATHWAYS ID: <strong>95</strong>-<strong>53</strong>-4<br />

DATE: 07.01.2005<br />

Deg. product :<br />

Method : other: Calculation method<br />

Year : 1996<br />

GLP :<br />

Test substance : other TS: o-toluidine<br />

Method : Biodegradadtion rates in soil, expressed as half-lives, are correlated with<br />

molecular groups using a neural network. A back-propagation neural<br />

network with 14 input nodes, 12 nodes in the hidden layer and 2 output<br />

nodes, is used to correlate the input data with the log values of the high<br />

and low soil half-lives for each chemical in database. The range of halflives<br />

for organic contaminants in soil was estimated.<br />

Result : A high soil half-live for o-toluidine was estimated to be 18.1 d. 3.5 d was<br />

estimated for the low soil half-live.<br />

Reliability : (4) not assignable<br />

Not commonly used calculation method<br />

18.06.2004 (88)<br />

Type : aerobic<br />

Inoculum : other: Mixture of sludge from different sources, non-adapted<br />

Contact time :<br />

Degradation : 5 (±) % after 28 day(s)<br />

Result :<br />

Deg. product :<br />

Method : OECD Guide-line 301 C "Ready Biodegradability: Modified MITI Test (I)"<br />

Year : 2000<br />

GLP : no data<br />

Test substance : other TS: o-Toludine, purity not specified<br />

Result : 5 % degradation related to BOD<br />

1 % degradation related to TOC<br />

0 % degradation determined with HPLC<br />

Test condition : - Initial concentration of inocolum: 30 mg/l<br />

- Initial concentration of test substance: 100 mg/l<br />

- Different analysis methods used: BOD, TOC and HPLC<br />

Reliability : (2) valid with restrictions<br />

Basic data given<br />

11.11.2004 (32)<br />

3.6 BOD5, COD OR BOD5/COD RATIO<br />

3.7 BIOACCUMULATION<br />

Species : other: Crassostrea gigas (Pacific oyster)<br />

Exposure period : 24 hour(s) at 15 °C<br />

Concentration : 5 mg/l<br />

Elimination :<br />

Method : other<br />

Year : 1985<br />

GLP : no data<br />

Test substance : other TS: o-Toluidine, ring-labeled [14C], specific activity: 18.2 mCi/mM<br />

(radiopurity > 99 %, tested by HPLC)<br />

Method : - Oysters were obtained from a clean body of water (Johnson Oyster Co.,<br />

Drakes Bay, California).<br />

- Single mussels were exposed in 3 replicates.<br />

- o-Toluidine loss was observed.<br />

- BCF was determined at equilibrium.<br />

<strong>UNEP</strong> PUBLICATIONS 101

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