o-TOLUIDINE CAS N°: 95-53-4 - UNEP Chemicals

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OECD SIDS o-TOLUIDINE 3. ENVIRONMENTAL FATE AND PATHWAYS ID: 95-53-4 DATE: 07.01.2005 80 Type of measurement : concentration at contaminated site Media : ground water Concentration : Method : GC/MS Method : - Samples taken 15 months after underground coal gasification was terminated - Ground water samples extracted with CH2Cl2 and fractionated into acidic, basic, and neutral fractions - Direct injection of fractions concentrate into GC - GC (Hewlett-Packard 5880, SP2100-fused silica column, flame ionization detector) - Identification of peaks by GC/MS (Hewlett-Packard 5985) Result : 3 ground water samples from the vicinity of an US underground coal gasification site, contained toluidine in concentrations of up to 9.2 µg/l (sum of o- and p-isomers: 0.06, 1.4, 9.2 µg/l) Reliability : (2) valid with restrictions Basic data given Flag : Critical study for SIDS endpoint 07.06.2004 (49) Type of measurement : other: background, contaminated sites Media : other: effluents from refineries and production facilities, river water, process water, and ground water Concentration : Method : Result : o-Toluidine was detected in the effluents from refineries and production facilities, in river water, process water, and ground water (cited according to NTP 2003, no further data supplied) Reliability : (4) not assignable Secondary literature Flag : Critical study for SIDS endpoint 07.06.2004 (50) Type of measurement : other: background, contaminated site Media : other: surface water and open sewer Concentration : Method : Method : In 1991, o-toluidine was monitored in several rivers in North Rhine- Westfalia in Germany Remark : The Emscher serves as an open sewer for an urban and industrial area with several millions of inhabitants Result : o-Toluidine was only detected in the Emscher (highest value: 1.8 µg/l, detection limit in most rivers 1 µg/l, detection limit in the Wupper 0.1 µg/l) Reliability : (2) valid with restrictions Basic data given Flag : Critical study for SIDS endpoint 03.06.2004 (51) Type of measurement : concentration at contaminated site Media : surface water Concentration : Method : Solid Phase Extraction, followed by HPLC with Diode Array Detection Result : From March 1994 to August 1995, o-toluidine was occasionally found in the rivers Bilina (downstream of a chemical factory in Usti nad Labem = Aussig, Czech Republic) and in the Elbe (no exact values reported). The relative concentrations of the sum of several aromatic amines examined UNEP PUBLICATIONS
OECD SIDS o-TOLUIDINE 3. ENVIRONMENTAL FATE AND PATHWAYS ID: 95-53-4 DATE: 07.01.2005 were (Elbe in Dresden, Germany = 1): - Bilina, tributary of the Elbe in the Czech Republic: 4-6 - Elbe in the Czech Republic: 2-3 - Elbe in Dresden, Germany: 1 The authors assumed that the irregular occurence and concentration pattern of these amines indicated a significant input of untreated wastewater from batch production in chemical factories in the Czech Republic. Several samples taken from river sites in Saxony demonstrated that no significant input of aromatic amines occured in Germany. Reliability : (2) valid with restrictions Basic data given Flag : Critical study for SIDS endpoint 08.06.2004 (52) Type of measurement : concentration at contaminated site Media : surface water Concentration : Method : Solid Phase Extraction, followed by HPLC Remark : Boernick et al. (2001) refer to Boernick (1998) Result : In 1994-1996, o-toluidine was monitored in the Elbe and some of its tributaries in Germany and the Czech Republic (Boernick, 1998). With a detection limit of 28 ng/l, o-toluidine was detected in the following waters: · Bilina river, vicinity of the confluent with the river Elbe in Usti (Aussig, Czech Republic), but downstream of the wastewater outlet of an azo dye producer, in 1 out of 7 samples: >21,200 ng/l (value out of the calibration range). o-Toluidine was not detected upstream of this outlet · Elbe in Czech Republic, 2 sampling sites downstream confluent with Bilina, in 2 out of 6 samples: 30 and 1,130 ng/l, respectively. o-Toluidine was not detected upstream of the confluent of Elbe and Bilina · Elbe, Pillnitz (Saxony, Germany), km 43 from Czech border, in 1 out of 13 samples: 122 ng/l · Elbe, Dresden (Saxony, Germany), km 55 from Czech border, in 3 out of 56 samples: 93, 110, and 1,010 ng/l · Other sites in Saxony (Germany), in 3 out of 45 samples: 70, 72, and 191 ng/l. Reliability : (2) valid with restrictions Basic data given Flag : Critical study for SIDS endpoint 08.06.2004 (53) (54) Type of measurement : concentration at contaminated site Media : surface water Concentration : Method : Solid Phase Extraction, followed by GC/MS Remark : The limit of detection obtained with external calibration is given as 8.6 ng/l and the limit of determination as 25.4 ng/l (Eppinger 2000). Result : Between March 1997 and March 1998, 52 random samples were taken from the river Elbe at Pillnitz (Saxony, Germany; 43 km from Czech border). o-Toluidine occured in 6 % (3) of the samples with a maximum of 0.04 µg/l and an average of 0.03 µg/l for these 3 samples. Other result (Eppinger 2000) were: · Elbe at Kötitz (Saxony, Germany; 73 km from Czech border). o-Toluidine occurred in 2 of 12 samples (0.064 µg/l and 0.039 µg/l) · Elbe at Scharfenberg (Saxony, Germany; 76.5 km left side from Czech border). o-Toluidine occurred in 2 of 13 samples (0.059 µg/l and 0.03 µg/l) · Elbe at Meißen (Saxony, Germany; 76.5 km right side from Czech border). o-Toluidine was not detected in 12 samples (LOD: 0.025 µg/l) · Elbe at Torgau (Saxony, Germany; 153 km from Czech border). o- Toluidine occurred in 1 of 3 samples (0.03 µg/l) UNEP PUBLICATIONS 81
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OECD SIDS o-TOLUIDINE FOREWORD INTR
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OECD SIDS o-TOLUIDINE 11. Comments:
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o-TOLUIDINE CAS N°: 95-53-4 - UNEP Chemicals

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